Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors.

Thus, it might be used to challenge the sharp distinction made in U. S. v. E. C. Knight ( 1895 ) between commerce, which was subject to federal regulation, and manufacturing, which was not.

Thus, knowledge about cultural norms is important for impressions, which is an individual's regulation of their nonverbal behavior.

Thus, the bacterium can cause a chronic active gastritis ( type B gastritis ), resulting in a defect in the regulation of gastrin production by that part of the stomach, and gastrin secretion can either be increased, or as in most cases, decreased, resulting in hypo-or achlorhydria.

Thus, in a governmental context, " planning " without any qualification is most likely to mean the regulation of land use.

Thus, a regulation that allows member states to privatise roads would not have direct effect and could not be enforced in the courts, because it provides that states may privatise roads, not must privatise roads.

Thus, a HVAC control system applies regulation to e. g. a heating.

Thus an increase in the temperature in the material undergoing fusion does not act to expand the material and by doing so cool, and there is no regulation of the rate of fusion.

Thus, any activating mutation downstream of SOS1 may be subject to less regulation that may mitigate the consequence of such mutations giving rise to the phenotypic differences seen between these syndromes.

Thus, Wee1 localizes with its inhibitory network, which demonstrates that mitosis is controlled through Cdr2-dependent negative regulation of Wee1 at the medial cortical nodes.

Thus, a novel mechanism for regulation of gene expression, the epigenetic silencing of genes by miRNAs, was discovered.

" Thus, in proving that a framework convention was needed for tobacco control, treaty advocates invoked tobacco-related issues that could not be resolved by the actions of individual countries, such as the smuggling of tobacco and the leakage of tobacco advertisements from countries which lacked stringent regulation to those with restrictions on where and to whom tobacco companies could market their products.

Thus, the surety on a bond is usually an insurance company whose solvency is verified by private audit, governmental regulation, or both.

Thus, it appears RYGB affects weight loss by altering the physiology of weight regulation and eating behavior rather than by simple mechanical restriction or malabsorption.

Thus the systemic risk migrated from one sector to another and proves that regulation of only one industry cannot be the sole protection against systemic risks.

Thus, while transcriptional regulation generates rhythmic RNA levels, regulated posttranslational modifications control protein abundance, subcellular localization, and repressor activity of PER and CRY.

Thus, as well as the PEP group translocation system being an efficient way to import substrates into the bacterium, it also links this transport to regulation of other relevant proteins.

Thus blood glucose levels play an important role in regulation of proIAPP synthesis.

Thus, an outdoors utility knife suited for camping or hunting might use a broad three to five-inch fixed blade, while a utility knife designed for the construction industry might feature a replaceable utility or razor blade for cutting packaging, cutting shingles, marking cut lines, or scraping paint.

Thus filters designed in the continuous-time domain that are stable are converted to filters in the discrete-time domain that preserve that stability.

Thus, many typical household applications already in existence like word processing and email were designed specifically to avoid using floating point operations.

Thus far, no key escrow system has been designed which meets both objections and nearly all have failed to meet even one.

Thus began one of the most famous apprenticeships in the musical theatre, as Hammerstein designed a kind of course for Sondheim on the construction of a musical.

Thus, it is possible to build the overall layout of a product before the parts are designed.

Thus, a battery designed to operate for at ( 77 ° F ) approximately would last only at ( 92 ° F ), and would last only at ( 107 ° F ).

Thus, a battery designed to operate for at ( 77 ° F ) would last at ( 113 ° F ).

Thus they may be more clearly designed for the entertainment of readers.

Thus, engines designed to run high-octane fuel exclusively can achieve higher compression ratios.

Thus most game designs through the 1980s were designed through a hard-coded ruleset with a small amount of level and graphics data.

Thus, the Benedictbeurn Passion Play ( thirteenth century ) is still largely composed of Latin ritual sentences in prose and of church hymns, and, being designed to be sung, resembles an oratorio.

Thus, without having a separate brand from the now defunct company, Chrysler looked to re-brand the legacy vehicles inherited through the purchase of AMC instead of trying to fold those outside designed products into Chrysler's existing branch structure.

Thus, in 1649, when Louis XIV was still a child, an artisan named Camus designed for him a miniature coach, and horses complete with footmen, page and a lady within the coach ; all these figures exhibited a perfect movement.

Thus, the Governor Palace was designed by Italians, City Hall by Germans, etc.

Thus, many cryptosystems and security systems are designed with special emphasis on keeping human vulnerability to a minimum.

Thus, the contracts must be designed to ensure that each side is capable of performing the obligations set out.

Thus, there are hair salons that have well designed waiting areas often with magazines and plush sofas for patrons to read and relax while they await their turn.

Thus Interactive TV applications are often designed for the " 10-foot user interface " while PC applications and web pages are designed for the " 3ft user experience ".

Thus CA is neither designed for, nor aimed at, examining the production of interaction from a perspective that is external to the participants ' own reasoning and understanding about their circumstances and communication.

Thus, the more developed market economies agreed with the U. S. vision of post-war international economic management, which was to be designed to create and maintain an effective international monetary system and foster the reduction of barriers to trade and capital flows.

Thus the lower stage motors are designed for use at atmospheric pressure, while the upper stages can use motors suited to near vacuum conditions.

Thus a defensive building might be designed and built with battlements, or a manor house might be fortified by adding battlements, where no parapet previously existed, or cutting crenellations into its existing parapet wall.