Such defective sheaths often arise from genetic mutations affecting the biosynthesis and formation of myelin.

Such mutations may cause drug resistance.

Such de novo mutations are the result of a germ cell mutation or germ cell mosaicism in the gonads of one of the parents, or a mutation in the fertilized egg itself.

Such mutations can cause two genetic disorders, congenital bilateral absence of vas deferens and the more widely known disorder cystic fibrosis.

Such mutations are responsible for diseases such as Epidermolysis bullosa, sickle-cell disease, and SOD1 mediated ALS.

Such scenarios however remain speculative until such time as more compelling evidence for the avian affinity of any of the Protoavis material is brought forth.

Such contact can also lead to more mundane infections from common bacteria and viruses found in, around and secreted from the genital regions.

Such enzymes, found in bacteria and archaea, are thought to have evolved to provide a defense mechanism against invading viruses.

Such hypermutation can be lethal to RNA viruses.

Such is the case with the viruses V2000 and V2100, which claim to be written by Vesselin Bontchev, in an attempt to cause defamation.

Such programs are known as malware and come in many forms, such as viruses, Trojan horses, spyware, and worms.

Such programs are used to detect and usually eliminate viruses ; however, it is now common to see security suites, containing also firewalls, anti-spyware, theft protection, and so on to more thoroughly protect users.

Such diseases were originally thought to be caused by viruses, which, like phytoplasmas, require insect vectors, cannot be cultured, and have some symptom similarity.

Such drugs are effective only against viruses from the herpes group with their specific thymidine kinase.

Such software includes computer viruses ( rarely ), spyware, and DRM software such as MediaMax.

Such genuine human leadership the proprietorship can offer, corporations cannot.

Such high-resolution observations as these are needed at several wave lengths in order that the radio emission of the moon can be properly interpreted.

Such pseudo-questions assume that answers of concrete significance can be supplied to statements involving undefined universals.

`` Such a vicious statement can only have its origin in the desire of a new political candidate to try to make his name known by condemning a man of world stature.

Such a calm and assuring peace can be yours.

Such an ordering is not necessarily a numbering, but can be used to construct a numbering by fiat.

Such phrases can be assigned different interpretations because different grammatical structures can be assigned to the same string of words.

But humans can do something equally useful, in the case of certain enumerably infinite sets: They can give explicit instructions for determining the nth member of the set, for arbitrary finite n. Such instructions are to be given quite explicitly, in a form in which they could be followed by a computing machine, or by a human who is capable of carrying out only very elementary operations on symbols.

Such modifications can also determine the localization of the protein, e. g., the addition of long hydrophobic groups can cause a protein to bind to a phospholipid membrane.

Such temperature changes can be quantified using the ideal gas law, or the hydrostatic equation for atmospheric processes.

Such a description language can be based on any computer programming language, such as Lisp, Pascal, or Java Virtual Machine bytecode.

Such claims can be found among the worldwide community of Christians.

Such a coating can protect an iron structure for a few decades, but once the protecting coating is consumed, the iron rapidly corrodes.

Such a trinity of freedom of thought is the only guarantee against an infection of people by mass myths, which, in the hands of treacherous hypocrites and demagogues, can be transformed into bloody dictatorship.

Such withdrawal effects can include cholinergic rebound, an activation syndrome, and motor syndromes including dyskinesias.

Such drinks are legally classified as beers in virtually all states and can therefore be sold in outlets that do not or cannot carry spirit-based drinks.

Such collectors can use relatively exotic technologies, such as vacuum insulation, and reflective concentration of sunlight.

Such devices can link computers with Bluetooth with a distance of 100 meters, but they do not offer as many services as modern adapters do.

Such influences can be overstated: Gropius himself did not share these radical views, and said that Bauhaus was entirely apolitical.

Such influence has caused Aramaic to have many Persian loanwords that can be seen in later historical texts.

Such extensions typically remain NP-complete, but very efficient solvers are now available that can handle many such kinds of constraints.

Such computers are more versatile in that they do not need to have their hardware reconfigured for each new program, but can simply be reprogrammed with new in-memory instructions ; they also tend to be simpler to design, in that a relatively simple processor may keep state between successive computations to build up complex procedural results.

Such a revision, he said, would ruin it, would change his whole conception of the play as well as the treatment.

Such modifications are all for the best but it takes something as different as a Deerstalker or a Jet to change arms-making concepts.

Such a move adds greatly to the risk of having to face the doubling cube coming back at 8 times its original value when first doubling the opponent ( offered at 2 points, counter offered at 16 points ) should the luck of the dice change.

Such a body is said to change reversibly.

Such individuals were strongly committed to political change that would ensure constitutional support in Taiwan for freedoms of speech, press, assembly, and association.

Such factors include capital accumulation, technological change and labor force growth.

Such an event is identified by a sharp change in the diversity and abundance of macroscopic life.

Such disappearances are considered to be results of climate change or the proliferation of modern humans, or both.

Such electrons can therefore easily change from one energy state into a slightly different one.

Such interactions and their associated conformational change has been measured using dual polarisation interferometry.

Such mechanisms of rapid speciation can reflect a mechanism of evolutionary change known as punctuated equilibrium, which suggests that evolutionary change and in particular speciation typically happens quickly after interrupting long periods of stasis.

Such change will enable delayed making of manufacturing or procurement decisions, thus reducing variability found in having many non-standard components.

In 1987 Bill Elliot's asphalt blistering qualifying time at Talladega brought about a change at superspeedways ( Daytona and Talladega ). Such high speeds and Bobby Allison's car going airborne into the catch-fence and injuring fans forced NASCAR to implement power-reducing measures, one of which was the mandated implement of below carburetor restrictor plates.

Such behavioral traditions may have evolutionary significance, allowing adaptation at a faster rate than genetic change.

Such a change is sufficient if unforeseen, if it undermined the “ essential basis ” of consent by a party, if it radically transforms the extent of obligations between the parties, and if the obligations are still to be performed.

According to special relativity, one can change a spatial and time separation ( L < sub > 1 </ sub >, Δt < sub > 1 </ sub >) into another ( L < sub > 2 </ sub >, Δt < sub > 2 </ sub >) by changing one's reference frame, as long as the change maintains the spacetime interval s. Such a change in reference frame corresponds to changing one's motion ; in a moving frame, lengths and times are different from their counterparts in a stationary reference frame.

Such unprecedented levels of computational power are key to investigating areas, such as designing fusion reactors that could provide carbon neutral, sustainable energy ; engineering proteins to provide new therapies for diseases or release energy from biomass efficiently ; studying climate change ; and designing new materials with specialized properties.

Such people are unhappy, and their desire to change the system can destabilize the society.

Such a file would allow the attacker to " then install programs ; view, change, or delete data ; or create new accounts with full user rights ", if the account on which the file was played had administrator privileges.

Such quantities are the same in every coordinate system, so these infinities will not " go away " by a change of coordinates.

Such a name change would become final if within their jurisdiction, once a federal court naturalizes an applicant.

Such documents are mere evidence that a change of name has occurred, however, and they do not themselves operate to change a person's name.