The binding of nuclear receptors by glucocorticoids, heat, radiation, nutrient deprivation, viral infection, hypoxia and increased intracellular calcium concentration, for example, by damage to the membrane, can all trigger the release of intracellular apoptotic signals by a damaged cell.

Conversely, the withdrawal syndrome may also be a trigger for relapse.

Recent research by the Imperial College London has focused on finding new cell wall proteins which trigger an immune response and are suitable for use in a vaccine to provide long-term protection against M. tuberculosis.

Some developed a gangster-like slang for the verb to kill in an attempt to distance themselves from the killings, such as ' shooting partridges ', of ' sealing ' a victim, or giving him a natsokal ( onomatopoeia of the trigger action ).

This nut has a perpendicular center slot for the bolt, and an intersecting axial slot for the string, along with a lower face or slot against which the internal trigger sits.

The bronze triggers were designed in such a way that they were able to store a large amount of energy within the bow when drawn, but was easily fired with little recoil when the trigger were pulled ( this allowed it for precision shooting ).

* Cascading failure, a failure in a system of interconnected parts, for example a power transmission grid, where the service provided depends on the operation of a preceding part, and the failure of a preceding part can trigger the failure of successive parts.

Double trigger designs are typically set up for right-handed users.

Dicing is mentioned as an Indian game in the Rigveda, Atharvaveda and Buddha games list ; it also plays a critical role in the great Hindu epic Mahabharata, where Yudhisthira plays a game of dice against the Kauravas for the northern kingdom of Hastinapura, which becomes the trigger for a war.

His first action is to trigger a nuclear weapon in orbit around the Earth, in order to absorb the energy contained within for his own use.

Sometimes, for the sake of appearance or of the desired " feel " of the instrument, a drum with a trigger will be used as a trigger pad by muffling it so heavily that no significant sound at all is produced, see Electronic drum # Acoustic triggered drum kit.

However, after increasing demand of salary in their arbitration years and uncertainty of stadium situation, the Marlins pulled the trigger on dealing slugger Miguel Cabrera and southpaw Dontrelle Willis to the Detroit Tigers for outfielder Cameron Maybin, southpaw Andrew Miller, reliever Burke Badenhop among the six players received by Florida.

A handler's finger may involuntarily move for any of several reasons: the handler is startled, a lack of full attention on body movements, physiological reasons beyond conscious control such as a spasm, stumbling or falling, or the finger being pushed by something ( as when trying to holster a handgun with one's finger on the trigger ).

The trigger guard and area above the trigger of a firearm presents a natural point for a handler to keep their finger out straight alongside the weapon, so as not to violate this rule.

: Although there are no universal standards for the design or testing of trigger locks, some jurisdictions, such as the state of California, maintain a list of approved trigger lock devices.

According to another view, Valerian's disaster and capture at the battle of Edessa was the trigger for the subsequent revolts of Ingenuus, Regalianus and Postumus.

Penalty throws should only trigger a timeout for lengthy delays as a change of the goalkeeper.

The immediate trigger for the Revolution was Louis XVI's attempts to solve the government's worsening financial situation.

Such cells, tissues and organs would neither trigger an immune response nor require the use of Immunosuppressive drugs Both basic research and therapeutic development for serious diseases such as cancer, heart disease and diabetes, as well as improvements in burn treatment and reconstructive and cosmetic surgery, are areas that might benefit from such new technology.

As Harvard hypnotherapist Deirdre Barrett describes in the book “ Tales from a Hypnotherapist ’ s Couch ”, most modern research suggestions are designed to bring about immediate responses — an arm rises immediately, whereas hypnotheraputic suggestions are usually post-hypnotic ones that are intended to trigger responses affecting behavior for periods ranging from days to a lifetime in duration.

Plate anemometers have been used to trigger high wind alarms on bridges. They are used on these high places because they are in a plate shape ; has a good measurement status on higher altitudes.

One system employed in these devices was the use of pegs and cams placed into a wooden drum at specific locations, which would sequentially trigger levers that in turn operated percussion instruments.

To trigger these sounds in real-time, Lee uses MIDI controllers, placed at the locations on the stage where he has a microphone stand.

According to these theories, neither nature nor nurture alone is sufficient to trigger language learning ; both of these influences must work together in order to allow children to acquire a language.

The task for the seller is to identify these price points and to reduce the price once one is reached in the hope that a reduced price will trigger additional purchases from the consumer.

In their view, minds structure certain communicable aspects of the ideas produced, and these communicable aspects generally trigger or elicit ideas in other minds through inference ( to relatively rich structures generated from often low-fidelity input ) and not high-fidelity replication or imitation.

A portion of these neutrons may later be absorbed by other fissile atoms and trigger further fission events, which release more neutrons, and so on.

In order to prevent inappropriate or premature activation of the digestive enzymes ( they may, for example, trigger pancreatic self-digestion ), these enzymes are secreted as inactive zymogen.

To overcome these shortcomings, the 16550 series UARTs incorporated a 16-byte FIFO with a programmable interrupt trigger of 1, 4, 8, or 14 bytes.

Worse, when these enzymes are released from the non-dead cell, they can trigger a chain reaction of further cell death.

The several benefits of these include the ability to view analog and digital signals together in time, and to trigger on either digital or analog signals and capture on the other.

The technology behind these methods have evolved, from panels at the fire department ( which could trigger and control green lights for certain major corridors ) to optical systems ( which the individual fire apparatus can be equipped with to communicate directly with receivers on the signal head ).

When the clear tape reaches one of these, enough light will pass through the tape to the photodiode to trigger the stop function ; in more sophisticated machines it will start rewinding the cassette when the trailing end is detected.

Which actions short of official recognition and full diplomatic relations would trigger sanctions, and what these sanctions would be, was deliberately kept unclear — at least publicly — in order to prevent foreign governments testing the limits.

Disillusionment rising from the establishment is a cause widely used in separatist movements, but it is usually severe economic difficulties that trigger these groups into action.

The Emperor unified China at least in part by equipping large armies with these weapons, which were equipped with a sophisticated trigger mechanism made of interchangeable parts.

There are several changes that may occur in an infectious agent that may trigger an epidemic these include:

Notwithstanding these concerns, Hersh reported that " INC supporters in and around the Administration, including Paul Wolfowitz and Richard Perle, believe, like Chalabi, that any show of force would immediately trigger a revolt against Saddam within Iraq, and that it would quickly expand.

When Nikki Wood's son Robin tries to kill Spike, he unwittingly frees Spike from his hypnotic trigger: the song " Early One Morning ", a favorite of his mother, which evokes Spike's traumatic memories of his mother's abusive behavior toward him after she turned ; after Spike is able to address these issues, he realizes his mother had always loved him, knowledge which frees him from the First's control.

Along with ' some sound in the traffic or the smell of horse dung or something ' these thoughts trigger Bowling's memory of his childhood as the son of an unambitious seed merchant in " Lower Binfield " near the River Thames.

Given the great depth of Lake Tahoe, and the locations of the normal faults within the deepest portions of the lake, modeling suggests that earthquakes on these faults can trigger tsunamis.

The first attempt was by aircraft bombs attached to lanyards which would trigger their charges ; a similar idea was a guncotton charge in a lanyarded can ; two of these lashed together became known as the Depth Charge Type A.

TfL has stated it is keeping a database of these numbers and that they will trigger an alert.