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Page "Estrogen" ¶ 37
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** and Increase
** Increase fat stores
** Increase uterine growth
** Increase vaginal lubrication
** Increase hepatic production of binding proteins
** Increase circulating level of factors 2, 7, 9, 10, plasminogen
** Increase HDL, triglyceride
** Increase cortisol, SHBG
** Increase cholesterol in bile
** Increase pheomelanin, reduce eumelanin
** Increase awareness about violence against women and girls
** Increase awareness about HIV & AIDS as it relates to females.
** Increase awareness about women ’ s land rights.
** Increase awareness about women ’ s leadership, or lack of leadership in the political sphere.

** and platelet
** The accumulation of platelets to the site of a wound to form a platelet plug or a thrombus
** platelet count < 80, 000 / mm < sup > 3 </ sup > or 50 % drop from maximum in chronically thrombocytopenic patients, OR
** Decreased platelet count (< 50 x 10 < sup > 9 </ sup >/ L )
** Grey platelet syndrome
** platelet GPIb-receptor
** HELLP is characterized by hemolysis on peripheral blood smear with serum lactate dehydrogenase > 600 IU / L ; serum aspartate aminotransferase > 70 IU / L ; and platelet count < 100, 000 / μL.
** " The diagnosis of HELLP syndrome required the presence of thrombocytopenia ( perinatal platelet nadir ≤ 150, 000 cells / μL ), evidence of hepatic dysfunction ( increased aspartate aminotransferase level of ≥ 40 IU / L, increased alanine aminotransferase level of ≥ 40 IU / L, or both, with increased lactate dehydrogenase level of ≥ 600 IU / L ), and evidence of hemolysis ( increased LDH level, progressive anemia )...."
** " Class 1 HELLP syndrome featured severe thrombocytopenia with a platelet nadir of ≤ 50, 000 cells / μL, class 2 HELLP syndrome featured moderate thrombocytopenia with a platelet nadir between > 50, 000 and ≤ 100, 000 cells / μL, and class 3 HELLP syndrome featured mild thrombocytopenia with a platelet nadir between > 100, 000 and ≤ 150, 000 cells / μL.
** Myelotoxicity or bone marrow suppression, potentially leading to thrombocytopenia or blood platelet deficiency and / or leukopenia or white blood cell ( WBC ) deficiency
** low platelet counts ( leading to easy bruising and bleeding )
** Decreased platelet count causing increased risk of bleeding

Increase and platelet
Increase platelet counts can be due to a number of disease processes:

platelet and adhesiveness
The antithrombotic effect of dextran is mediated through its binding of erythrocytes, platelets, and vascular endothelium, increasing their electronegativity and thus reducing erythrocyte aggregation and platelet adhesiveness.

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