* Superantigen-A class of antigens that cause non-specific activation of T-cells, resulting in polyclonal T cell activation and massive cytokine release.

Following activation of adenylate cyclase, the resulting cAMP acts as a second messenger by interacting with and regulating other proteins such as protein kinase A and cyclic nucleotide-gated ion channels.

Catalytic reactions have a lower rate-limiting free energy of activation than the corresponding uncatalyzed reaction, resulting in higher reaction rate at the same temperature.

The hormone binds to the receptor protein, resulting in the activation of a signal transduction mechanism that ultimately leads to cell type-specific responses.

A good example is the blood clotting cascade whereby an initial event triggers a cascade of sequential proteolytic activation of many specific proteases, resulting in blood coagulation.

The p21 gene contains several p53 response elements that mediate direct binding of the p53 protein, resulting in transcriptional activation of the gene encoding the p21 ( WAF1 ) protein.

In Felty's syndrome, Kupffer cell activation is so marked that the resulting increase in hepatocyte activity is associated with nodular hyperplasia of the liver, which may be palpably enlarged.

This leads to sympathetic nerve activation, resulting in renal afferent arteriolar vasoconstriction and renin secretion through β 1-receptors.

The process of vision relies on the light-induced isomerisation of the chromophore from 11-cis to all-trans resulting in a change of the conformation and activation of the photoreceptor molecule.

Damage or low activation in this area can reduce an individual's ability to filter out distracting stimuli, ultimately resulting in poorer organization, a loss of attention and increased procrastination.

Membrane binding may also promote rearrangement, dissociation, or conformational changes within many protein structural domains, resulting in an activation

Fenitrothion was found to completely inhibit dihydrotestosterone-dependent human androgen receptor activation, resulting in reduced weights of seminal vesicles and the ventral prostate.

Antibodies that bind to antigens can be recognised by FcϒRIII ( CD16 ) receptors expressed on NK cells resulting in NK activation, release of cytolytic granules and consequent cell apoptosis

The resulting brain activation can be presented graphically by color-coding the strength of activation across the brain or the specific region studied.

However, the main reason that temperature increases the rate of reaction is that more of the colliding particles will have the necessary activation energy resulting in more successful collisions ( when bonds are formed between reactants ).

Sarcoidosis has paradoxical effects on inflammatory processes ; it is characterized by increased macrophage and CD4 helper T-cell activation, resulting in accelerated inflammation, but immune response to antigen challenges such as tuberculin is suppressed.

Galvani and contemporaries regarded muscle activation as resulting from an electrical fluid or substance in the nerves.

Cytokines are humoral immunomodulatory proteins or glycoproteins which control or modulate the activities of target cells, resulting in gene activation, leading to mitotic division, growth and differentiation, migration, or apoptosis.

In both TSS ( caused by S. aureus ) and TSLS ( caused by S. pyogenes ), disease progression stems from a superantigen toxin that allows the nonspecific binding of MHC II with T cell receptors, resulting in polyclonal T cell activation.

Opening of NMDA channels ( which relates to the level of cellular depolarization ) leads to a rise in post-synaptic Ca < sup > 2 +</ sup > concentration and this has been linked to long term potentiation, LTP ( as well as to protein kinase activation ); strong depolarization of the post-synaptic cell completely displaces the magnesium ions that block NMDA ion channels and allows calcium ions to enter a cell – probably causing LTP, while weaker depolarization only partially displaces the Mg < sup > 2 +</ sup > ions, resulting in less Ca < sup > 2 +</ sup > entering the post-synaptic neuron and lower intracellular Ca < sup > 2 +</ sup > concentrations ( which activate protein phosphatases and induce long-term depression, LTD ).

Engagement of CD14 ( even at doses as minute as 10 pg / mL ) results in intracellular signaling via an associated " Toll-like receptor " protein 4 ( TLR-4 ), resulting in profound activation of mononuclear cells and production of potent effector cytokines such as IL-1 and TNF-α.

Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.

TrpB2i evolved into TrpB1, which formed permanent complexes with trpA resulting in bidirectional activation.

* Physical deformation of the particle ( e. g., stretching ) may increase the van der Waals forces more than stabilization forces ( such as electrostatic ), resulting coagulation of colloids at certain orientations.

