Ataxia ( from Greek α-negative prefix +-τάξις = " lack of order "), is a neurological sign consisting of lack of voluntary coordination of muscle movements.

* Ataxia – This is a neurological clinical sign, consisting of unsteady and clumsy motion of the limbs and torso, due to failure of gross muscle movement coordination, most evident on standing and walking.

* OMA, Opsoclonus Myoclonus Ataxia, a neurological disorder better known as Opsoclonus myoclonus syndrome

Ataxia oculomotor apraxia type 2 ( AOA2 ) is an autosomal recessive disorder also similar to A-T in manifesting increasing problems with coordination and peripheral neuropathy, but oculomotor apraxia is present in only half of affected individuals.

Ataxia was observed to last for about 8 weeks in the affected animals.

Ataxia can be induced as a result of severe acute radiation poisoning with an absorbed dose of more than 30 Grays.

Ataxia may depend on hereditary disorders consisting of degeneration of the cerebellum and / or of the spine ; most cases feature both to some extent, and therefore present with overlapping cerebellar and sensory ataxia, even though one is often more evident than the other.

* Episodic Ataxia ( EA ), characterized by sporadic bouts of severe discoordination with or without myokymia, and can be provoked by stress, startle, or heavy exertion such as exercise.

For example, a GAA triplet expansion in the first intron of the X25 gene appears to interfere with transcription, and causes Friedreich Ataxia ( Bidichandani 1998 ).

He has also appeared on fellow DC post-punkers Decahedron's debut album Disconnection_Imminent, as well as on a one shot project with John Frusciante ( formerly ) of the Red Hot Chili Peppers and current Red Hot Chili Peppers guitarist, Josh Klinghoffer known as Ataxia.

Numerous advocacy groups such as the National Organization for Rare Disorders, Global Genes Project, Children's Rare Disease Network, Abetalipoproteinemia Collaboration Foundation, Zellweger Baby Support Network, and the Friedreich's Ataxia Research Alliance have been founded in order to advocate on behalf of patients suffering from rare diseases with a particular emphasis on diseases that afflict children.

He has also worked with John Frusciante and Josh Klinghoffer as the group Ataxia, releasing two albums: Automatic Writing ( 2004 ) and AW II ( 2007 ).

In 1990, Allison helped found the Bob Allison Ataxia Research Center at the University of Minnesota along with his wife Betty, sons Mark, Kirk, and Kyle, and former Twins ' teammates Jim Kaat and Frank Quilici.

* Ataxia ( difficulty with control of movement ) that is apparent early but worsens in school to pre-teen years

Ataxia oculomotor apraxia type 1 ( AOA1 ) is an autosomal recessive disorder similar to A-T in manifesting increasing problems with coordination and oculomotor apraxia, often at a similar age to those having A-T.

John Frusciante ( Red Hot Chili Peppers, Ataxia ) performs the first two guitar solos with Omar Rodríguez-López performing the last solo.

* Ex-Red Hot Chili Peppers guitarist John Frusciante, Fugazi bassist Joe Lally and Red Hot Chili Peppers guitarist Josh Klinghoffer formed a brief project named Ataxia, releasing two albums ; Automatic Writing and AW II ; with lengthy tracks based largely around improvisational guitar set against a steady, unchanging bassline and drum beat.

Ataxia telangiectasia mutated has been shown to interact with RAD17, RBBP8, RAD51, DNA-PKcs, RRM2B, FANCD2, Nibrin, TERF1, BRCA1, Abl gene, TP53BP1, MRE11A, P53, Bloom syndrome protein, SMC1A and RHEB.

An estimated 150, 000 people in the United States are diagnosed with Ataxia, SCA's are the largest group of this hereditary, progressive, degenerative and often fatal neurodegenerative disorders.

Ataxia is a non-specific clinical manifestation implying dysfunction of the parts of the nervous system that coordinate movement, such as the cerebellum.

The International Cooperative Ataxia Rating Scale ( ICARS ) is one of the most widely used and has been proven to have very high reliability and validity.

Ataxia is also the name of a disease in the Elder Scrolls console and PC games.

As in the game Oblivion, Ataxia makes your character's muscles have a lack of coordination.

These include Werner syndrome, Ataxia telangiectasia, Ataxia-telangiectasia like disorder, Bloom syndrome, Fanconi anemia, and Nijmegen breakage syndrome.

