* 1519 – Panama City, Panama, is founded.

Category: People of the Polish – Teutonic War 1519 – 1521 ( German side )

* 1519 – Spanish conquistador Hernán Cortés establishes a settlement at Veracruz, Mexico.

* 1480 – Lucrezia Borgia, Florentine ruler and daughter of Pope Alexander VI ( d. 1519 )

* 1519 – Ferdinand Magellan's five ships set sail from Seville to circumnavigate the globe.

* 1574 – Cosimo I de ' Medici, Grand Duke of Tuscany ( b. 1519 )

Vasco Núñez de Balboa ( c. 1470 – 1519 ), Spanish explorer

Journal of the American Society for Information Science and Technology, 60 ( 8 ), 1519 – 1536

Crankshafts were also described by Konrad Kyeser ( d. 1405 ), Leonardo da Vinci ( 1452 – 1519 ) and a Dutch " farmer " by the name Cornelis Corneliszoon van Uitgeest in 1592.

* 1591 – Pope Innocent IX ( b. 1519 )

Their contemporary, Leonardo da Vinci ( 1452 – 1519 ) said,

* Francesco II Gonzaga, Marquess of Mantua ( 1466 – 1519 )

The classic rules of sliding friction were discovered by Leonardo da Vinci ( 1452 – 1519 ), but remained unpublished in his notebooks.

* 1519 – René of Châlon, ( d. 1544 )

* Maximilian ( 1459 – 1519 ), Holy Roman Emperor, married

* Leonardo da Vinci ( Italian, 1452 – 1519 ).

* 1519 – Cosimo I de ' Medici, Grand Duke of Tuscany ( d. 1574 )

* 1560 – Imagawa Yoshimoto, Japanese daimyo ( b. 1519 )

* 1519 – Theodore Beza, French theologian ( d. 1605 )

Johann Tetzel ( 1465 – 11 August 1519 ) was a German Dominican preacher known for selling indulgences.

Maximilian I, Holy Roman Emperor ( 1459 – 1519 ) is often referred to as the last true knight.

Leonardo di ser Piero da Vinci ( ) ( April 15, 1452 – May 2, 1519, Old Style ) was an Italian Renaissance polymath: painter, sculptor, architect, musician, scientist, mathematician, engineer, inventor, anatomist, geologist, cartographer, botanist, and writer.

Lucrezia Borgia (; 18 April 1480 – 24 June 1519 ) was the illegitimate daughter of Rodrigo Borgia, the powerful Renaissance Valencian who later became Pope Alexander VI, and Vannozza dei Cattanei.

After his father was killed in 1563, he became Duke of Vendôme at the age of 10, with Admiral Gaspard de Coligny ( 1519 – 1572 ) as his regent.

Gaspard de Coligny ( 16 February 1519 – 24 August 1572 ), Seigneur ( Lord ) de Châtillon, was a French nobleman and admiral, best remembered as a disciplined Huguenot leader in the French Wars of Religion.

Born at Châtillon-sur-Loing in 1519, Gaspard came to court at the age of 22 and began a friendship with François of Guise.

*** Gaspard II de Coligny ( 1519 – 1572 ), Seigneur ( Lord ) de Châtillon, admiral of France and Protestant leader, whose children included

On August 15, 1519, Pedrarias, having abandoned Santa María la Antigua del Darién, moved the capital of Castilla del Oro with all its organizational institutions to the Pacific Ocean's coast and founded Nuestra Señora de la Asunción de Panamá ( present day Panama City ), the first European settlement on the shores of the Pacific.

In 1487 he married his elder son Franceschetto Cybo ( d. 1519 ) to Maddalena de ' Medici ( 1473 – 1528 ), the natural daughter of Lorenzo de ' Medici, who in return obtained the cardinal's hat for his thirteen-year-old son Giovanni, later Pope Leo X.

* 1492 – Lorenzo de ' Medici, Duke of Urbino ( d. 1519 )

* 1519 – Ferdinand Magellan sets sail from Sanlúcar de Barrameda with about 270 men on his expedition to circumnavigate the globe.

More also engaged in controversies, most notably with the French poet Germain de Brie, which culminated in the publication of de Brie's attack Antimorus ( 1519 ).

* Juan de Flandes ( 1460 – 1519 ), Early Netherlandish painter who was active in Spain from 1496 to 1519 at the court of Isabella I of Castile.

* September 12 – Lorenzo II de ' Medici, Duke of Urbino ( d. 1519 )

* April 21 – Cosimo I de ' Medici, Grand Duke of Tuscany ( b. 1519 )

* September 17 – Pedro Menéndez de Avilés, first Spanish Governor of Florida ( b. 1519 )

de: 1519

The area was explored in more detail in 1516 by Diego de Miruelo and in 1519 by Alonso Álvarez de Pineda.

* January 5 – Catherine de ' Medici, queen of Henry II of France ( b. 1519 )

** Alonso Álvarez de Pineda, Spanish explorer and cartographer ( d. 1519 )

** Vasco Núñez de Balboa, Spanish conquistador ( approximate date ; d. 1519 )

Theodore Beza ( Théodore de Bèze or de Besze ) ( June 24, 1519 – October 13, 1605 ) was a French Protestant Christian theologian and scholar who played an important role in the Reformation.