* 1475 – The Treaty of Picquigny ends a brief war between France and England.

Cesare Borgia (;, ; 13 September 1475 or April 1476 – 12 March 1507 ), Duke of Valentinois, was an Italian condottiero, nobleman, politician, and cardinal.

* 1521 – Pope Leo X ( b. 1475 )

* 1475 – Thomas Murner, German writer ( d. c. 1537 )

Diego de Almagro, ( c. 1475 – July 8, 1538 ), also known as El Adelantado and El Viejo ( The Elder ), was a Spanish conquistador and a companion and later rival of Francisco Pizarro.

* 1475 – Pope Leo X ( d. 1521 )

* Thomas Murner ( 1475 – 1537 )

Mai Ali Gazi ibn Dunama ( c. 1475 – 1503 ) defeated the Bilala, reestablishing complete control of Kanem.

* 1475 – Stephen III of Moldavia defeats the Ottoman Empire at the Battle of Vaslui.

Annunciation ( Leonardo ) | Annunciation ( 1475 – 1480 )— Uffizi, is thought to be Leonardo's earliest complete work.

* 1475 – Michelangelo, Italian artist and sculptor ( d. 1564 )

Michelangelo di Lodovico Buonarroti Simoni ( 6 March 1475 – 18 February 1564 ), commonly known as Michelangelo (), was an Italian Renaissance sculptor, painter, architect, poet, and engineer who exerted an unparalleled influence on the development of Western art.

Moreover, from 1502 to 1503 he witnessed the brutal reality of the state-building methods of Cesare Borgia ( 1475 – 1507 ) and his father Pope Alexander VI, who were then engaged in the process of trying to bring a large part of central Italy under their possession.

* 1475 – Princess Anne of York, Countess of Surrey ( d. 1511 )

Paolo Uccello ( 1397 – 10 December 1475 ), born Paolo di Dono, was an Italian painter and a mathematician who was notable for his pioneering work on visual perspective in art.

)- 1475, he studied civil law at the university of Pavia, and later went to Ferrara ( 1475 – 1479 ), where he became the protégé of Prince d ' Este of Ferrara, was a pupil of Theodor Gaza and attended lectures by the famous Battista Guarino.

* Dirk Bouts ( – 1475 ), Early Netherlandish painter.

* Petrus Christus ( – 1475 / 1476 ), Early Netherlandish painter.

* February 18 – Michelangelo Buonarroti, Italian artist, architect and sculptor ( b. 1475 )

* probable – Filippo de Lurano, Italian composer ( b. 1475 )

* July 4 – Khair ad Din " Barbarossa ", corsair ruler of Algiers ( b. 1475 )

* December 1 – Pope Leo X ( b. 1475 )

* September 4 – Johann Dietenberger, German theologian ( b. c. 1475 )

* March 12 – Cesare Borgia, Italian general and statesman killed by an unknown assassin .( b. 1475 )

* Cesare Borgia ( 1475 – 1507 )

* Cesare ( born 1475 );

He was born in Rome — in either 1475 or 1476 — the son of Cardinal Rodrigo de Lanzol y Borgia, soon to become Pope Alexander VI, and his mistress Vannozza dei Cattanei, about whom information is sparse.

** Sebastiano Serlio, Italian architect ( b. 1475 )

** Masuccio Salernitano, Italian poet ( d. 1475 )

A famous civil engineer of pound locks in Europe was the Italian Bertola da Novate ( c. 1410 – 1475 ), who constructed 18 of them on the Naviglio di Bereguardo ( part of the Milan canal system sponsored by Francesco Sforza ) between the years 1452 and 1458.

Masuccio Salernitano ( 1410 – 1475 ), born Tommaso Guardati, was an Italian poet.

The printed De honesta voluptate (" On honourable pleasure "), first published in 1475, is one of the first cookbooks based on Renaissance ideals, and, though it is as much a series of moral essays as a cookbook, has been described as " the anthology that closed the book on medieval Italian cooking ".

* De honesta voluptate et valetudine ( 1475 ) by Bartolomeo Platina-the first cookbook printed in a native language ( Italian ) in 1487

Italian exegete, philosopher, and physician ; born at Cesena about 1475 ; died at Bologna in 1550.

* Paolo Uccello ( Italian, 1397 – 1475 ) Schematic use of perspective / foreshortening

* Michelangelo ( Italian, 1475 – 1564 ) Acclaimed great Renaissance sculptor

* Bernardino Luini ( Italian, 1475 – 1532 )

* Marcantonio Raimondi ( Italian, 1475 – 1534 )

Theodorus Gaza or Theodore Gazis ( c. 1398 – c. 1475 ) ( Greek: Θεόδωρος Γαζῆς, Theodoros Gazis ; Italian: Teodoro Gaza ; Latin: Theodorus Gazes, gen .: Theodori Gazae ), also called by the epithet Thessalonicensis ( in Latin ) and Thessalonikeus ( in Greek ), was a Greek humanist and translator of Aristotle, one of the Greek scholars who were the leaders of the revival of learning in the 15th century ( the Palaeologan Renaissance ).

Sebastiano Serlio ( 6 September 1475 – 1554 ) was an Italian Mannerist architect, who was part of the Italian team building the Palace of Fontainebleau.

Philosophy and Mathematics: Urbanus Averroista, commentator of Averroes ; Andrew Zaini ( 1423 ); Paul Albertini ( 1475 ), better known as Paolo Veneto ; Philip Mucagatta ( 1511 ); John Baptist Drusiani ( 1656 ), the " Italian Archimedes "; Benedict Canali ( 1745 ); Raymond Adami ( 1792 ); Angelus Ventura ( 1738 ).

Filippo de Lurano ( also Luprano, or Lorano ) ( c. 1475 – after 1520 ) was an Italian composer of the Renaissance.

The Annunciation is a painting by Italian Renaissance artists Leonardo da Vinci and Andrea del Verrocchio, dating from circa 1472 – 1475 and housed in the Uffizi Gallery of Florence, Italy.