* Ataxia, or difficulty walking

Ataxia can be induced as a result of severe acute radiation poisoning with an absorbed dose of more than 30 Grays.

Ataxia may depend on hereditary disorders consisting of degeneration of the cerebellum and / or of the spine ; most cases feature both to some extent, and therefore present with overlapping cerebellar and sensory ataxia, even though one is often more evident than the other.

* Episodic Ataxia ( EA ), characterized by sporadic bouts of severe discoordination with or without myokymia, and can be provoked by stress, startle, or heavy exertion such as exercise.

For example, a GAA triplet expansion in the first intron of the X25 gene appears to interfere with transcription, and causes Friedreich Ataxia ( Bidichandani 1998 ).

He has also appeared on fellow DC post-punkers Decahedron's debut album Disconnection_Imminent, as well as on a one shot project with John Frusciante ( formerly ) of the Red Hot Chili Peppers and current Red Hot Chili Peppers guitarist, Josh Klinghoffer known as Ataxia.

Ataxia and neurological signs then develop, and affected sheep struggle to keep up with the flock.

Numerous advocacy groups such as the National Organization for Rare Disorders, Global Genes Project, Children's Rare Disease Network, Abetalipoproteinemia Collaboration Foundation, Zellweger Baby Support Network, and the Friedreich's Ataxia Research Alliance have been founded in order to advocate on behalf of patients suffering from rare diseases with a particular emphasis on diseases that afflict children.

He has also worked with John Frusciante and Josh Klinghoffer as the group Ataxia, releasing two albums: Automatic Writing ( 2004 ) and AW II ( 2007 ).

In 1990, Allison helped found the Bob Allison Ataxia Research Center at the University of Minnesota along with his wife Betty, sons Mark, Kirk, and Kyle, and former Twins ' teammates Jim Kaat and Frank Quilici.

Ataxia oculomotor apraxia type 1 ( AOA1 ) is an autosomal recessive disorder similar to A-T in manifesting increasing problems with coordination and oculomotor apraxia, often at a similar age to those having A-T.

Ataxia oculomotor apraxia type 2 ( AOA2 ) is an autosomal recessive disorder also similar to A-T in manifesting increasing problems with coordination and peripheral neuropathy, but oculomotor apraxia is present in only half of affected individuals.

John Frusciante ( Red Hot Chili Peppers, Ataxia ) performs the first two guitar solos with Omar Rodríguez-López performing the last solo.

* Ex-Red Hot Chili Peppers guitarist John Frusciante, Fugazi bassist Joe Lally and Red Hot Chili Peppers guitarist Josh Klinghoffer formed a brief project named Ataxia, releasing two albums ; Automatic Writing and AW II ; with lengthy tracks based largely around improvisational guitar set against a steady, unchanging bassline and drum beat.

Ataxia telangiectasia mutated has been shown to interact with RAD17, RBBP8, RAD51, DNA-PKcs, RRM2B, FANCD2, Nibrin, TERF1, BRCA1, Abl gene, TP53BP1, MRE11A, P53, Bloom syndrome protein, SMC1A and RHEB.

An estimated 150, 000 people in the United States are diagnosed with Ataxia, SCA's are the largest group of this hereditary, progressive, degenerative and often fatal neurodegenerative disorders.

Ataxia is a non-specific clinical manifestation implying dysfunction of the parts of the nervous system that coordinate movement, such as the cerebellum.

* Ataxia – This is a neurological clinical sign, consisting of unsteady and clumsy motion of the limbs and torso, due to failure of gross muscle movement coordination, most evident on standing and walking.

Ataxia ( from Greek α-negative prefix +-τάξις = " lack of order "), is a neurological sign consisting of lack of voluntary coordination of muscle movements.

The International Cooperative Ataxia Rating Scale ( ICARS ) is one of the most widely used and has been proven to have very high reliability and validity.

Ataxia is also the name of a disease in the Elder Scrolls console and PC games.

Pes cavus is sometimes — but not always — connected through Hereditary Motor and Sensory Neuropathy Type 1 ( Charcot-Marie-Tooth disease ) and Friedreich's Ataxia ; many other cases of pes cavus are natural.

Ataxia telangiectasia ( A-T ) ( also referred to as Louis – Bar syndrome ) is a rare, neurodegenerative, inherited disease causing severe disability.

