At the present time we do not know by what biochemical mechanism TSH acts on the thyroid, but for bio-assay of the hormone there are a number of properties by which its activity may be estimated, including release of iodine from the thyroid, increase in thyroid weight, increase in mean height of the follicular cells and increase in the thyroidal uptake of Af.

Three years later it was found in nature, although it is the least abundant element in the Earth's crust among the non-transuranic elements, with an estimated total amount of less than at any given time.

The chosen cultures overlapped in time and the indicated periods do not correspond to their estimated extends.

At the present time, approximately one third < ref > of human generated emissions are estimated to be entering the ocean.

She is one of the most successful female country artists of all time ; with an estimated 100 million in album sales, Dolly Parton is also one of the best selling artists of all time.

Flutie had estimated " an 80 percent chance " of making the drop kick, which was called to give Flutie, 43 at the time, the opportunity to make a historic kick in his final NFL game, the drop kick being his last play in the NFL.

An estimated time window is 530 – 100 BC.

Edo grew from what had been a small, little-known fishing village in 1457 to a metropolis with an estimated population of 1, 000, 000 by 1721 ( the largest city in the world at the time ).

" After his death, a friend of Armstrong estimated that 90 percent of his time was spent on litigation against RCA.

In their seminal paper in 1967 in Science, Sarich and Wilson estimated the divergence time of humans and apes as four to five million years ago, at a time when standard interpretations of the fossil record gave this divergence as at least 10 to as much as 30 million years.

" The Telegraph cited Generation X birth dates as falling into a longer time span ( 1965 – 1985 ), whilst the The Independent estimated an earlier range of birth dates ( 1963 – 1978 ) compared to other writers or researchers.

* Chapter 91 records three contending Jewish armies 200, 000 strong at Mizpeh, totaling 600, 000 men, at a time when the Roman army across the entire Empire had a total strength estimated as 300, 000.

The date of his birth remained in doubt for some time and was estimated sometime between 1863 and 1873.

At the end of 2003, GCHQ moved to a new circular HQ ( popularly known as ' the Doughnut '): at the time, it was the second-largest public-sector building project in Europe, with an estimated cost of £ 337 million.

By 1914, Hoover was an extremely wealthy man, with an estimated personal fortune of $ 4m He was once quoted as saying " If a man has not made a million dollars by the time he is forty, he is not worth much ".

This is known as the classical period of Indian history, during which time India has sometimes been estimated to have had the largest economy of the ancient and medieval world, with its huge population generating between one fourth and one third of the world's income up to the 18th century.

Today there are an estimated 700, 000 people of Irish ancestry in Argentina, approximately 15. 5 % of the Republic of Ireland's current population ; however, these numbers may be far higher, given that many Irish newcomers declared themselves to be British, as Ireland at the time was still part of the United Kingdom and today their descendants integrated into Argentine society with mixed bloodlines.

The number of combatant volunteers has been estimated at between 32, 000 – 35, 000, though with no more than about 20, 000 active at any one time.

At the time of his death in 1848, Astor was the wealthiest person in the United States, leaving an estate estimated to be worth at least $ 20 million.

His estimated net worth, if calculated as a fraction of the U. S. gross domestic product at the time, would have been equivalent to $ 110. 1 billion in 2006 U. S. dollars, making him the fourth richest person in American history .< ref name = forbes >

This turned out to be a shrewd move-he became a millionaire in a relatively short time and by the early 20th century was estimated to be worth $ 30 million.

John simply tightened his existing measures and accrued significant sums from the income of vacant sees and abbeys: one 1213 estimate, for example, suggested the church had lost an estimated 100, 000 marks ( equivalent to £ 66, 666 at the time ) to John.

The number of slaves cannot be calculated due to constant fluctuation but is estimated at 100, 000, at a time when the free employees of Krupp numbered 278, 000.

This system is most often used in US military logistics, since it makes the process of calculating estimated shipping and arrival dates easier.

The first known people were Indo-Iranians, but their date of arrival has been estimated widely from as early as about 3000 BC to 1500 BC.

It is currently estimated that among the bird species of the Pacific some 2000 species have gone extinct since the arrival of humans ( Steadman 1995 ).

Before the arrival of Europeans, an estimated 30 million people lived in South America.

Sales of " Rock Around the Clock " started slow but eventually sold an estimated 25 million copies ( per the Guinness Book of World Records ) and marked the arrival of a cultural shift.

Although population estimates vary, Father Bartolomé de las Casas, the “ Defender of the Indians ” estimated there were 6 million ( 6, 000, 000 ) Taíno and Arawak in the Caribbean at the time of Columbus's arrival in 1492.

In 1948, when the population of Bangs was 756, the arrival of senatorial candidate Lyndon Johnson by helicopter was greeted by a crowd estimated to number 700 by accompanying reporters.

The production version is expected to be based on Mk6 Golf featuring a 1. 5 L turbodiesel engine and electric motor, with estimated arrival date of 2015.

The timing of the playback is adjusted according to the atomic clock signals on the ( tapes / disk drives / fibre optic signal ), and the estimated times of arrival of the radio signal at each of the telescopes.

In 865 / 866 it escalated further on the arrival of what the Saxons called the Great Heathen Army, the size of which has been estimated at between five hundred and a thousand men, which was under the leadership of the brothers Ivar the Boneless, Ubbe and Halfdan Ragnarsson.

Neil Lincoln, chief architect, asserts that ETA is not an acronym, and otherwise means nothing, not even the well known acronym of " estimated time of arrival.

Xerxes's estimated time of arrival at Thermopylae coincided with both the Olympic Games and the festival of Carneia.

One of the more common uses is in public transportation where the movements of trains, buses, airplanes and the like can be used to generate estimated times of arrival depending on either a static timetable or through measurements on traffic intensity.

Several patents have been issued for methods or devices for calculating estimated times of arrival, including:

Prior to the arrival of Europeans, the Noongar population has been variously estimated at between 6, 000 and some tens of thousands.

" ETA SANTIAGO 17. 45 HRS STENDEC " was the last of a series of messages transmitted by Star Dust during its flight, reporting its position, altitude, and a revised estimated time of arrival in Santiago of 5. 45 PM.

An Australian coastwatcher in the Solomon Islands warned the U. S. forces of the bombers, and estimated their arrival time as 16: 00.

Abe's warship force assembled north of Indispensable Strait and proceeded towards Guadalcanal on 12 November with an estimated arrival time for the warships of early morning of 13 November.

The convoy of slower transport ships and 12 escorting destroyers, under the command of Raizo Tanaka, began its run down " The Slot " ( New Georgia Sound ) from the Shortlands with an estimated arrival time at Guadalcanal during the night of 13 November.

The arrival of the first tourist group is estimated to have occurred in February 1972.

In case of there is a possibility of tsunami after the earthquake, the JMA issues Tsunami Warning or Advisory for each region in Japan that contain estimated tsunami heights and arrival times within around 2 – 3 minutes of the quake.

A fully charged mobile phone is useful ( where reception permits ) and walkers should let someone know their route and estimated time of return or arrival (" ETA ").

An optional full-function trip computer with digital displays showed the driver " miles to empty " and ( based on driver input ) an " estimated time of arrival ", among other features.

On the Westbound platform you will find one of the common countdown timers ( found in most tube stations now ) producing an estimated time of arrival ( ETA ) for the next train, however the Eastbound platform still has one of the old signs which merely indicates the intended destination of the next train, with no indication of the ETA.