The general acceptance of the idea of governmental ( i.e., societal ) responsibility for the economic well-being of the American people is surely one of the two most significant watersheds in American constitutional history.

As symptomatic of the common man's malaise, he is most significant: a liberal and a Catholic, elected by the skin of his teeth.

Of all the Whig tracts written in support of the Succession, The Crisis is perhaps the most significant.

One of the most significant advancements in design of plastics signs is the so-called trans-illuminated billboard, now being produced by several large sign manufacturers such as Advance Neon Sign Co., Los Angeles, and Industrial Electric Inc., New Orleans, La..

Other than this very significant result, most of the information now available about the radio emission of the planets is restricted to the intensity of the radiation.

Statistically, the most significant data have been collected from the sensors on 1958 Alpha ( Explorer 1 ), 1958 Delta 2 ( Sputnik 3 ), and 1959 Eta ( Vanguard 3 ).

Such conversation quickly reveals an ethically significant ambivalence in the self-images held by most realtors.

Aristotle not only studied almost every subject possible at the time, but made significant contributions to most of them.

The group of elements is more diverse than the lanthanides and therefore it was not until 1945 that Glenn T. Seaborg proposed the most significant change to Mendeleev's periodic table, by introducing the actinides.

Alpha, both as a symbol and term, is used to refer to or describe a variety of things, including the first or most significant occurrence of something.

Among Poirot's most significant personal attributes is the sensitivity of his stomach:

In the Southwest, mountain ranges, rivers and, most obviously, the Grand Canyon can be significant barriers for human communities, likely reducing the frequency of contact with other groups.

The lives of numerous abbots make up a significant contribution to Christian hagiography, one of the most well-known being the Life of St. Benedict of Nursia by St. Gregory the Great.

The basic design remained unchanged for centuries, with the most significant changes being to the overall proportions, and a move from wooden stocks to those of iron.

Historic Swabia was eventually replaced by today's Baden-Württemberg, but it had been the most significant territory of mediaeval Alamannia, comprising all Germania Superior and territory east to Bavaria.

Hence, if a dish contains significant amounts of any of these ingredients, it has most likely been Americanized.

The most significant moderate proposal was the Fourteenth Amendment, also written by Trumbull.

The most significant of these is the story about Ambrosius, Vortigern, and the two dragons beneath Dinas Emrys, " Fortress of Ambrosius " in Chapters 40 – 42.

On the subject of charity Andrew Carnegie's actions diverged in the most significant and complex manner from Herbert Spencer's philosophies.

Although the hardware is limited to four separate sound channels, software such as OctaMED uses software mixing to allow eight or more virtual channels, and it was possible for software to mix two hardware channels to achieve a single 14-bit resolution channel by playing with the volumes of the channels in such a way that one of the source channels contributes the most significant bits and the other the least.

Naamani Tarkow has written: " If one is to make sweeping statements, one may say that, save Magna Carta ( more truly, its implications ), the Act of Settlement is probably the most significant statute in English history ".

Dunn, who was tied for the major league lead with 32 home runs, was expected to provide a significant boost to an offense that has struggled to score runs for most of the season.

Sunday family dinner is considered the most significant meal of the week, whose highlights often include asado or pasta.

From the 1960s through the 1980s, " by far the most significant developments in the design and construction of acoustic guitars " were made by the Ovation Guitar Company.

Moreover, these combination analgesics can often result in significant adverse events, including accidental overdoses, most often due to confusion which arises from the multiple ( and often non-acting ) components of these combinations.

The grocery the youth worked for soon tired of his depressing effect on customers, most of whom were sufficiently neurotic without the threat of incubi, and let him go.

With the signing of the Treaty of Alfred and Guthrum, an event most commonly held to have taken place around 880 when Guthrum ’ s people began settling East Anglia, Guthrum was neutralised as a threat.

He was born in Antwerp, where he started his career, but he spent most of it in Middelburg ( 1587 – 1613 ), where he moved with his family because of the threat of religious persecution.

Perhaps Capp's most popular creations were the Shmoos, creatures whose incredible usefulness and generous nature made them a threat to civilization as we know it.

According to the Foreign & Commonwealth Office, " Problems associated with drug trafficking are potentially the most serious threat to stability in the BVI ".

Although the disease is not a threat to humans the most vulnerable common domestic ruminants in the UK are cattle, goats and, especially, sheep.

The previous year had been one of success for France and her allies, most particularly on the Danube, where Marshal Villars and the Elector of Bavaria had created a direct threat to Vienna, the Habsburg capital.

The presence of Roman forces in the Danube delta was seen as a major threat by all the neighbouring transdanubian peoples: the Peucini Bastarnae, the Sarmatians and, most importantly, by Burebista ( ruled 82-44 BC ), king of the Getae.

There the threat to its integrity was the most pronounced, and the need for reforms was most evident.

Physical coercion is the most commonly considered form of coercion, where the content of the conditional threat is the use of force against a victim, their dear ones or property.

The most obvious example is blackmail, where the threat consists of the dissemination of damaging information.

Smallpox was a serious threat in colonial America, most devastating to Native Americans, but also to Anglo-American settlers.

#“ The educational situation which most effectively promotes significant learning is one in which ( a ) threat to the self of the learner is reduced to a minimum and ( b ) differentiated perception of the field is facilitated ” ( Rogers, 1951 ).

Tensions between the superpowers increased during this time, when Carter placed trade embargoes on the Soviet Union and stated that the Soviet invasion of Afghanistan was " the most serious threat to the peace since the Second World War.

Charles Xavier compiled a list of the Earth's most powerful mutants and plans on how to defeat them if they become a threat to the world.

Of these, the Sarmatians and the Dacians posed the most formidable threat.

In the first two series Mike's position is constantly under threat from senior reporter Brooke Vandenberg, who has a better press profile, but by the last series he has been cemented as one of the network's most valuable stars and considerably more effort is made to pander to his whims.

Despite most Guatemalans ' attachment to the original ideals of the 1944 uprising, some private sector leaders and the military began to believe that Arbenz represented a Communist threat and supported his overthrow, hoping that a successor government would continue the more moderate reforms started by Arevalo.

Perhaps most important for determining the success of both the Greens and the SPD was the increasing threat of war in Iraq, which was highly unpopular with the German public, and helped gather votes for the parties which had taken a stand against participation in this war.

The Carlists were the most immediate threat, launching a violent insurrection after their poor showing in the 1872 elections.

To the Orthodox Church and most princes, the fanatical Northern Crusaders seemed a greater threat to the Russian way of life than the Mongols.

Although it is largely disputed whether Strauss himself was a historicist, he often indicated that historicism grew out of Christianity and was a threat to civic participation, a belief in human agency, religious pluralism, and, most controversially, an accurate understanding of the classical philosophers and religious prophets themselves.

Various kits exist, but one of the most famous names is the Volkswagen Beetle-based " Wombat " ( previously called a HummBug, until the threat of a lawsuit from General Motors forced them to change both the name and the design of the grill to make it look less like the real thing ).