A flat-plane full-coverage oral appliance, e. g. a non-repositioning stabilization splint, reduces bruxism in some patients, and can take stress off the temporomandibular joint, although some individuals may bite harder on it, resulting in a worsening of their conditions.

Thus, while most organic acids are deprotonated by the ionization of a polar hydrogen-to-oxygen bond, usually accompanied by some form of resonance stabilization ( resulting in a carboxylate ion ), uric acid is deprotonated at a nitrogen atom and uses a tautomeric keto / hydroxy group as an electron-withdrawing group to increase the pK < sub > 1 </ sub > value.

The recombination of the electron and hole, i. e. the decay of the exciton, is limited by resonance stabilization due to the overlap of the electron and hole wave functions, resulting in an extended lifetime for the exciton.

In contrast, positive feedback is feedback in which the system responds so as to increase the magnitude of any particular perturbation, resulting in amplification of the original signal instead of stabilization.

Specific mutations in p53 can disrupt these functions, allowing an abnormal cell to continue growing unchecked, resulting in the development of tumors.

The resulting sensitivity ( photophobia ) generally leads to discomfort in bright light, but this can be reduced by the use of sunglasses and / or brimmed hats.

* 1847 – After 17 months of travel, Brigham Young leads 148 Mormon pioneers into Salt Lake Valley, resulting in the establishment of Salt Lake City.

When the advertising method is shown to be a complete fraud, the resulting public reaction against the network leads to the chairman being removed, and Grossberg manages to assume the chairmanship.

This influence leads to political bargaining between the two remaining candidates and the parties and candidates who have been eliminated, sometimes resulting in the two successful candidates making policy concessions to the less successful ones.

Sexual conflict leads to an antagonistic co-evolution in which one sex tends to control the other, resulting in a tug of war.

It has been experimentally demonstrated that, as a consequence, when the magnetic field is increased beyond the critical field, the resulting phase transition leads to a decrease in the temperature of the superconducting material.

Sexual intercourse may be preceded by foreplay, which leads to sexual arousal of the partners, resulting in the erection of the penis or ( usually ) natural lubrication of the vagina.

Defective connective tissue also leads to fragile capillaries, resulting in abnormal bleeding.

* July 24 – After 17 months of travel, Brigham Young leads 148 Mormon pioneers into Salt Lake Valley, resulting in the establishment of Salt Lake City.

The resulting structure is believed to be a “ pre-pore ” since it is not electrically conductive but leads rapidly to the creation of a conductive pore.

Also, trade show models are articulate and quickly learn and explain or disseminate information on the company and its product and service, and can assist a company in handling a large number of attendees which the company might otherwise not have enough employees to accommodate, therefore increasing the number of sales or leads resulting from participation in the show.

The resulting NEFA flux to the liver causes impairment of liver metabolism which leads to over production of glucose in the liver.

This signaling cascade leads to PDGF receptor-dephosphorylation and a reduction in downstream signaling from this receptor, resulting in pericyte apoptosis …"

Selective pressures imposed on one another often leads to an evolutionary arms race between prey and predator, resulting in various antipredator adaptations.

Thus the resulting increase in permeability that leads to protein in the urine can explain the oedema if all other vessels are more permeable as well.

The resulting Battle of Sphacteria leads to a further victory by the Athenians over the Spartans.

The resulting Battle of Gaza leads to a triumph for Ptolemy and Seleucus over Antigonus ' son, Demetrius Poliorcetes (" sieger of cities "), who is captured but immediately released.

When Newt's decision to come forward as a witness leads to Booker's death, Marcus ambushes and confronts Newt with a gun – resulting in a vicious fight.

However, the resulting dissension among his family about the succession leads to a renewal of Carthaginian power in Sicily.

The resulting loss of elasticity in the lungs leads to prolonged times for exhalation, which occurs through passive recoil of the expanded lung.

This also leads to a reduction in anthropogenic CO2 generation ( resulting from removal of the sequestration afforded by woodlands and rainforests ).

After, Frank entices them to lose all inhibition and give in to their basest carnal instincts, resulting in everyone ’ s beginning to engage in orgiastic sex (" Don't Dream It – Be It ") before they are interrupted by Frank, who leads them into the concluding number of the floor show (" Wild and Untamed Thing ").

Ammonia arises from the impaired buffering of ADP, which leads to an increase in AMP concentration resulting in an increase in AMP deamination.