The novel chronicles the continued struggles of the Bene Gesserit Sisterhood against the violent Honored Matres, who are succeeding in their bid to seize control of the universe and destroy the factions and planets that oppose them.

Now they must survive the Honored Matres, whose reckless conquest of the Old Empire threatens Bene Gesserit survival.

The situation is desperate for the Bene Gesserit as they find themselves the targets of the Honored Matres, whose conquest of the Old Empire is almost complete.

Now in command of the Bene Gesserit, Mother Superior Darwi Odrade continues to develop her drastic, secret plan to overcome the Honored Matres.

The Bene Gesserit have two other prisoners on Chapterhouse: the latest Duncan Idaho ghola, and former Honored Matre Murbella, whom they have accepted as a novice despite their suspicion that she intends to escape back to the Honored Matres.

Lampadas, a center for Bene Gesserit education, has been destroyed by the Honored Matres.

Lucilla is then " betrayed ", and taken before the Great Honored Matre Dama, who tries to persuade her to join the Honored Matres, preserving her life in exchange for Bene Gesserit secrets.

Odrade appoints him again as Bashar of the military forces of the Sisterhood for the assault on the Honored Matres.

Odrade next calls a meeting of all the Bene Gesserit, announcing her plan to attack the Honored Matres.

Logno — chief advisor to Dama — assassinates Dama with poison and assumes control of the Honored Matres.

Too late Odrade and Teg realize they have fallen into a trap, and the Honored Matres use a mysterious weapon to turn defeat into victory, as well as capturing Odrade.

Awed by her physical prowess, the remaining Honored Matres are forced to accept her as their new leader.

The story ends on a cliffhanger with several questions left unanswered regarding the merging of the Honored Matres and Bene Gesserit, the fates of those on the escaped no-ship ( including the role of Scytale, the development of Idaho and Teg, and the role of the Jews ), the identity of the god-like characters in the book's final chapter and the ultimate mystery of what chased the Honored Matres back into the Old Empire.

The most powerful of these forces are the Honored Matres, a violent society of women bred and trained for combat and the sexual control of men.

Above the planet Gammu, Taraza is captured and held hostage by the Honored Matres aboard an Ixian no-ship.

The Honored Matres insist Taraza invite Teg to the ship, hoping to gain control of the ghola project.

Taraza arranges a meeting with the Tleilaxu Master Waff, who is soon forced to tell her what he knows about the Honored Matres.

Lucilla arrives at a Bene Gesserit safe house to discover it has been taken over by Honored Matres, who have Idaho as their captive.

The Honored Matres attack Rakis, killing Taraza.

By the events of Chapterhouse: Dune ( 1985 ), the Bene Tleilax have been all but eradicated by the fierce Honored Matres save for one Master, Scytale ; he is a ghola of the original Scytale of Dune Messiah, somehow having ascended from Face Dancer to Master.

Further, in Heretics of Dune, Odrade theorizes that the Honored Matres may have been driven back from the Scattering as their subjects have developed resistance to their form of Voice control due to its over use.

In Chapterhouse Dune ( 1985 ), the Honored Matres have destroyed all of the Tleilaxu worlds in retaliation for the Tleilaxu role in programming the latest Duncan Idaho ghola with knowledge of how to sexually enslave Honored Matres.

The Bene Gesserit have accepted Murbella as a novice and are training her to be a Sister, despite their belief that she intends to steal their secrets and escape back to the Honored Matres.

Though the Honored Matres had destroyed all Bene Tleilax worlds, their descendants ( the Lost Tleilaxu ) have returned from The Scattering.

According to various excerpts, Futars can find and destroy Honored Matres, and are rumored to have been created and used by the " Ones of Many Faces " in their devastating attack against the Honored Matres in The Scattering.

Teg also goes to a supposed safe house, only to discover the Honored Matres.

The full official name is Makkat al-Mukarramah (, or ), which means " Mecca the Honored ", but is also loosely translated as " The Holy City of Mecca ".

* He also Honored with “ Proud Past Alumni " in the list of 42 members, from " Allahabad University Alumni Association ", NCR, Ghaziabad ( Greater Noida ) Chapter 2007-2008 registered under society act 1860 with registration no.

* She also Honored with “ Proud Past Alumni " in the list of 42 members, from " Allahabad University Alumni Association ", NCR, Ghaziabad ( Greater Noida ) Chapter 2007-2008 registered under society act 1860 with registration no.

As the original Teg has been trained by his mother to resist such manipulation, the attempt subjects the Teg ghola to a heightened amount of stress which also unlocks the superhuman abilities acquired by Teg under Honored Matre torture in Heretics of Dune.

Honored twice by the Montana Library Association for his fight against governmental agencies ' spying on law-abiding citizens ( 2001 Legislator Award, 2006 Pat Williams Intellectual Freedom Award ), Jim is also a Fellow of the Eleanor Roosevelt Global Leadership Institute and the Arthur Fleming Leadership Institute.

Murbella also discovers how the Honored Matres first provoked the " Enemy ".

Murbella also ' remembers ' the attack by a renegade Honored Matre that first antagonized the Enemy.

Along with gholas of the Tleilaxu Masters, Scytale has grown Tleilaxu females from newly discovered cells, vowing that they will never again be forced into becoming axlotl tanks, in the hopes that this will prevent the creation of a vengeful enemy such as the Honored Matres from ever occurring again, and also vowing to never again allow the Masters to corrupt the recovering Tleilaxu people.

He is also sometimes called in the Chinese tradition " Hufa Weituo Zuntian Pusa ", meaning " Honored Dharma Protector Skanda Bodhisattva ", because he is the leader of the twenty-four celestial guardian deities mentioned in the Golden Light Sutra.

Don was also Honored at The 1st ever HipHop Conference sponsored by and at The Rock & Roll Hall of Fame.

In Heretics of Dune, the Mother Superior of the Bene Gesserit Taraza ( and her immediate successor, Odrade ) manage to save one sandworm from Rakis before it is destroyed by the Honored Matres.

Seeking an alternative source of spice to break the Bene Gesserit monopoly, he meets with Uxtal, the last of the Lost Tleilaxu, hoping that he can rediscover the method of producing melange in axlotl tanks ( a secret believed lost when the Bene Tleilax were destroyed by the Honored Matres ).

Eventually, the core of the Honored Matres is destroyed according to the plan of the Bene Gesserit leader, Mother Superior Darwi Odrade.

The machines had destroyed the Honored Matre empire, and the remnants had then fled back to the Old Empire to build a new dominion.

Murbella, now in complete control of the Honored Matres and Bene Gesserit, prepares a defense against the forces of the Enemy, now identified by Other Memory to be thinking machines of Omnius, the machine overlord destroyed back in the ancient Butlerian Jihad.