It is preferred that benzodiazepines be taken intermittently and at the lowest effective dose.

Using the lowest effective dose for the shortest period of time minimizes the risks to the unborn child.

Preferably they should be prescribed for only a few days at the lowest effective dose, and avoided altogether wherever possible in the elderly.

To minimise GI ADRs, it is prudent to use the lowest effective dose for the shortest period of time — a practice that studies show is often not followed.

Models predict that the most effective way to achieve this, using a drug with the lowest possible dose, is to find a drug that binds to fibril ends and blocks them from growing any further.

Specialty professional organizations recommend that patients take the lowest effective dose possible to achieve the desired therapeutic result when using proton pump inhibitors to treat gastroesophageal reflux disease long-term.

Until more becomes understood about the possible risks, women who elect to use hormone replacement therapy are generally well advised to take the lowest effective dose of hormones for the shortest period possible, and to question their doctors as to whether certain forms might pose fewer dangers of clots or cancer than others.

Thus it would seem that the prescription of oral estrogen therapy should be at the lowest available dose to minimise effects on circulating estrone sulphate and SHBG.

It is preferred that hypnotics be prescribed for only a few days at the lowest effective dose and avoided altogether wherever possible in the elderly.

( Other sources give a much higher oral LD < sub > Lo </ sub > ( lowest published lethal dose ) of 600 mg / kg.

Medical societies recommend that when a doctor and patient decide on a plan for treating GERD long-term with acid-suppression drugs that the lowest possible effective dose be used.

Copperhead venom has an estimated lethal dose of around 100 mg, and tests on mice show its potency is among the lowest of all pit vipers, and slightly weaker than that of its close relative, the cottonmouth.

Primary prevention of tardive dyskinesia is achieved by using the lowest effective dose of a neuroleptic for the shortest time.

The lowest known lethal dose, derived from an individual case of poisoning, is abbreviated LCLo.

Cholinesterase inhibition was observed at all dose levels tested, the lowest of which was 1. 5 mg / kg.

The lowest effective dose should be used.

The lowest published lethal dose is 101 mg / kg body weight in adult humans, ( or 7. 07 grams for a 70-kg adult ).

The highest concentrations of oxiracetam is found in the septum pellucidum, followed by the hippocampus, the cerebral cortex and with the lowest concentrations in the striatum after a 200 mg / kg oral dose given to rats.

The lowest dose to cause symptoms of nausea is about 25 mg solanine for adults, a life-threatening dose for a regular-weight adult ranges about 400 mg solanine.

Flurazepam is best used for a short time period and at the lowest possible dose to avoid complications associated with long term use.

The lowest doses of ketamine and tiletamine that produced neurotoxic changes visible by light microscope 4 hours post dose were 40 ( mg / kg sc ) and 10 ( mg / kg sc ), respectively.

Care should be taken in choosing an appropriate hypnotic drug and if drug therapy is initiated it should be initiated at the lowest possible dose to minimise side effects.

Horses have the lowest tolerance, with a lethal dose of 200 – 400 mg / kg body weight, but cattle, pigs, and other livestock are only slightly less vulnerable.

Preferably they should be prescribed for only a few days at the lowest effective dose and avoided altogether wherever possible in the elderly.

In 1998, 21 % of adults tested at a literacy level of 1, one being the lowest, compared to the national average of 22 %.

Bottom Up Testing is an approach to integrated testing where the lowest level components are tested first, then used to facilitate the testing of higher level components.

The Ottawa River Risk Assessment, a report published in 2000, tested the water of the lower section of the Ottawa River, and found many chemicals in the water with an hazard quotient greater than 1 ( from highest to lowest concentration ): lead, aluminum, PCBs, manganese, iron, DDT, thallium, selenium, chromium, nickel, cadmium, cyanide, and zinc.

He developed a carbon coating that showed the lowest coefficient of friction, less than 0. 001, when tested in a dry nitrogen atmosphere.

The big question that engineers and workers were tested for their ability to perform a superstructure-a false ellipse, measuring the major axis of 275 meters and the lowest 217 meters-using conventional equipment.