* Marie-Foix-Alajouanine syndrome, Ataxia of the cerebellum in advanced age, frequently due to abuse of alcohol.

Pes cavus is sometimes — but not always — connected through Hereditary Motor and Sensory Neuropathy Type 1 ( Charcot-Marie-Tooth disease ) and Friedreich's Ataxia ; many other cases of pes cavus are natural.

* Marie-Foix-Alajouanine syndrome: Ataxia of the cerebellum in advanced age.

The causes of dysarthria can be many, including toxic, metabolic, degenerative diseases ( such as Parkinsonism, ALS, Huntington's Disease, Niemann Pick disease, Ataxia etc.

Ataxia telangiectasia ( A-T ) ( also referred to as Louis – Bar syndrome ) is a rare, neurodegenerative, inherited disease causing severe disability.

Ataxia refers to poor coordination and telangiectasia to small dilated blood vessels, both of which are hallmarks of the disease.

A-T is caused by mutations in the ATM ( Ataxia Telangiectasia Mutated ) gene which was cloned in 1995.

** Friedreich Ataxia – GAA ( Note: Friedreich ataxia does not usually exhibit anticipation because it is an autosomal recessive disorder.

* FARA The Friedreich's Ataxia Research Alliance at www. cureFA. org

The above symptoms, especially fever, respiratory signs, neurological signs, and thickened footpads found in unvaccinated dogs strongly indicate canine distemper.

Clinical signs of the chronic phase include weight loss, pale gums due to anemia, bleeding due to thrombocytopenia, vasculitis, lymphadenopathy, dyspnea, coughing, polyuria, polydipsia, lameness, ophthalmic diseases such as retinal hemorrhage and anterior uveitis, and neurological disease.

A neurological exam may show signs of:

On the other hand, HSP is classified as complex or complicated when associated with other neurological signs, including ataxia, mental retardation, dementia, extrapyramidal signs, visual dysfunction or epilepsy, or with extraneurological signs.

Complicated forms are diagnosed as HSPs when pyramidal signs are the predominant neurological characteristic.

* Grade 3: neck complaints plus neurological signs such as decreased deep tendon reflexes, weakness and sensory deficits.

In horses, infection usually causes pulmonary oedema, congestion and / or neurological signs.

Cerebral babesiosis is suspected in vivo when neurological signs ( often severe ) are seen in cattle that are positive for B. bovis on blood smear, but this has yet to be proven scientifically.

**** Focal neurological signs

In the past, the patient would often be asked to lie on his / her back for at least six hours and be monitored for signs of neurological problems, though there is no scientific evidence that this provides any benefit.

A patient who has contracted this illness usually displays subacute symptoms, including altered mental status, headaches, fever, neck stiffness, seizures, focal neurological signs ( such as cranial nerve palsies and coma ), all leading to death within one week to several months.

Other neurological signs may include myoclonus ( involuntary twitching of a muscle or group of muscles ), asterixis ( abrupt loss of muscle tone, quickly restored ), nystagmus ( rapid, involuntary eye movement ), tremor, seizures, jactitation ( restless picking at things characteristic of severe infection ), and respiratory abnormalities such as Cheyne-Stokes respiration ( cyclic waxing and waning of tidal volume ), apneustic respirations and post-hypercapnic apnea.

Highly virulent strains correlate with acute, obvious disease and high mortality, including neurological signs and hemorrhages within the skin.

Soft signs are broader, nonspecific neurological impairments, or symptoms, such as impaired fine motor skills, neurosensory hearing loss, poor gait, clumsiness, poor eye-hand coordination.

* There is no focal neurological deficit ( see focal neurological signs )

In excluding neurological disease, the neurologist has traditionally relied partly on the presence of positive signs of conversion disorder — certain aspects of the presentation that were thought to be rare in neurological disease, but common in conversion.

The validity of many of these signs has been questioned, however, by a study showing that they also occurred in neurological disease.

One of Charcot's greatest legacies as a clinician is his contribution to the development of systematic neurological examination, correlating a set of clinical signs with specific lesions.

Diplopia is often one of the first signs of a systemic disease, particularly to a muscular or neurological process, and it may disrupt a person ’ s balance, movement, and / or reading abilities.