Originally known as Buckingham House, the building which forms the core of today's palace was a large townhouse built for the Duke of Buckingham in 1705 on a site which had been in private ownership for at least 150 years.

The first of these was the Mile High Center, which compressed the core building into less than twenty-five percent of the total site ; the rest is adorned with an exhibition hall and fountain-dotted plazas.

A cutaway view of the proteasome 20S core particle illustrating the locations of the active site s. The α subunits are represented as green spheres and the β subunits as protein backbones colored by individual polypeptide chain.

For example, the region of the hepatitis C virus genome that encodes the core protein is highly conserved, because it contains an RNA structure involved in an internal ribosome entry site.

The complete core was assembled in Trombay before transportation to the test site.

Norfolk forms the urban core of the Hampton Roads metropolitan area, which has a population over 1. 6 million people and is the site of the world's largest naval base, Naval Station Norfolk.

The ruins of the site core of the city are located from the modern village of Copán Ruinas, which is built on the site of a major complex dating to the Classic period.

A typical site would install Ingres Client Installations on its employees PCs, and these would communicate with the Ingres Server installations on the site's core computing facility.

Also located within the county is Three Mile Island Nuclear Generating Station, site of the 1979 nuclear core meltdown.

The buildings were demolished in 1982 < ref >< cite > History of the Eastern Hospital ( at Archive in London and the M25 ) accessed: 20 October 2006 </ ref > and the site became the core of the modern Homerton University Hospital.

In 1996 the site was expanded to include the Palladian villas outside the core area, and accordingly renamed " City of Palladio and the Palladian Villas of the Veneto ".

SM-1A pressurized-water reactor reached initial criticality on 13 March 1962, and was shut down in 1972: the reactor core was removed and sent to the Savannah River nuclear site.

Today, the TMI-2 reactor is permanently shut down with the reactor coolant system drained, the radioactive water decontaminated and evaporated, radioactive waste shipped off-site, reactor fuel and core debris shipped off-site to a Department of Energy facility, and the remainder of the site is being monitored.

Streets and sidewalks of this original site, west of US 101 and the current site of the town's core, remain visible.

The " House of Scholars of Merton " originally had properties in Surrey ( in present day Old Malden ) as well as in Oxford, but it was not until the mid-1260s that Walter de Merton acquired the core of the present site in Oxford, along the south side of what was then St John's Street ( now Merton Street ).

As part of the UK government's review of websites, in 2011 the UK BAP site was ' closed ' and the core content migrated into the JNCC website.

They are categorized as actin fold proteins, sharing a common ATP binding site core that is surrounded by more variable sequences which determine substrate affinities and other properties.

In an area within a radius of the site core, peak population is estimated at 120, 000 ; population density is estimated at 265 per square kilometre ( 689 per square mile ).

In a region within a radius of the site core and including some satellite sites, peak population is estimated at 425, 000 with a density of 216 per square kilometre ( 515 per square mile ).

The construction of the core site itself is extremely similar to the layout of Naranjo ’ s Group B layout.

After the A. D. 798 date, the site core is still prosperous, yet shows less cohesion between the center and outlying areas.

By using planning, design, and construction based on sustainable values, sustainable management strives to gain LEED points by reducing footprint of the facility by sustainably planning the site with focus on these three core ideas.

If A1 repressor protein binds to the ESS, it initiates cooperative binding of multiple A1 molecules, extending into the 5 ’ donor site upstream of exon 2 and preventing the binding of the core splicing factor U2AF35 to the polypyrimidine tract.

George Meredith has said that fervor is the core of style.

The burden of these reflections is that a broader unity among the free nations is at the core of our needs.

It is hypothesized that fertility is a function of the social system when the population as a whole is considered and a function of the subsystems when the two-fold division of core families and marginal families is considered.

but this is deceptive, for the core of membership is concentrated in a single social and economic stratum.

The congregation perishes when it is no longer possible to replenish that core from the neighborhood ; ;

moreover, residential mobility is so high in metropolitan areas that churches have to recruit constantly in their core stratum in order to survive ; ;

But where the core of NATO is concerned, the Secretary of State has not only reiterated the United States' profound attachment to the alliance, `` cornerstone '' of its foreign policy, but has announced that five nuclear submarines will eventually be at NATO's disposal in European waters.

That is, when Mr. Milstein thrust straight to the core of the music, sparks flying, bow shredding, violin singing, glittering and sometimes spitting, Mr. Hendl could go along.

It is a traditional virtue in many cultures, and a core aspect of various religious traditions, though the concept of ' others ' toward whom concern should be directed can vary among cultures and religions.

The general consensus amongst scholars is that Luwian was spoken — to a greater or lesser degree — across a large area of western Anatolia, including ( possibly ) Wilusa (= Troy ), the Seha River Land ( to be identified with the Hermos and / or Kaikos valley ), and the kingdom of Mira-Kuwaliya with its core territory of the Maeander valley.

The churches of the Anglican Communion have traditionally held that ordination in the historic episcopate is a core element in the validity of clerical ordinations.

* 1945 – Physicist Harry K. Daghlian, Jr. is fatally irradiated in a criticality accident during an experiment with the Demon core at Los Alamos National Laboratory.

Admission to any of the public universities in Arizona is ensured to residents in the top 25 % of their high-school class with a GPA of 3. 0 in core competencies.

Its purpose is to initialize the Amiga hardware and core components of AmigaOS and then attempt to boot from a bootable volume, such as a floppy disk or hard disk drive.

Along with tarot divination, astrology is one of the core studies of Western esotericism, and as such has influenced systems of magical belief not only among Western esotericists and Hermeticists, but also belief systems such as Wicca that have borrowed from or been influenced by the Western esoteric tradition.

The adrenal medulla is the core of the adrenal gland, and is surrounded by the adrenal cortex.

Bufotenin, an alkaloid from some toads, contains an indole core and is produced in living organisms from the amino acid tryptophan.

When a core electron is removed, leaving a vacancy, an electron from a higher energy level may fall into the vacancy, resulting in a release of energy.

ATM is a core protocol used over the SONET / SDH backbone of the public switched telephone network ( PSTN ) and Integrated Services Digital Network ( ISDN ), but its use is declining in favour of All IP.