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# and Saxony
# Count Bernhard of Anhalt ( 1140 – 9 February 1212 ), Duke of Saxony from 1180-1212 as Bernard III
# REDIRECT Albert III, Duke of Saxony
# REDIRECT Frederick Augustus I of Saxony
# Johann ( b. Dresden, 24 August 1498 – d. Dresden, 11 January 1537 ), Hereditary Duke of Saxony ; married on 20 May 1516 to Elizabeth of Hesse.
# Frederick ( b. Dresden, 15 March 1504 – d. Dresden, 26 February 1539 ), Hereditary Duke of Saxony ; married on 27 January 1539 to Elisabeth of Mansfeld.
# Otto I ( 912 – 973 )-Duke of Saxony, King of Germany, and Holy Roman Emperor
# Sophie ( 6 June 1568 – 7 December 1622 ), married in 1582 to Elector Christian I of Saxony
# Otto ( 912 – 973 ), Duke of Saxony, King of Germany and Holy Roman Emperor
# REDIRECT Saxony
# The Quadruple Alliance of 1745 was formed between the United Kingdom, the Dutch Republic, Saxony and Austria in the later stages of the War of the Austrian Succession.
# Frederick Augustus I of Saxony ( 23 December 1750-5 May 1827 ) married Amalie of Zweibrücken-Birkenfeld had issue.
# Anton of Saxony ( 27 December 1755-6 June 1836 ) married Maria Carolina of Savoy no issue ; married Maria Theresa of Austria no surviving issue.
# Maria Amalia of Saxony ( 26 September 1757-20 April 1831 ) married Karl II August of Zweibrücken and had issue.
# Maximilian of Saxony ( 13 April 1759-3 January 1838 ) married Princess Caroline of Parma and had issue ; married secondly Maria Luisa of Bourbon-Parma without issue.
# Frederick I, Elector of Saxony, 1370 – 1428
# Frederick II, Elector of Saxony, 1412 – 1464
# Ernest, Elector of Saxony, 1441 – 1486
# John, Elector of Saxony, 1468 – 1532
# John Frederick I, Elector of Saxony, 1503 – 1554
# Maria Carolina of Savoy ( 17 January 1764 – 28 December 1782 ) married Antony, Electoral Prince of Saxony in 1781, no issue.
# Prince Ferdinand of Savoy ( 1822 – 55 ), Duke of Genoa married Princess Elisabeth of Saxony
# East Frisia or Eastern Friesland ( German Ostfriesland ; East Frisian Low Saxon: Oostfreesland ) in Lower Saxony
# REDIRECT List of rulers of Saxony
# REDIRECT List of rulers of Saxony
# Saxony

# and antagonist
* Eddie Martel # 7 ( Brett Cullen ) — Regular first-string quarterback for the Washington Sentinels, two-time Super Bowl winner, and primary antagonist.
Appearing for the first time in The Amazing Spider-Man # 129 ( Feb. 1974 ), the Punisher was initially an antagonist of the titular hero.
# REDIRECT H2 antagonist
# REDIRECT H2 antagonist
# REDIRECT H2 antagonist
The character initially appears as an antagonist to the X-Men, although before long he becomes a member of the Avengers and appears as a regular character in that title beginning with Avengers # 16 in May 1965.
# REDIRECT Histamine antagonist
Broome and artist Irwin Hasen created the supervillian Per Degaton as a JSA antagonist in All-Star Comics # 35 ( July 1947 ).
The character initially appeared as an antagonist of the New Mutants and X-Men, but eventually joined the New Mutants in issue # 99 of that series, and the team became known as X-Force in the first issue of that series.
The game contains many features that would later become a staple of the Xiao Xiao series, including revamped animation and character design, most notable the introduction of the series ' main antagonist, " The Boss " ( although he is not referred to by name until Xiao Xiao # 3 ), a magenta-colored crime boss who acts as the final challenge of the game via a boss fight.
# REDIRECT Histamine antagonist
Nocenti introduced the popular antagonist Typhoid Mary in issue # 254 ( May 1988 ).
* " Muscles " McGinnis-The antagonist of a story included in Captain Marvel Adventures # 3 ( 1941 ), the toughest gangster of the city possessing enormous strength " Muscles " McGinnis promises to go straight after being defeated by Captain Marvel when he tries to take over Whiz Radio Station, as he feels the side opposing crime is much stronger.
# REDIRECT Histamine antagonist
An alternate version of Parasite appeared in DC Comics ' All-Star Superman # 5 as an antagonist in the main subplot.
# REDIRECT Interleukin 1 receptor antagonist
# History of GnRH agonist and antagonist development
# REDIRECT Gonadotropin-releasing hormone antagonist
# Competitive antagonist — a molecule that binds to the same site on the receptor protein as the agonist, preventing activation of the receptor
# Non-competitive antagonist — a molecule that binds to a receptor protein on a different site than that of the agonist, but causes a conformational change in the protein that does not allow activation.
Created by writer Roy Thomas and penciler Gil Kane, the character, a living human suffering from vampiric abilities resulting from scientific rather than supernatural means, first appeared as an antagonist in The Amazing Spider-Man # 101 ( Oct. 1971 ), and went on to become a heroic, tragically flawed protagonist in his own series and other titles.
A tragic and sympathetic antagonist in his initial two-issue arc, having acquired his vampiric addiction while researching a cure for his own rare, fatal blood disease, Morbius collided again with Spider-Man and others in Marvel Team-Up # 3-4 ( July & Sept. 1972 ).
During this period, Morbius again appeared as an antagonist in the Spider-Man one-shot, Giant-Size Super-Heroes # 1 ( June 1974 )
# REDIRECT Dopamine antagonist

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