The exact mechanism of carbamazepine, gabapentin and pregabalin is similarly unclear, but these anticonvulsants are used to treat neuropathic pain with differing degrees of success.

Though there is some debate on the exact mechanism of conjugation it seems that the pili are not the structures through which DNA exchange occurs.

The exact mechanism of its action is not yet known.

The exact mechanism by which the corona is heated is still the subject of some debate, but likely possibilities include induction by the Sun's magnetic field and sonic pressure waves from below ( the latter being less probable now that coronae are known to be present in massive, hot, highly magnetic stars ).

Early epic poetry was also accompanied by music, and pitch changes associated with the accented Greek must have highlighted the melody, though the exact mechanism is still a topic of discussion.

Another research indicates there is a strong link between essential tremor in males and the amount of meat consumed, but the exact mechanism is yet unknown.

These ameliorative effects are thought to involve inhibition of glutamatergic transmission, though the numerous targets of ethanol make it difficult to determine the exact underlying mechanism.

Sleep is believed to play a key role in halting trace decay, although the exact mechanism of this is unknown.

The exact mechanism through which the production of one cytokine is increased in favor over another is not known.

The exact mechanism by which tyramine causes a hypertensive reaction is not well-understood, but it is assumed that tyramine displaces norepinephrine from the storage vesicles.

Presumably, this probing is a search for a place with easily accessible blood vessels, but the exact mechanism is not known.

The exact mechanism of this reaction is not known.

The exact mechanism behind ADE is unclear.

Although a large amount of research has been carried out, the exact mechanism of action of ECT remains elusive, and ECT on its own does not usually have a sustained benefit.

Although a large amount of research has been carried out, the exact mechanism of action of ECT remains elusive.

The exact mechanism for assigning tolerance values varies by country and industry type.

Current research directions include determining the exact mechanism of the disease, improving animal models to expedite research, clinical trials of pharmaceuticals to treat symptoms or slow the progression of the disease, and studying procedures such as stem cell therapy with the goal of repairing damage caused by the disease.

The exact mechanism of the pathogenesis of the various forms of ALD is not known.

There are numerous theories as to the exact cause and mechanism in Type 2 Diabetes.

Subsequent studies have confirmed a role for recombination in telomere maintenance by ALT ( Dunham et al., 2000 ), however the exact mechanism of this pathway is yet to be determined.

The exact mechanism for this phenomenon is unclear, but there is evidence both of impaired insulin secretion and insulin action.

Although examples of half-identical twins have been found, the exact mechanism of their conception is not well-understood, but could theoretically occur in polar body twinning where sperm cells fertilize both the ovum and the second polar body.

The exact mechanism of fertilization could not be determined but the study stated that it was unlikely to be a case of polar body twinning.

The exact chemical mechanism by which this happens is still largely unknown.

The radial spoke is thought to be involved in the regulation of flagellar motion, although its exact function and method of action are not yet understood.

The exact nature of cortisone's anti-inflammatory action remained a mystery for years after, however, until the leukocyte adhesion cascade and the role of phospholipase A2 in the production of prostaglandins and leukotrienes was fully understood in the early 1980s.

to the north-west at Ruminghem, opposite the French army under Jacques-Nompar de Caumont, duc de la Force at Zouafques ; after being joined by Imperialist reinforcements under Ottavio Piccolomini, he marched to attack La Force, and was defeated with the loss of 2, 000 men killed or captured ( action at Zouafques, exact date unknown but around 21 June ).

The exact mechanism of its anti-protozoal action is unknown ( though it may involve reactions with ubiquitin ), despite the fact that it is a basic therapeutic modality ( in concurrence with multiple antifungal medications ) when treating Acanthamoeba infections in the immunocompromised patients.

The exact mechanism of action is uncertain.

Calvin's more audacious step, in his research monograph The Cerebral Code, comes when he suggests that the pattern of action potentials in any particular neocortical minicolumn can be replicated and spread through the cortex like a piece of software code and be " played " on the millions of other minicolumns in the same way one can play a million copies of a compact disc ( CD ) on a million CD players – the key difference being that while all CD players are designed to do basically the same task, the various cortical minicolumns can all have their own unique " ruts " and the copies of the firing patterns are not exact duplicates.

When questioned about the legal basis for town action he responded, " I don't know what the exact law is ".

The exact mechanism of action is unknown, but four properties that may contribute to topiramate's antiepileptic and antimigraine efficacy include a blockage of voltage-dependent sodium channels, an augmentation of gamma-aminobutyrate acid activity at some subtypes of the GABA-A receptors, antagonism of AMPA / kainate subtype of the glutamate receptor, and inhibition of the carbonic anhydrase enzyme, particularly isozymes II and IV.

By then, however, the protest action seemed to be having some success, with Sheehan, the Native Minister, telling Parliament on 23 July: " I was not aware ... what the exact position of those lands on the west coast was.

Though the exact reason for her action is unknown, according to Santōka ’ s diaries his mother had finally reached the point where she could no longer live with her husband ’ s philandering.

Her declaration bears the same outline and context as the Declaration of the Rights of Man and the Citizen, but Gouges either changes the word “ man ” to “ woman ” or adds “ for both women and men .” In article II, the resemblance is exact to the previous declaration except that she adds “ especially ” before “ the right to the resistance of oppression ”, emphasizing again how important it is to her to end the oppression of women, and that the government should recognize this and take action.

Scotty's operation of the Enterprise transporter system inspired the catchphrase " Beam me up, Scotty ", which gained currency in popular culture beyond Star Trek fans, even though the exact phrase is never spoken in any live action episode or film in that exact way, although it is used frequently in the animated series.

Almost a third, about 6, 000, perished in action ( the exact number is uncertain as official data includes non-native soldiers who died in Tyumen's hospitals ).

The exact mechanism of action of CES remains unclear but it is proposed that CES reduces the stress that underpins many emotional disorders.

The exact action of these pedals and levers — which strings are affected — can be set by the player to their preference.

The exact action being difficult to see, led to considerable speculation on the method used.

In such cases, the Tier I EIS would analyze the potential socio-environmental impacts along a general corridor, but would not identify the exact location of where the action would occur.

Following the Tier I ROD, the approved Tier I area is further broken down into subareas, and a Tier II EIS is then prepared for each subarea, that identifies the exact location of where the proposed action will take place.

Aminoglycosides have several potential antibiotic mechanisms, some as protein synthesis inhibitors, although their exact mechanism of action is not fully known: