With advances in medicinal chemistry, most of today's antibacterials chemically are semisynthetic modifications of various natural compounds.

With no effective long-range weapon the original Blue Steel served on after a crash programme of minor modifications to permit a low-level launch at, even though its usefulness in a hot war was likely limited.

With certain modifications, the most important of which were introduced later by Aasen himself, but also through a latter policy aiming to merge this Norwegian language with Dano-Norwegian, this language has become Nynorsk (" New Norwegian "), the second of Norway's two official languages ( the other being Bokmål, the Dano-Norwegian descendant of the Danish language used in Norway at Aasen's time ).

With only minor modifications, it is used in Inner Mongolia to this day.

A press release stated, " With slight modifications, such as no pork-based products, and the use of soy-based cheese product, the menu is virtually identical to that of any other Subway restaurant.

With relatively small modifications, the Liber Augustalis remained the basis of Sicilian law until 1819.

With modifications of the château's structure, including the cobblestone entrance wide enough for his carriage, Napoleon helped make the château the place that visitors see today.

With financing from Purdue, in July 1936, a Lockheed Electra 10E was built at Lockheed Aircraft Company to her specifications which included extensive modifications to the fuselage to incorporate a large fuel tank.

With only slight modifications, this general design was continued to and including the 737-400 and-500 aircraft.

With the arrival of the Airbus A380, the airport put into place modifications works costing $ 230 million.

With suitable modifications, this result can be extended to possibly unbounded operators on infinite-dimensional spaces.

With eight weeks to go, the larger bomb, code-named ' Upkeep ', that was needed for the mission, and the modifications to the Lancasters had yet to be designed.

With permanent modifications a toaster oven can be used as a reflow oven for the purpose of soldering electronic components to circuit boards.

With open source software, generally anyone is allowed to create modifications of it, port it to new operating systems and processor architectures, share it with others or, in some cases, market it.

With the basic characteristics of the LC-6 accepted, a series of modifications followed.

With the Allegro, the makers avoided the full extent of badge engineering that defined the marketing of its predecessor, but they nevertheless introduced in September 1974 an upmarket Allegro branded as the Vanden Plas 1500 / automatic: this featured a prominent grille at the front and an interior enhanced by a range of modifications designed to attract traditionally inclined customers, including special seats upholstered in real leather with reclining backrests, ' deep ' carpets, extra sound insulation, a new instrument panel in walnut, nylon headlining and, for the luggage a fully trimmed boot / trunk.

With minor modifications, this remained the official flag until the revolution of 1979.

With these modifications, he observed for the first time computer programs that did indeed evolve in a meaningful and complex way.

With only minor modifications, the car went into-very limited-production as the model 6 20 / 25 hp.

With some modifications, the story is repeated by Constantine VII in De Administrando Imperio, followed by several generations of Byzantine historians, including John Skylitzes and John Zonaras.

With numerous additions and modifications during their history, they were the last great fortification system of antiquity, and one of the most complex and elaborate systems ever built.

With the entry into service of the new Soviet Alfa class submarine in 1972, the decision was made to accelerate the ADCAP program, which would bring significant modifications to the torpedo.

With the series of recall campaigns, Audi made several modifications ; the first adjusted the distance between the brake and accelerator pedal on automatic-transmission models.

With m modifications, this costs O ( logm ) additive lookup time.

With the birth of the Turkish Republic after the First World War, St. Sophia became a museum, and the ancient mosaics, which were plastered over by the Moslems, whose religion forbids pictures in holy places, have been restored.

With the return of our soldiers, it soon became apparent that the belief was not shared by the great majority of citizens.

Dwan also helped launch the career of two other very successful Hollywood directors, Victor Fleming, who went on to direct The Wizard of Oz and Gone With the Wind, and Marshall Neilan, who became an actor, director, writer and producer.

With Robert Morison ’ s 1672 Plantarum umbelilliferarum distribution nova it became the first group of plants for which a systematic study was published.

The term became popular again in Australia first, when George Giffen, in his memoirs ( With Bat and Ball, 1899 ), used the term as if it were well known.

With J. J. Thomson's discovery of the electron in 1897, it became clear that atoms were not the smallest building blocks of nature, but were rather composite particles.

With this title and its lands, he became the most powerful man in Portugal and one of the richest men in Europe.

With the Spartan withdrawal after Byzantion, the leadership of the Athenians became explicit.

With the development of effective anti-aircraft artillery in the period before the Second World War, military pilots, once the " knights of the air " during the First World War, became far more vulnerable to ground fire.

With the Renaissance, tyrannicide — or assassination for personal or political reasons — became more common again in Western Europe.

With the advent of gunpowder, ranged assassination ( via bombs or firearms ) became possible.

With this connection, Anubis became the patron god of embalmers: during the funerary rites of mummification, illustrations from the Book of the Dead often show a priest wearing the jackal mask supporting the upright mummy.

With it Saxony became a Constitutional monarchy and obtained a bi-cameral legistature and a responsible ministry, which replaced the old feudal estates.

With the coronation of Frederick I in 1701 as king ( in Königsberg ), Berlin became the new capital of the Kingdom of Prussia ( instead of Königsberg ); this was a successful attempt to centralize the capital in the very outspread Prussian Kingdom, and it was the first time the city began to grow.

With Parks Canada and UNESCO recognising the significance of the Burgess Shale, collecting fossils became politically more difficult from the mid-1970s.

With the coming to power of Thomas Sankara in Burkina Faso in 1983, relations between Ghana and Burkina became both warm and close.

With Gladstone's refusal Derby and Disraeli looked elsewhere and settled on Disraeli's old friend Edward Bulwer-Lytton, who became Secretary of State for the Colonies ; Derby's son Lord Stanley, succeeded Ellenborough at the Board of Control.

With the accession of Bulgaria to the European Union on January 1, 2007, Cyrillic became the third official alphabet of the EU.

With the growing amount of data, it long ago became impractical to analyze DNA sequences manually.

With ever-increasing traffic volumes funneled onto I-93 alone, the Central Artery became chronically gridlocked.

With these innings he became the second player to score two Test triple centuries, the second player to score two career quadruple centuries, the only player to achieve both these milestones, and regained the distinction of being the holder of both the record first-class individual innings and the record Test individual innings.

With its jazz sophistication, pop music and blues influence, plus improvised scats and wisecrack commentary by Wills, the band became the first superstars of the genre.

With the abolition of the metropolitan county councils in 1986, these metropolitan boroughs became independent, and continue to be so at present.

With most Bolshevik leaders either supporting Bogdanov or undecided by mid-1908 when the differences became irreconcilable, Lenin concentrated on undermining Bogdanov's reputation as a philosopher.

With open software specifications and the possibility of software licensing, new opportunities arose for software tools that then became the de facto standard, such as DOS for operating systems, but also various proprietary word processing and spreadsheet programs.