Of the inbred strains that have been created, the two that are still used with any frequency are, following Sewall Wright's designations, " Strain 2 " and " Strain 13 ".

Doubled haploid ( DH ) plants have the potential to save much time in the development of inbred lines.

It has been suggested that he suffered from the endocrine disease acromegaly, or his inbred lineage may have led to a combination of rare genetic disorders such as combined pituitary hormone deficiency and distal renal tubular acidosis.

But he had an inbred " revolt from fact " which would have estranged him from the actualities of any age.

Some extreme cases of cyclopia have been documented in inbred farm animals ( horses, sheep, pigs, and sometimes chickens ).

When George retorts that his family are not inbred, Blackadder replies, " Come on, somewhere outside Saffron Walden there's an uncle who's seven feet tall with no chin and an Adam's apple that makes him look as though he's constantly trying to swallow a ballcock ", to which George replies, " I have not got any uncles like that!

It has been suggested that he suffered from the endocrine disease acromegaly, or his inbred lineage may have led to a combination of rare genetic disorders such as combined pituitary hormone deficiency and distal renal tubular acidosis.

Animal models serving in research may have an existing, inbred or induced disease or injury that is similar to a human condition.

To add some confusion, the term " hybrid inbred " also applies to hybrids that are made from selected inbred lines that have certain desired characteristics ( see inbreeding ).

Many studies have reported the inbred populations could be susceptible to diseases due to a weakening immune system, possibly causing their sperm to be deformed, leading to infertility.

All have inbred knowledge called Memory which tells them who they are, and what their role in the Hill is.

Furthermore, some scientists have suggested that heirloom tomatoes are no more natural than commercial ones, and that many are simply " inbred " tomatoes.

Many inbred strains exist, as well as lines selected for particular traits, often of medical interest, e. g. body size, obesity, muscularity.

The standard method of breeding inbred wheat cultivars is by crossing two lines using hand emasculation, then selfing or inbreeding the progeny.

* Three-way cross hybrids — result from the cross between one parent that is an F1 hybrid and the other is from an inbred line.

An individual who results from inbreeding is referred to as inbred.

Triticale is essentially a self-fertilizing, or naturally inbred, crop.

Undefeated racehorse, Frankel, is inbred 3 x 4 to Northern Dancer, meaning that Northern Dancer appears once in the third generation and once in the fourth generation of his pedigree.

The reason is purging selection, most efficient in populations that are strongly but not dangerously inbred.

The crude locals are unimpressed by the " city boys ;" it is also implied that some of the locals are inbred.

Since a molecular genetic test for the ridge gene does not exist, heterozygotes are detected by mating the animal in question to either known heterozygotes or known homozygous recessives ( other methods exist such as mating to offspring, but result in inbred offspring ) and a heterozygote is detected when a ridgeless pup is born.

In captivity, the species is very inbred.

For most purposes this is sufficient to be considered an inbred strain ( compare to identical twins or clones which are 100 % genetically identical ).

The inhabitants are depicted as inbred, uneducated, and very superstitious, while the town itself is described as economically poor with many decrepit and abandoned buildings.

When Lieutenant George is injured and sent to the military infirmary, Captain Blackadder visits him with the ulterior motive of getting his hands on the food sent to George by his family, whom Blackadder refers to as a " collection of inbred mutants ".

The value for F is found by solving the equation for F using heterozygotes in the above inbred population.

A consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain via a series of marker-assisted backcrosses.

To produce hybrid seed, elite inbred varieties with well documented and consistent phenotypes ( such as yield ) are crossed and the resulting hybrid seed is collected.

However, the modern hybridization process, where one inbred line of corn is crossed with another, developed from this early work in cross breeding.

This hybrid seed is produced by crossing two inbred lines by planting a row of one inbred variety followed by several rows of a second variety.

It may also be called entire sanctification, in which the heart of the believer is cleansed from inbred sin by the infilling of the Holy Spirit.

There has been speculation that, though Toplady was a Calvinist, the words, " Be of sin the double cure, Save from wrath, and make me pure ," suggest that he agreed with the teachings of the Methodist preacher under whom he received his religious conversion, and of his contemporary, John Wesley, who taught the “ double cure ,” in which a sinner is saved by the atonement of Jesus, and cleansed from inbred sin by the infilling of the Holy Spirit.

Roughly speaking, the coefficient of relationship approaches a value of 1 for individuals from a completely inbred population, and approaches a value of 0 for individuals with arbitrarily remote common ancestors.

After the war, as the frontier pushed further west, the Appalachian country retained its frontier character, and the people themselves came to be seen as backward, quick to violence, and inbred in their isolation.

However, because the increased proportion of deleterious homozygotes exposes the allele to natural selection, in the long run its frequency decreases more rapidly in inbred population.

This usually will include characteristics such as short life-cycle, techniques for genetic manipulation ( inbred strains, stem cell lines, and methods of transformation ) and non-specialist living requirements.

These eggs then hatched into chickens that inbred to produce a living population.

F1 hybrid wheat cultivars should not be confused with the standard method of breeding inbred wheat cultivars by crossing two lines using hand emasculation, then selfing or inbreeding the progeny many ( ten or more ) generations before release selections are identified to be released as a variety or cultivar.

Regardless, it's clear that Fry's just very inbred.

Some biologists even believe that they are too inbred to flourish as a species.

Neither her parents nor her grandparents were closely related to each other, making Maria Theresa one of few members of the House of Habsburg who were not inbred.

Here, Blackstone characterized the Press as an inbred institution that had given up all pretence of serving scholarship, " languishing in a lazy obscurity ... a nest of imposing mechanics.

" Mark Arm claimed that the isolation meant, " this one corner of the map was being really inbred and ripping off each other's ideas.

In plant breeding, inbred lines are used as stocks for the creation of hybrid lines to make use of the effects of heterosis.

Island species are often very inbred, as their isolation from the larger group on a mainland allows for natural selection to work upon their population.

The increase in frequency of birth defects often attributed to inbreeding results directly from an increase in the frequency of homozygous alleles inherited by the offspring of inbred couples.

In studies using genetic knock-out techniques in inbred mice, male mice that lacked a functional aromatase enzyme displayed a marked reduction in aggression.

A hairless and immunodeficient breed was the result of a spontaneous genetic mutation in inbred laboratory strains from the Hartley stock at the Eastman Kodak Company in 1979.

Not all pedigreed cats are excessively inbred, however ; in the past, this was the case with some breeds, before the modern understanding of genetics was widely circulated.