Adenylate cyclase (, also known as adenylyl cyclase, adenyl cyclase or AC ) is an enzyme with key regulatory roles in nearly all cells.

Adenylate cyclase is dually regulated by G proteins ( Gs stimulating activity and Gi inhibiting it ), and by forskolin, as well as other isoform-specific effectors:

* Interactive 3D views of Adenylate cyclase at

* Adenylate cyclase, a lyase enzyme

# G protein stimulates Adenylate cyclase

# redirect Adenylate cyclase

Magnesium is a cofactor for Adenylate cyclase.