Thus, two drawbacks to elution mode chromatography, especially at the preparative scale, are operational complexity, due to gradient solvent pumping, and low throughput, due to low column loadings.

As a result, the growth was accompanied by growing pains: project failure was common, and the field of computer science was still in its early years, and the ambitions for project scale and complexity exceeded the market capability to deliver adequate products within a planned budget.

One point agreed on is that fractal patterns are characterized by fractal dimensions, but whereas these numbers quantify complexity ( i. e., changing detail with changing scale ), they neither uniquely describe nor specify details of how to construct particular fractal patterns.

" The ability to reduce everything to simple fundamental laws does not imply the ability to start from those laws and reconstruct the universe. The constructionist hypothesis breaks down when confronted with the twin difficulties of scale and complexity.

* Genetic algorithms do not scale well with complexity.

Clouds remain one of the largest uncertainties in future projections of climate change by global climate models, owing to the physical complexity of cloud processes and the small scale of individual clouds relative to the size of the model computational grid.

The idea's complexity and scale lured Brin to the job.

The PCAOB intends to issue further guidance to help companies scale their assessment based on company size and complexity during 2007.

* The complexity of the algorithm is rated at 25, using a relative scale where G. 711 is 1 and G. 729a is 15.

Jean Fouquet: The Martyrdom of St. Appolonia ( 1460 ), depicting the staging of a mystery play, led by a theatre directorIn Medieval times, the complexity of vernacular religious drama, with its large scale mystery plays that often included crowd scenes, processions and elaborate effects, gave the role of director ( or stage manager or pageant master ) considerable importance.

One result of this was that English castle sieges grew in complexity and scale.

" Connectance ( C ) is the fraction of all possible links that are realized ( L / S < sup > 2 </ sup >) and represents a standard measure of food web complexity ..." The distance ( d ) between every species pair in a web is averaged to compute the mean distance between all nodes in a web ( D ) and multiplied by the total number of links ( L ) to obtain link-density ( LD ), which is influenced by scale dependent variables such as species richness.

The music of overtures is to inspire listeners to imagine scenes, images, or moods ; Liszt intended to combine those programmatic qualities with a scale and musical complexity normally reserved for the opening movement of classical symphonies.

Thus, two drawbacks to elution mode chromatography, especially at the preparative scale, are operational complexity, due to gradient solvent pumping, and low throughput, due to low column loadings.

As the scale and complexity of refugee issues continued to increase, the UNHCR and the international community at large was better positioned to adapt.

OS / 8 provided a simple operating environment that was commensurate in complexity and scale with the PDP-8 computers on which it ran.

The artistic presentations have grown in scale and complexity as successive hosts attempt to provide a ceremony that outlasts its predecessor's in terms of memorability.

A fractal dimension is a ratio providing a statistical index of complexity comparing how detail in a pattern ( strictly speaking, a fractal pattern ) changes with the scale at which it is measured.

The matrix cell in row " accuracy of measurement " and column " complexity of control " points to several principles, among them the Copying Principle, which states, " Use a simple and inexpensive optical copy with a suitable scale instead of an object that is complex, expensive, fragile or inconvenient to operate.

Also, the computational complexity of computer simulation of the real world increases even more rapidly when the scale gets more precise.

The paintings in the Vatican by Michelangelo and Raphael are said by some scholars such as Stephen Freedberg to represent the culmination of High Renaissance style in painting, because of the ambitious scale of these works, coupled with the complexity of their composition, closely observed human figures, and pointed iconographic and decorative references to classical antiquity, can be viewed as emblematic of the High Renaissance.

Such instruments provide nanometer scale imaging, analysis and fabrication capabilities at the expense of system complexity.

In order to reduce the administrative complexity, a new non-departmental trust fund called the National Employment Savings Trust is established as a cheaper public competitor, able to take advantage of significant economies of scale, compared to existing fund manager options on the private pension market.

Nettl describes Pueblo music, including Hopi, Zuni, Taos Pueblo, San Ildefonso Pueblo, Santo Domingo Pueblo, and many others, as one of the most complex on the continent, featuring increased length and number of scale tones ( hexatonic and heptatonic common ), variety of form, melodic contour, and percussive accompaniment, ranges between an octave and a twelfth, with rhythmic complexity equal to the Plains sub-area.

Kobayashi wrote, “ Kitagawa Utamaro was an outstanding figure in the world of popular art and literature, but that world itself was at the bottom of the social scale.

The Binet-Simon scale was and is hugely popular around the world, mainly because of the vast literature it has fostered, as well as its relative ease of administration.

The speeches of the condemned, biographies of criminals, and trial literature, were popular genres during the late 17th and early 18th centuries ; written for a mass audience and a precursor to the modern novel, they were " produced on a scale which beggars comparison with any period before or since ".

* 2008 PEN / Saul Bellow Award for Achievement in American Fiction, for a career whose writing " possesses qualities of excellence, ambition, and scale of achievement over a sustained career which place him or her in the highest rank of American literature.

The scale and nature of the benefits of CSR for an organization can vary depending on the nature of the enterprise, and are difficult to quantify, though there is a large body of literature exhorting business to adopt measures beyond financial ones ( e. g., Deming's Fourteen Points, balanced scorecards ).

The term " succession planting " usually appears in literature for home gardening and small-scale farming, although the techniques apply to any scale.

Upon publication, Angle of Repose was praised nearly unanimously by critics for being both "... the most ambitious and deeply realized of works " and on a larger scale, "... a major piece of literature ".

In the founder's own words, the literary pursuit of the fraternity must " be built on a more comprehensive scale than other societies, ... providing for every variety of taste and talent and embracing every department of literature and science ...

A large scale project has been recording traditional narrations and writing them down to provide the literate Ticunas with some literature to practice with.

Instead of dealing with heroes from classical literature or the Bible, presented with spectacle and grand stage effects, his subjects concerned everyday people, such as his audience, the theater-going middle classes, and his tragedies were conducted on the intimate scale of households, rather than kingdoms.

Fantasy literature reviewer Patrick on his blog Pat's Fantasy Hotlist gave the novel a very positive review and a score of 9 / 10, calling it " the beginning of something truly special ", and concluding " Imaginative on a scale that's almost frightening to consider, absorbing, thoroughly complex -- that's Gardens of the Moon in a nutshell.

Smaller scale subjects from literature were also popular, pioneered by Francis Hayman, one of the first to paint scenes from Shakespeare, and Joseph Highmore, with a series illustrating the novel Pamela.

In 2011 a large scale review of the literature on mirror therapy by Rothgangel summarized the current research as follows:

In 2011 a large scale review of the literature on mirror therapy by Rothgangel ( Rothgangel et al., 2011 ) summarized the current research as follows.

Because of its succinct presentation of the theory, Raglan's scale is still frequently used as a teaching tool in cultural anthropology and comparative literature.

Karşıyaka is deeply associated with commerce, construction of residences, education and literature, and is a prized area for pensioners, not only in the scale of İzmir but also from across Turkey as a whole.

Whereas Damrosch ’ s approach remains tied to the close reading of individual works, a very different view was taken by the Stanford critic Franco Moretti in a pair of articles offering “ Conjectures on World Literature .” Moretti argued that the scale of world literature far exceeds what can be grasped by traditional methods of close reading, and he advocated instead a mode of “ distant reading ” that would look at large-scale patterns as discerned from publication records and national literary histories, enabling one to trace the global sweep of forms such as the novel or film.