Without diagnosis and treatment, the infection can be fatal in one to six days ; mortality in untreated cases is approximately 100 %.

Without treatment, an acute attack of gout usually resolves in five to seven days.

Without treatment, episodes of acute gout may develop into chronic gout with destruction of joint surfaces, joint deformity, and painless tophi.

Without timely treatment, these new blood vessels can bleed, cloud vision, and destroy the retina.

Without special treatment after circulation is restarted, full recovery of the brain after more than 3 minutes of clinical death at normal body temperature is rare.

Without treatment, the disease is invariably fatal, with progressive mental deterioration leading to coma and death.

Without treatment, about 12-13 % of patients will spontaneously improve over time, 40-50 % will get worse and the rest will be relatively stable.

Without treatment, symptoms may worsen, leading ( in extreme cases ) to suicide attempts.

Without renouncing its " Third-worldism " position, it extended the treatment of its subjects, concentrating on international economic and monetary problems, strategic relations, the Middle-East conflict, etc.

Without effective water treatment, a cooling water system can suffer from scale formation, corrosion and fouling and may become a breeding ground for harmful bacteria such as those that cause Legionnaires ' Disease.

Without urgent treatment these result in sudden death.

Without necessarily receiving great remuneration ( pay differentials under Zhivkov were within the 5: 1 range, with the overwhelming majority of salaries being within the 3: 1 range ), Party members and DS informers received very significant perquisites which involved access to accommodation, luxury imported goods, hard currency, the ability to travel abroad, superior medical and dental treatment and unhindered entry to higher education for their children.

Without insight into what the problem is, it is much harder for behavioral therapy to be the key to the successful treatment of compulsive hoarders.

Without treatment, mortality in infants with galactosemia is about 75 %.

Without treatment, persons afflicted often appear to walk on their ankles, or on the sides of their feet.

Through its breakthrough price offers to developing country governments and leading NGOs such as Doctors Without Borders ( MSF ) and Oxfam, along with its keen participation in PEPFAR, the Global Fund, the Clinton Foundation's HIV / AIDS Initiative and other major donor programs fighting HIV / AIDS in Africa and elsewhere in the resource-poor world, Cipla has played an unparalleled leadership role in ensuring access to antiretroviral treatment ( ART ) rose from under 10, 000 on the entire African continent at the time of its $ 350 per patient per year offer in 2001, to over 8 million in the developing world by 2012.

Without treatment, children often die in the first decade of life.

Without much exchange with the ocean outside the Island, the Lake water quality is threatened by runoff from human activities in the surrounding watershed, especially from sewage treatment plants and septic tanks, ocean going ships and small craft plying the lake system.

Without treatment, the disease is often fatal.

Without treatment death usually occurs due to heart failure and respiratory weakness.

Without treatment the disease is particularly lethal in infants and young children.

Without treatment, mortality may approach 1 %, usually within six weeks of onset.

Without treatment, kidney damage occurs and death in the more severe cases.

* Sea Without Shore: A Manual of the Sufi Path, an extensive treatment of the science of tasawwuf.

Without the cohesion of a disciplined, strong formation, the individual English were easy targets.

Without a DNA sample, it is not possible to reconstruct the complete genetic makeup ( genome ) of any individual who died very long ago.

Likewise, possession of knives, batons and other any other instrument that may be considered, " Offensive Weapons " if they are possessed by an individual, in a Public Place, " Without lawful excuse ".

Without stating a standard of review in the majority opinion, the court overruled Bowers v. Hardwick ( 1986 ), declaring that the " Texas statute furthers no legitimate state interest which can justify its intrusion into the personal and private life of the individual.

Without stimulus or focus, the individual is confronted with nothingness, the meaninglessness of existence, and experiences existential anxiety.

Without competent operational and logistical planning, no amount of individual soldierly discipline or battlefield bravery could save the army from the combination of superior generalship and staff work of a talented adversary.

Without tools the individual might not be able to find the most profitable prey ( New Caledonian crows ).

Without the support of a mass movement that would have given the majority an effective voice, individual insurgents were either marginalized or coopted.

Without this, it would be impossible for any ordinary individual to attain knowledge of the Divine using mere speculation.

Without any evidence, authorities do not know whether a murder took place, or the individual decided to take a trip and tell no one, or some other criminal or non-criminal event happened.

Best known for his 1955 film Rebel Without a Cause, starring James Dean, Ray was a tortured individual at the time of the production of 55 Days at Peking, somewhat akin to the Dean persona he helped to create for Rebel.

Without the ability to engage in realpolitik, the MMA ’ s limited tenure within the party became apparent, resulting in widespread organizational and individual corruption.

Without her leadership, the Zeon fleet rapidly fell into disarray, with individual commanders recovering what suits and pilots they could, then fleeing ; others fighting to the death, believing their commander to still be alive but unable to escape.

Without long-term care insurance, the cost of providing these services may quickly deplete the savings of the individual and / or their family.

** Without the DNS Client service running: The " hosts " file is read and parsed repeatedly, by each individual application program as it makes a DNS lookup.

** Without the DNS Client service running: Any fallback to the alternative DNS servers happen locally, within each individual process that is making DNS queries.

Without the support of a mass movement that would have given the majority an effective voice, individual insurgents were either marginalized or co-opted.

Without an inventory management system, and a ticket, coupon or voucher issuing system to make the prices of the individual components appear as one price to the consumer and allow each travel service provider to know what rate to accept or charge the traveler ; dynamic packaging does not work.

Without sexual selection, an unattractive individual might find a superior mate with few deleterious mutations, and have healthy children that are likely to survive.