When an APAF-1 gene trap is introduced into cells, many morphological changes occur, such as spina bifida, the persistence of interdigital webs, and open brain.

When the body is healthy the brain is healthy and less inflamed as well.

Le Laboratoire des Hallucinations, by André de Lorde: When a doctor finds his wife's lover in his operating room, he performs a graphic brain surgery rendering the adulterer a hallucinating semi-zombie.

There he repeated in a different form all that he had already said, for all the world as if he had a gramophone fixed in his brain ... When I took leave, he subjected me to an interminable handshake, meanwhile fixing his cold blue eyes on mine, and repeating almost word for word what he said to me on arrival ... I felt I should never be able to establish any human contact with this man " In early June 1940, when Mussolini informed Hitler that he at long last would enter the war on 10 June 1940, Hitler was most dismissive, in private calling Mussolini a cowardly opportunist who broke the terms of the Pact of Steel in September 1939 when the going looked rough, and was only entering the war in June 1940 after it was clear that France was beaten and it appeared that Britain would soon make peace.

When Phe cannot be metabolized by the body, abnormally high levels accumulate in the blood and are toxic to the brain.

When left untreated, complications of PKU include severe mental retardation, brain function abnormalities, microcephaly, mood disorders, irregular motor functioning, and behavioral problems such as attention deficit hyperactivity disorder.

When the blood – brain barrier regains its integrity, typically after the infection or virus has cleared, the T cells are trapped inside the brain.

When Beaumont was 34 and overwhelmed by numerous writing commitments, he began to suffer the effects of what has been called " a mysterious brain disease ".

When hexosaminidase A is no longer functioning properly, the lipids accumulate in the brain and interfere with normal biological processes.

When these irritate the brain, the person develops hepatic encephalopathy ( confusion, coma, seizures and finally life-threatening swelling of the brain ).

When diagnostic tests confirm his suspicions, Judith agrees to surgery to remove a malignant brain tumor.

When feeling motion but not seeing it ( for example, in a ship with no windows ), the inner ear transmits to the brain that it senses motion, but the eyes tell the brain that everything is still.

When the brain is led to believe that the saccades it is generating are too large or too small ( by an experimental manipulation in which a saccade-target steps backwards or forwards contingent on the eye movement made to acquire it ), saccade amplitude gradually decreases ( or increases ), an adaptation ( also termed gain adaptation ) widely seen as a simple form of motor learning, possibly driven by an effort to correct visual error.

When the meninges are inflamed, the blood – brain barrier may be disrupted.

When an organism experiences a reinforcing stimulus, dopamine pathways in the brain are activated.

When people feel stressed, stress hormones get over-secreted, which affects the brain.

When a digital image is viewed, a reconstruction is performed by a display or printer device, and by the eyes and the brain.

When Bmi1 was knocked out in mice, impaired cerebellar development resulted, leading to significant reductions in postnatal brain mass along with abnormalities in motor control and behavior.

When a person decides to walk across a room, it is generally understood that the decision to do so, a mental event, immediately causes a group of neurons in that person's brain to fire, a physical event, which ultimately results in his walking across the room.

When we are planning for the future and thinking about possible actions to take in the future, we are utilizing considerable amounts of biologically expensive resources ( brain power ).

When the sounds from two speakers mix, they create the phase difference the brain uses to locate direction.

When a flea bites a human and contaminates the wound with regurgitated blood, the plague carrying bacteria are passed into the tissue.

When the rate of bone formation exceeds the rate of bone resorption, soft tissue < sup > 44 </ sup > Ca /< sup > 40 </ sup > Ca rises.

When attacking smaller prey, such as young lambs, the kill is made by biting the skull and spinal regions, causing massive tissue and bone damage.

When a particular substance, whether chemical or biotic — reaches unsafe levels in the bloodstream, the body can effectively dilute — or at least maintain equilibrium of — the offending substances by storing it in new fat tissue.

When actress Louise Brooks met Bogart in 1924, he had some scarred tissue on his upper lip, which Belmont Bogart may have partially repaired before Bogart went into films in 1930.

When the electricity applied to the tissue is above the electric field threshold of the target tissue, the cells become permanently permeable from the formation of nanopores.

When used as scaffolds, hydrogels may contain human cells to repair tissue.

When lists are generated many factors are taken into consideration ; these factors include: distance of transplant center from the donor hospital, blood type, medical urgency, wait time, donor size and tissue typing.

When this is not available ( e. g. because a court order may be needed and not obtainable ) other methods may need to be used to collect a sample of blood, saliva, semen, or other appropriate fluid or tissue from personal items ( e. g. toothbrush, razor, etc.

* By body part: When surgery is performed on one organ system or structure, it may be classed by the organ, organ system or tissue involved.

When dissected, the arrangement of the cells in a root is root hair, epidermis, epiblem, cortex, endodermis, pericycle and lastly the vascular tissue in the centre of a root to transport the water absorbed by the root to other places of the plant.

When the amount of copper in the liver overwhelms the proteins that normally bind it, it causes oxidative damage through a process known as Fenton chemistry ; this damage eventually leads to chronic active hepatitis, fibrosis ( deposition of connective tissue ) and cirrhosis.

When administered via a central lumen catheter, adenosine has been shown to initiate atrial fibrillation because of its effect on atrial tissue.

When stretched, tendons have a soft tissue mechanical behavior.

When the labial tissue heals, it forms a wall of skin and flesh across the vagina and the rest of the pubic area.

When a monocyte enters damaged tissue through the endothelium of a blood vessel, a process known as the leukocyte extravasation, it undergoes a series of changes to become a macrophage.

When a thrombus occupies more than 75 % of cross-sectional area of the lumen of an artery, blood flow to the tissue supplied is reduced enough to cause symptoms because of decreased oxygen ( hypoxia ) and accumulation of metabolic products like lactic acid.

When chronic, they can form cyst-like enlargements of the connective tissue around the sheaths of muscle tendons, becoming very painful when moved.

When the endothelial layer is injured, collagen, vWF and tissue factor from the subendothelium is exposed to the bloodstream.

When he returns alone ( His companion having been killed during the hunt ), badly wounded, and with a chunk of burnt tissue he claims is from the monster, he is drugged and restrained.

When a cholesteatoma or granulation tissue is present in the middle ear, the degree of hearing loss and ossicular destruction is even greater.

When available at all, cesarean sections and other medical interventions are usually not performed until after tissue damage has already been done.

According to Touliopolous, CECC of the leg is a condition caused by exercise which results in increase tissue pressure within a limited fibro-osseous compartment-muscle size may increase by up to 20 % during exercise ( Touliopolous, 1999 ) When this happens pressure builds up in the tissues and muscles causing tissue ischemia ( Touliopolous, 1999 ).