** Increase fat stores

** Increase uterine growth

** Increase vaginal lubrication

** Increase hepatic production of binding proteins

** Increase circulating level of factors 2, 7, 9, 10, plasminogen

** Increase platelet adhesiveness

** Increase HDL, triglyceride

** Increase cortisol, SHBG

** Increase pheomelanin, reduce eumelanin

** Increase awareness about violence against women and girls

** Increase awareness about HIV & AIDS as it relates to females.

** Increase awareness about women ’ s land rights.

** Increase awareness about women ’ s leadership, or lack of leadership in the political sphere.

** low level of " good cholesterol ";

** Metabolic syndrome ( Hyperlipidemia + HDL cholesterol level < 0. 90 mmol / L or triglyceride level > 2. 82 mmol / L ); Hypertension (> 140 / 90 mmHg ) or arteriosclerosis ;

** bile duct

** Biliary fistula: connecting the bile ducts to the skin surface, often caused by gallbladder surgery

** bile acid sequestrants

** Can progress to choledocholithiasis ( gallstones in the bile duct ) and gallstone pancreatitis ( inflammation of the pancreas )

Scientists assume that cholesterol ( from the Greek chole, meaning bile, and sterios, meaning solid ) is somehow necessary for the formation of brain cells, since it accounts for about 2% of the brain's total solid weight.

Ordinarily, the human liver synthesizes only enough cholesterol to satisfy the body's needs -- for transportation of fats and for production of bile.

The cholesterol delivered to the liver is excreted into the bile and, hence, intestine either directly or indirectly after conversion into bile acids.

Several steps in the metabolism of HDL can contribute to the transport of cholesterol from lipid-laden macrophages of atherosclerotic arteries, termed foam cells, to the liver for secretion into the bile.

Other examples of sterols are the bile acids and their conjugates, which in mammals are oxidized derivatives of cholesterol and are synthesized in the liver.

Soluble fiber binds to bile acids in the small intestine, making them less likely to enter the body ; this in turn lowers cholesterol levels in the blood.

Some types of soluble fibers bind to bile acids in the small intestine, making them less likely to enter the body ; this in turn lowers cholesterol levels in the blood.

In the upper gastrointestinal tract, these detergents consist of bile acids and di-and monoacyl glycerols which solubilize triacylglycerols and cholesterol.

# The enteric loss of bile acids results in increased synthesis of bile acids from cholesterol which in turn reduces body cholesterol.

# There might be alterations in the end-products of bile acid bacterial metabolism or the release of short chain fatty acids which are absorbed from the colon, return to the liver in the portal vein and modulate either the synthesis of cholesterol or its catabolism to bile acids.

# The prime mechanism whereby fiber influences cholesterol metabolism is through bacteria binding bile acids in the colon after the initial deconjugation and dehydroxylation.

# Other fibers, e. g., gum arabic, are associated with a significant decrease in serum cholesterol without increasing fecal bile acid excretion.

Bile is a composition of the following materials: water ( 85 %), bile salts ( 10 %), mucus and pigments ( 3 %), fats ( 1 %), inorganic salts ( 0. 7 %) and cholesterol ( 0. 3 %).

* The cholesterol contained in bile will occasionally accrete into lumps in the gallbladder, forming gallstones.

The mechanism appears to be an increase of viscosity in the intestinal tract, leading to a reduced absorption of cholesterol from bile or food.

Melatonin presence in the gallbladder has many protective properties, such as converting cholesterol to bile, preventing oxidative stress, and increasing the mobility of gallstones from the gallbladder.

The large, yellow Calculus ( medicine ) | calculus probably comprises cholesterol, while the green-to-brown stones suggest Bilin ( biochemistry ) | bile pigments, such as biliverdin and stercobilin.

A lack of melatonin could significantly contribute to gallbladder stones, as melatonin inhibits cholesterol secretion from the gallbladder, enhances the conversion of cholesterol to bile, and is an antioxidant, which is able to reduce oxidative stress to the gallbladder.