In the last few years, the application of chromatographic and other modern techniques to the problem of isolating TSH has led to further purification ( Bates and Condliffe, 1960 ; ;

This refusal to accept any renunciation of allegiance to the Crown led to conflict with the United States over impressment, and then led to further conflicts even during the War of 1812, when thirteen Irish American prisoners of war were executed as traitors after the Battle of Queenston Heights ; Winfield Scott urged American reprisal, but none was carried out.

This led to a further revolt near Philippopolis, and the commander of the field army in the west, Gregory Pakourianos, was defeated and killed in the ensuing battle.

Pericles led 250 ships, originally intended to attack Cyprus, to their aid because it would further damage Persia.

Such a thin chronology and little background knowledge has led to gross misinterpretations of his works, and thus further investigation must always be done to conclude with confidence that Aelbert Cuyp is the genuine source of such great paintings.

The lack of artifacts caused concern for some archaeologists and the petrofabric analysis was inconclusive, but further research at Maes Howe and on the Bush Barrow Lozenge led MacKie to conclude that while the term ' science ' may be anachronistic, Thom was broadly correct upon the subject of high-accuracy alignments.

The discovery of chlorpromazine's psychoactive effects in 1952 led to greatly reduced use of restraint, seclusion, and sedation in the management of agitated patients, and also led to further research that resulted in the development of antidepressants, anxiolytics, and the majority of other drugs now used in the management of psychiatric conditions.

As an ethologist, Morris further proposed that breasts, a secondary sex characteristic located on the woman's chest, encouraged face-to-face sexual intercourse that led to the establishment of an emotional bond between man and woman ; social progress from an essentially procreational function of human biology.

The success of this paper led to five further publications, The Rover and The Wizard in 1922, The Vanguard in 1924, The Skipper in 1930 and The Hotspur in 1933.

A railway station on Brighton Road ( on the Birmingham to Bristol line ) led to further expansion, and the end of the 19th century saw a proliferation of high-density small terraced houses.

Further improvement upon the idea of instruction pipelining led to the development of a method that decreases the idle time of CPU components even further.

It led to the system of Constitutional Monarchy, with further reforms shifting the balance of power from the monarchy and nobility to the House of Commons.

This led to further resentment and suggestions that these same freedmen were ruling the Emperor.

This, arguably has led to uneven development, and further informal forms of social control having to do with culture and imperialism.

The subsequent Treaty of Versailles led to further territorial and financial losses.

The ancient Amber Road led further southwest and southeast to the Black Sea and eventually to Asia.

This was further underpinned by the work of Justus von Liebig, which led to the development of modern food storage and food preservation methods.

From 1900, the Pathé company films also frequently copied and varied the ideas of the British film-makers, without making any major innovations in narrative film construction, but eventually the sheer volume of their production led to their film-makers giving a further precision and polish to the details of film continuity.

" This sentence is located randomly in the middle of a discussion of southern Italy ; no further mention of Britain is made, which has led some, though not all, modern academics to suggest that the rescript does not apply to Britain, but to Bruttium in Italy.

The various Divisions are further divided into sub Branches, led by Deputy Assisant Directors.

In June 2009, the European Court of Auditors published a report, pointing out governance issues, substantial delays and budget overruns that led to project stalling in 2007, leading to further delays and failures.

It was replaced by a second version one month later, followed by six further drafts published by IETF itself that finally led to HTML 2. 0 in RFC1866

Other writers acknowledge his extremely high popularity at home, but suppose his occasionally rigid and even irrational political loyalties and convictions contributed greatly to Spartan decline, notably his unremitting hatred of Thebes, which led to Sparta's humiliation at the Battle of Leuctra and thus the end of Spartan hegemony.

Warfare between city states had led to a population decline, from which Akkad provided a temporary respite.

The rise of computer use is one of the reasons said to have led to a relative decline in board games.

The islands prospered economically until the middle of the Nineteenth Century, when a combination of the abolition of slavery in the Territory, a series of disastrous hurricanes, and the growth in the sugar beet crop in Europe and the United States significantly reduced sugar cane production and led to a period of economic decline.

Prior to this time, Judah had been a vassal of the Assyrian empire, but the rapid decline of Assyria after c. 630 led Josiah to assert his independence and institute a religious reform stressing loyalty to Yahweh, the national God.

A recent report ( 2006 ) by the NOAA's Southwest Fisheries Science Center in La Jolla, California, indicates that the increased rat presence on Clipperton Island has led to a decline in both crab and bird populations, causing a corresponding increase in both vegetation and coconut palms on the island.

It was this same bureaucracy that later prevented the Ming government from being able to adapt to changes in society, and eventually led to its decline.

This combination of events, coupled with an ongoing decline in British military and economic support to the region as the Home Office favoured newer colonial endeavours in Africa and elsewhere, led to a call among Maritime politicians for a conference on Maritime Union, to be held in early September 1864 in Charlottetown-chosen in part because of Prince Edward Island's reluctance to give up its jurisdictional sovereignty in favour of uniting with New Brunswick and Nova Scotia into a single colony.

The traditional staples thesis, advocated by scholars such as S. A. Saunders, looks at the resource endowments of the Maritimes and argues that it was the decline of the traditional industries of shipbuilding and fishing that led to Maritime poverty, since these processes were rooted in geography, and thus all but inevitable.

Factors that have been cited as leading to the decline of disco in the United States include economic and political changes at the end of the 1970s as well as burnout from the hedonistic lifestyles led by participants.

This led Kraepelin to name what we now know as schizophrenia, dementia praecox ( the dementia part signifying the irreversible mental decline ).

Soga no Umako, who succeeded his father as Ōomi of the Soga clan, eventually killed Mononobe no Moriya at the Battle of Shigisan, the head of the Mononobe clan, which led to its decline.

In Denmark the Nordisk company increased its production so much in 1915 and 1916 that it could not sell all its films, which led to a very sharp decline in Danish production, and the end of Denmark's importance on the world film scene.

Decline in food production, growth of the population, and competition for resources among the great families all led to the gradual decline of Fujiwara power and gave rise to military disturbances in the mid-tenth and eleventh centuries.

This event marked the beginning of the browser's popularity decline, which led to its discontinuation in September 2008.

At the same time the rising popularity of Firefox, its status of the default browser in major distribution and the overwhelming number of its extensions led to decline of Galeon's user base.

Ratings decline led to most of the prime time games being canceled.

Spain's European wars led to economic damage, and the latter part of the 17th century saw a gradual decline of power under an increasingly neglectful and inept Habsburg regime.

However economic decline and conflict between the Druze and the Ottomans led to the community's gradual decline by the mid-17th century.

Dissatisfaction with Company rule led to the Indian Rebellion of 1857, after which the British provinces of India were directly administered by the British Crown and witnessed a period of both rapid development of infrastructure and economic decline.

Recent decline in population size of the Ozark subspecies Cryptobranchus alleganiensis bishopi has led to further research into populations of this subspecies, including genetic analysis to determine the best route for conservation status.

This led to the devaluation of national currencies and a decline in world trade.

Although Marx won this contest, the transfer of the seat of the General Council from London to New York in 1872, which Marx supported, led to the decline of the International.