A-T is caused by mutations in the ATM ( Ataxia Telangiectasia Mutated ) gene which was cloned in 1995.

** Friedreich Ataxia – GAA ( Note: Friedreich ataxia does not usually exhibit anticipation because it is an autosomal recessive disorder.

Ataxia telangiectasia mutated ( ATM ) is a serine / threonine protein kinase that is recruited and activated by DNA double-strand breaks.

The protein is named for the disorder Ataxia telangiectasia caused by mutations of ATM.

Ataxia telangiectasia ( AT ) is a rare human disease characterized by cerebellar degeneration, extreme cellular sensitivity to radiation and a predisposition to cancer.

The dweller at p is last to hear about a new cure, the slowest to announce to his neighbors his urgent distresses, the one who goes the farthest to trade, and the one with the greatest difficulty of all in putting over an idea or getting people to join him in a cooperative effort.

Analogously, anyone who argues that Einstein's theory of gravitation is simpler than Newton's, must say rather more to explain how it is that the latter is mastered by student-physicists, while the former can be managed ( with difficulty ) only by accomplished experts.

There's a man who never goes by the ordinary road but still arrives at his goal, who gratuitously gets himself into difficulty in order to get out of it with eclat, in a word a man who creates monsters for himself in order to appear a Hercules in destroying them ''.

Uncle Randolph and Joel had replanted the bottom lands with difficulty, for more of the slaves, including Annie, had sneaked off when the soldiers broke camp.

It should be kept in mind that the ease or difficulty with which a town or city can convert to the proposed plan is directly dependent upon the financial condition of that town or city.

Placing missiles in submarines, on barges, railroads, highways, surface vessels and in the air provides them with passive protection by taking advantage of the gravest weakness of long-range ballistic missiles today -- the extreme difficulty of destroying a mobile or moving target with such weapons.

Under the circumstances, I had difficulty keeping up with the conversation on the phone, but when I hung up I was reasonably certain that Francesca had wanted to remind me of our town meeting the next evening, and how important it was that Hank and I be there.

Inability to care for the other children, difficulty in feeding the babies, who seemed colicky, bone-weary fatigue, repeated crying episodes, and short tempers reflected the family's helplessness in coping with the stressful situation.

While we had expected that compulsive children in the unstructured school setting would have difficulty when compared to those in the structured, we were surprised to find that the achievement of the high compulsives within the schools where the whole-word method is used in beginning reading compares favorably with that of the low compulsives.

Serious difficulty arose with the advent of Substantive Due Process.

However, this difficulty is not too serious if it is realized that a surveying team can establish a true north base line with a few days' work.

The accumulated information on this point shows that first intercourse, even when it is achieved with minimum pain or difficulty, is seldom an overwhelming sexual experience to a woman.

In itself there is nothing wrong with this form of `` participation '': the only difficulty on the Catholic campus is that those faculty members who are in a position to implement policy, i.e., members of the religious community which owns and administers the institution, have their own eating arrangements.

What's happening in textiles can be handwriting on the wall for other lines having difficulty competing with imports from low-wage countries.

AT promotes greater independence by enabling people to perform tasks that they were formerly unable to accomplish, or had great difficulty accomplishing, by providing enhancements to, or changing methods of interacting with, the technology needed to accomplish such tasks.

Individuals with cerebellar ataxia could also display instability of gait, difficulty with eye movements, dysarthria, dysphagia, hypotonia, dysmetria and dysdiadochokinesia.

The standard is whether " removing barriers " ( typically defined as bringing a condition into compliance with the ADAAG ) is " readily achievable ", defined as " easily accomplished without much difficulty or expense ".

From there Alaric escaped with difficulty, and not without some suspicion of connivance by Stilicho, who supposedly had again received orders to depart.

Royal forces crushed a revolt in Galloway in 1235 without difficulty ; nor did an invasion attempted soon afterwards by its exiled leaders meet with success.

* Anomic aphasia, also known as Anomia, is another type of aphasia proposed under what is commonly known as the Boston-Neoclassical model, which is essentially a difficulty with naming.

An individual with global aphasia will have difficulty understanding both spoken and written language and will also have difficulty speaking.

* Isolation Aphasia, also known as Mixed Transcortical Aphasia, is a type of disturbance in language skill that causes the inability to comprehend what is being said to you or the difficulty in creating speech with meaning without affecting the ability to recite what has been said and to acquire newly presented words.