This means that a 16 year old child who has mental retardation may be tested using the WISC-IV so that the clinician may see the floor of their knowledge ( the lowest level ).

For example, to move ( as the score requires ) from the lowest F-major register up to a barely audible N minor in four seconds, not skipping, at the same time, even one of the 407 fingerings, seems a feat too absurd to consider, and it is to the flautist's credit that he remained silent throughout the passage.

For example, the orbital 1s < sup > 2 </ sup > ( pronounced " one ess two ") has two electrons and is the lowest energy level ( n

He and his peers were acutely aware that they were one step above the lowest on the socio-economic ladder, i. e. the black community.

As of April 2010, the CIA factbook described the telephone system as “ primitive ” with “ one of the lowest ” telephone densities in the world and “ increasing.

Berkelium is relatively soft and has one of the lowest bulk moduli among the actinides, at about 20 GPa ( 2Pa ).

Bidding is based on the premise that the lowest contract available to bidders starts with the proposition to take seven tricks, i. e. one cannot contract to make less than seven tricks.

The Old French term crossed into English around 1300, referring to one belonging to the lowest stage of knighthood.

Anglo-Irish relations hit one of their lowest ebbs, with the Irish Minister for Foreign Affairs, Patrick Hillery, going specially to the United Nations in New York to demand UN involvement in the Northern Ireland " Troubles ".

The per capita income of the CAR is often listed as being around $ 300 a year, said to be one of the lowest in the world, but this figure is based mostly on reported sales of exports and largely ignores the more important but unregistered sale of foods, locally-produced alcohol, diamonds, ivory, bushmeat, and traditional medicines, for example.

Nevertheless, Colombia has one of the lowest ratios of paved roads per inhabitant in Latin America.

This seven-judge procedure has been modified as of the 2012 London Olympics: rather than eliminating one high and one low award and then reducing the total by as in previous international events, the two highest awards and the two lowest are disregarded, leaving three to be summed and multiplied by the difficulty rating.

The Diesel engine has the lowest specific fuel consumption of any large internal combustion engine employing a single cycle, 0. 26 lb / hp. h ( 0. 16 kg / kWh ) for very large marine engines ( combined cycle power plants are more efficient, but employ two engines rather than one ).

Despite such challenges to keep public finances in balance, El Salvador still has one of the lowest tax burdens in the American continent ( around 11 % of GDP ).

In 2010, just 0. 75 percent of the population were using the Internet, one of the lowest rates in the world.

After the severe economic troubles of the early 1990s, brought on by a drop in the vital fish catch and poor management of the economy, the Faroe Islands have come back in the last few years, with unemployment down to 5 % in mid-1998, and holding below 3 % since 2006, one of the lowest rates in Europe.

The Faroes have one of the lowest unemployment rates in Europe, but this is not necessarily a sign of a recovering economy, as many young students move to Denmark and other countries once they are finished with high school.

The sellout streak is driven by the Red Sox's loyal fan base, the success of the Red Sox during this time ( a winning record over nine seasons, during which time the team achieved at least 90 wins seven times, six playoff appearances and two World Series Championships ), and Fenway Park's low capacity: fourth lowest in seating capacity and second lowest in total of all MLB stadiums ; it is one of the seven MLB ballparks that cannot accommodate at least 40, 000 spectators.

As a result of very stringent controls, gun ownership in Poland is the lowest in the European Union, at one firearm per 100 citizens.

Hong Kong has one of the world ’ s lowest birth rates — 0. 9 per woman of child-bearing age, far below the replacement rate of 2. 1.

The " ground state ", i. e. the state of lowest energy, in which the electron is usually found, is the first one, the 1s state ( principal quantum level n

From the last Eurostat data, Italian per capita GDP at purchasing power parity remains approximately equal to the EU average, while the unemployment rate ( 8. 5 %) stands as one of the EU's lowest.

It is a tailored garment that is wrapped around the wearer's body at the natural waist ( between the lowest rib and the hip ) starting from one side ( usually the wearer's left ), around the front and back and across the front again to the opposite side.

Dunst explained that Tuesday is " not a holiday, and United States is one of the lowest democratic countries in voter turnout.