While it is occasionally used recreationally for its hallucinogenic properties, the experiences are often extremely mentally and physically unpleasant, and frequently physically dangerous, so repeated use is rare.

* April 22 – Albert Hofmann writes his first report about the hallucinogenic properties of LSD ( which he first synthesized in 1938 ).

Mescaline is produced when products of natural mammalian catecholamine-based neuronal signaling such as dopamine and serotonin are subjected to additional metabolism via methylation, and its hallucinogenic properties stem from these very structural similarities.

Both classes of these drugs are agonists at the 5-HT < sub > 2 </ sub > receptors ; this is thought to be the central component of their hallucinogenic properties.

However the tropane alkaloids which are responsible for both the medicinal and hallucinogenic properties are fatally toxic in only slightly higher amounts than the medicinal dosage, and careless use often results in hospitalizations and deaths.

Across the Americas, other indigenous peoples such as the Algonquin, Cherokee, Marie Galente and Luiseño also utilized this plant in sacred ceremonies for its hallucinogenic properties.

Amanita muscaria is noted for its hallucinogenic properties, with its main psychoactive constituent being the compound muscimol.

Aztec priests in Mexico were also known to use the plant's hallucinogenic properties.

Instead, the Psilocybe semilanceata, being the only psilocybin-containing mushroom common in Slavic countries, is sought after for its hallucinogenic properties, the latter being more desirable with fewer side effects than those of A. muscaria.

Antagonists of the NMDA receptor are used as anesthetics for animals and sometimes humans, and are often used as recreational drugs due to their hallucinogenic properties, in addition to their unique effects at elevated dosages such as dissociation.

The psilocybin molecule is indirectly responsible for the hallucinogenic properties of the Psilocybe genus.

In addition to its hallucinogenic properties, caapi is used for its healing properties as a purgative, effectively cleansing the body of parasites and helping the digestive tract.

In some regions, mugwort thins the blood, while in another region, it is claimed to have hallucinogenic properties, causing some to pass out from direct skin contact ( dermal absorption ) with the active chemicals.

Amanita muscaria ( fly agaric ) is another mushroom having hallucinogenic properties that has not been thoroughly studied.

Fly agaric is mildly toxic at high dosages and is said to have, in addition to its hallucinogenic properties, the ability to increase strength and endurance.

A. muscaria, the " Alice in Wonderland " mushroom, is known for the toxic / hallucinogenic properties caused by muscimol, but A. pantherina and A. gemmata also contain the same compound.

Some of the entries in the tryptamines category may actually be hallucinogenic tryptamines, but information on their properties and effects is currently lacking.

The plant is a rare example of a plant whose hallucinogenic properties were not recognized until recent times.

It is classified as a schedule III depressant by the DEA, although the substance has hallucinogenic / psychedelic properties.

Traditionally used in healing and initiation ceremonies by followers of the West-African Bwiti religion, the drug has stimulant properties in low doses and can induce a hallucinogenic dream-like state in higher doses.

Myristicin in the essential oil is probably the agent responsible for the hallucinogenic properties of nutmeg oil.

The program has been described as " psychedelic ", and Gosper joked about keeping it a secret from the Food and Drug Administration ( FDA ) due to its " hallucinogenic properties ".

It refers to the Christmas vine ( Turbina corymbosa ), a species of morning glory whose seeds contain ergine and have hallucinogenic properties.

The beans ( sometimes called seeds ) and falling leaves are hallucinogenic and are toxic to cattle.

The effects of these mushrooms can be hallucinogenic, but are mostly depressant.

A variety of techniques are used by Number Two to try to extract information from Number Six, including hallucinogenic drug experiences, identity theft, mind control, dream manipulation, and various forms of social indoctrination.

She indicates that when people, after having been immunized against snake-bite, are bitten by a venomous snake, particularly by krait, cobra or another elapids, they experience an emotional and mental state that has been compared to the effects of hallucinogenic substances.

Ceiba insignis and Ceiba speciosa are added to some versions of the hallucinogenic drink Ayahuasca.

Made of a nearly indestructible material, these containers are commonly called " grails " and produce food, drink, pieces of cloth, and luxury items, such as alcohol, tobacco, marijuana ( and lighters for some ), hair care utensils, makeup, and a hallucinogenic chewing gum which is known as " dreamgum.

* Thomas Pynchon's three novels Gravity's Rainbow, Mason & Dixon and Against the Day are historical, and they variously contrast outrageous personal, subjective, hallucinogenic or even supernatural events with very real, well-researched accuracies from the past.

The position and expression of the body, in combination with the very clear representations of hallucinogenic plants which are known to have been used in sacred contexts by the Aztec support this interpretation.

Other possible causes and / or signs of association with the syndrome are migraines, use of hallucinogenic drugs, and infectious mononucleosis.

While hallucinogenic mushrooms ( e. g. Psilocybin mushrooms ) are occasionally consumed for recreational or religious purposes, they can produce severe nausea and disorientation, and are therefore not commonly considered edible mushrooms.

To the non-shaman they are normally invisible, and even shamans can perceive them only under the influence of natema ( a hallucinogenic drink ).

Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances.

At sub-anesthetic doses, dissociatives alter many of the same cognitive and perceptual processes affected by other hallucinogenic drugs such as mescaline, LSD, and psilocybin ; hence they are also considered hallucinogenic, and psychedelic.

Additionally, many visionary artists of this type are actively engaged in spiritual practices, and some have drawn inspiration from hallucinogenic intoxication.

The effects of the drug at larger dosages ( 12-30 + mg ) are often described as combining psychedelic or hallucinogenic effects typical of drugs such as LSD with the empathogenic or entactogenic effects of drugs such as MDMA ( ecstasy ).

The report concludes that a small percentage of sightings that can not be easily explained are caused by atmospheric plasma phenomenon similar to ball lightning ; Magnetic and other energy fields produced by these " buoyant plasma formations " are responsible for the appearance of so-called " Black Triangles " as well as having hallucinogenic effects on the human mind, inducing experiences of Close Encounters.

" – While the toxic / hallucinogenic fly agaric is usually bright red or yellow, the deadly destroying angel is an unremarkable white, and the deadly Galerinas are brown.

Since most hallucinogenic drugs are mostly visual, HPPD usually has a visual manifestation.