Comparisons between immunomodulators ( all but mitoxantrone ) show that the most effective is natalizumab, both in terms of relapse rate reduction and halting disability progression.

Disease-modifying treatments reduce the progression rate of the disease, but do not stop it.

Similarly, a trial using vitamin E alone found that vitamin E supplementation produced no change in the risk of developing cataracts or the rate of progression of existing cataracts.

In a 1998 study, vitamin E supplements had no effect on the rate of progression.

He also computed the rate of growth of insect populations and noted that there must be natural checks since the theoretical population numbers achieveable by geometric progression were not matched by observations of actual populations.

The technique can record a snapshot of the degree and extent of the deformation as a benchmark for assessing its rate of progression.

Interferons have been shown to produce about a 18 – 38 % reduction in the rate of MS relapses, and to slow the progression of disability in MS patients.

The technique involves a step-by-step progression that begins from physiological conditioning, such as muscle relaxation, breathing control and heart rate control.

This classifies both the rate of progression and severity of disease.

Since each type of molecule has a different rate of progression, the various components of the analyte mixture are separated as they progress along the column and reach the end of the column at different times ( retention time ).

While it is impossible to compare results across different clinical trials, the older generation drugs, i. e. interferons and glatiramer acetate, are generally acknowledged as demonstrating about a 30-35 % decrease in relapse rate vs. placebo ; and only two drugs have been shown to decrease the progression of disability, but again only by around 20-40 %.

Although the use of ACE inhibitors and ARBs represents the current standard of care for patients with CKD, patients progressively lose kidney function while on these medications, as seen in the IDNT and RENAAL studies, which reported a decrease over time in estimated glomerular filtration rate ( an accurate measure of CKD progression, as detailed in the K / DOQI guidelines ) in patients treated by these conventional methods.

The objective of radiotherapy is to stop disease progression and has a documented success rate of 85 %.

Text progression pauses at these points, and depending on the choices that the player makes, the affection rate of the heroine associated with the event will either increase, decrease, or remain the same.

The rate of progression of the cell cycle is further adjusted by additional signals arising from cellular sensors that monitor environmental conditions ( for example, nutrient levels and the oxygen level ) or the internal cell status ( for example, presence of DNA damage ).

There is no specific time requirement as with the core syllabus, as progression in the advanced phase is down to rate at which the student pilot is able to achieve the desired results.

The pattern of symptom development resembles that of Duchenne muscular dystrophy, but with a later, and much slower rate of progression.

The only way to know for sure if a nerve injury is in fact neurotmesis is to allow for the normal progression of nerve regeneration to take place ( nerves regenerate at a rate of approximately 2-4mm / day proximal to the lesion ) and if after that time there is still resound muscle paralysis and degeneration in these areas then it is likely to have been a neurotmesis injury.

Heart rate rises with progression of colic, in part due to pain, but mainly due to decreased circulating volume, decreased preload, and endotoxemia.

Furthermore, once nephropathy develops, the greatest rate of progression is seen in patients with poor control of their blood pressure.

The pattern and rate of progression of cerebral atrophy depends on the disease involved.

The district includes eight National Blue Ribbon Schools, which have achieved a 97 % graduation rate and more than 75 % progression to post-secondary education.

PRP has a varied clinical progression and a varied rate of improvement.

Text progression pauses at these points, and depending on the choices that the player makes, the affection rate of the heroine associated with the event will either increase, decrease, or remain the same.

As implemented on the VIC-20 and Commodore 64, CBM DOS could transfer only about 300 bytes per second-compare the 300 baud data rate of the Commodore cassette storage system-which translated to about 20 minutes to copy one disk — 10 minutes of reading time, and 10 minutes of writing time.

Passwords that are used to generate cryptographic keys ( e. g., for disk encryption or Wi-Fi security ) can also be subjected to high rate guessing.

The torque-free precession rate of an object with an axis of symmetry, such as a disk, spinning about an axis not aligned with that axis of symmetry can be calculated as follows:

Simulations have shown that the presence of a binary companion can actually improve the rate of planet formation within stable orbital zones by " stirring up " the protoplanetary disk, increasing the accretion rate of the protoplanets within.

Like any non-compressed, lossless format, it uses much more disk space than MP3 — about 10MB for one minute of stereo audio at a sample rate of 44. 1 kHz and a sample size of 16 bits.

This waiting for the disk to spin around to the right spot slows the data transfer rate.

Lossy data compression involves discarding some of the media's data so that it becomes simplified enough to be stored within the desired disk space ( known as a data rate or bit rate for media that is streamed ).

Spectroscopically, the outer ring's expansion rate is 40 km · s < sup >− 1 </ sup >, and about 32 km · s < sup >− 1 </ sup > for the inner disk.

The mass of the disk around a classical T Tauri star is about 1 – 3 % of the stellar mass, and it is accreted at a rate of 10 < sup >- 7 </ sup > to 10 < sup >- 9 </ sup > solar masses per year.

The major constraints on any hard disk recording system are the disk size, transfer rate, and processor speed.

* A 20 MB hard disk drive that was twice as fast ( seek times of about 40 msec ) as the PC XT's 10 MB drive, although the early drives manufactured by Computer Memories ( CMI ) had a 25 – 30 % failure rate after one year.

The outer tracks of a hard disk have a higher transfer rate than the inner tracks, therefore placing files on the outer tracks increases performance.

Typically the rate at which new stars are formed in pseudobulges is similar to the rates at which stars form in disk galaxies.

With the disk spinning at a constant rate, each bit is given an equal time period, a " data window ," for the magnetic signal that represents that bit, and the flux reversal, if any, occurs at the start of this window.

The most common spooling application is print spooling: documents formatted for printing are stored usually into an area on a disk and retrieved and printed by a printer at its own rate.

It is defined as the ratio between the mass flow rate of air drawn through a fan disk which bypasses the engine core ( un-combusted air ), to the mass flow rate passing through the engine core which is involved in combustion to produce mechanical energy.

The sound quality during live playback ( as opposed to saving the generated sound to disk ), assuming that the CPU could cope with the sampling rate, was imposed by the quality of the sound card.

Let there be an observer C on a disk rotating in the xy plane at a coordinate angular rate of and who is at a distance of r from the center of the disk with the center of the disk at x = y = z = 0.