These conclusions were, however, questioned by another review, which found that clozapine, amisulpride, and olanzapine and risperidone were more effective Clozapine has appeared to be more effective than other atypical antipsychotics, although it has previously been banned due to its potentially lethal side effects.

Clozapine is an effective treatment for those who respond poorly to other drugs, but it has the potentially serious side effect of agranulocytosis ( lowered white blood cell count ) in 1 – 4 %.

The 2003 NICE ECT guidelines do not recommend ECT for schizophrenia, and this has been supported by meta-analytic evidence showing no or little benefit versus placebo, or in combination with antipsychotic drugs, including Clozapine.

Clozapine is an effective treatment for those who respond poorly to other drugs, but it has the potentially serious side effect of agranulocytosis ( lowered white blood cell count ) in 1 – 4 %.

* Clozapine ( Clozaril )-Requires weekly to biweekly complete blood count due to risk of agranulocytosis.

Clozapine can cause agranulocytosis ( which is decreased number of white blood cells ), Barker ( 2003 ) explains that a person on clozapine will have to go through rigorous blood monitoring.

In cases when severely ill patients do not respond to standard treatment, Clozapine may be prescribed although it may cause drowsiness, sedation, excessive salivation, tachycardia, dizziness, seizures and agranulocytosis.

Keefe ; Clarence E. Davis ; Joanne Severe ; John K. Hsiao 2006 for the CATIE Investigators Effectiveness of Clozapine Versus Olanzapine, Quetiapine, and Risperidone in Patients With Chronic Schizophrenia Who Did Not Respond to Prior Atypical Antipsychotic Treatment Am J Psychiatry 2006 ; 163: 600-610.

Since 1944 he has also conducted regularly at the San Francisco Opera, where he made his debut with a memorable performance of Verdi's Falstaff.

Though he is also concerned with freeing dance from pedestrian modes of activity, Merce Cunningham has selected a very different method for achieving his aim.

There was also a lesson, one that has served ever since to keep Americans, in their conflicts with one another, from turning from the ballot to the bullet.

I think that we are here also talking of the kind of fear that a young boy has for a group of boys who are approaching at night along the streets of a large city.

In addition, our way of dealing directly with natural phenomena has also changed.

also he is a drunk, and has lost his job on that account.

Today the private detective will also investigate insurance claims or handle divorce cases, but his primary function remains what it has always been, to assist those who have money in their unending struggle with those who have not.

Evidence is plentiful that early and later also he has been indebted to the Gothic romancers, who deal in extravagant horror, to the symbolists writing at the end of the preceding century, and in particular to the stream-of-consciousness novelists, Henry James and James Joyce among them.

It is, however, a disarming disguise, or perhaps a shield, for not only has Mercer proved himself to be one of the few great lyricists over the years, but also one who can function remarkably under pressure.

He has also enjoyed a successful career as an entertainer ( his records have sold in the millions ) and is a sharp businessman.

He has also an extraordinary conscience.

Mercer has also written both music and lyrics for several songs.

A slow and painful trend toward unification has taken hold, a trend which may at any time be arrested and reversed but which may also lead to a binding federation of Europe.

His successor, Secretary Goldberg, also has been guessing wrong on a drop in the unemployment rate which has been holding just under 7 per cent for the last 11 months.

St. Louis county under its present leadership also has largely closed its eyes to the need for governmental reform, and permitted parochial interests to take priority over area-wide interests.

Since the Connally amendment has the effect of giving the same right to the other party to a dispute with the United States, it also prevents us from using the court effectively.

But a realization that each group has much of substance to learn from the other also developed, and a strong conviction grew that each had insights and dimensions to contribute to ethically acceptable solutions of urgent political issues.

And so, let us remember on this day not only to thank the Almighty Who gave hope and courage to the Pilgrims, but also to place our trust in Him that He will continue to protect us in the future as He has in the past.

It has also been observed, in helium 2, that large discrepancies can exist between surface vapor pressures and those pressures measured by a vapor pressure thermometer.

I am also pleased to note that Mr. John B. Oakes, a member of the Times staff since 1946, has been appointed as editorial page editor.

Since then, there has been a notable increase in the number of stations and also the accumulation of additional data and the development of new techniques for using it, leading to a better understanding of propagation phenomena.

The president has little influence in day-by-day curricular changes, but if he looks ahead two, three, or five years to anticipate issues and throw out challenging ideas, he can open the way for innovation, and he can also have a great deal to say as to what path it will take.

If the superintendents do not receive more cooperation from Handlers, it has been suggested that licensed Judges also be qualified to judge this Class.

A beginner's shotgun has also been introduced this year.

When necessary, we should make it clear that countries which choose to derive marginal advantages from the cold war or to exploit their potential for disrupting the security of the world will not only lose our sympathy but also risk their own prospects for orderly development.

While the method of interviewing a small number of companies was appealing because of the opportunity it might have furnished to probe fully the reasons and circumstances of a company's practices and opinions, it also involved the risk of paying undue attention to the unique and peculiar problems of just a few individual companies.

Can the church risk assuming that the `` folly '' of men is as dear to God as their `` wisdom '', or, as is also commonly implied, that `` the foolishness of God '' and `` the foolishness of men '' are simply two ways of talking about the same thing??

Mr. Philip Toynbee affirms at one point that if he shared the anticipations of Orwell in Nineteen Eighty-Four, if he believed Communism was not only evil but `` also irredeemably evil '', then he might `` think it right to do anything rather than to take the risk of a communist world.

The term also broadly refers to any enterprise that is potentially fraught with physical, financial or psychological risk, such as a business venture, a love affair, or other major life undertakings.

McCullough and Farah also state that the risk of acquiring cancer rises almost five times for users of alcohol-containing mouthwash who neither smoke nor drink ( with a higher rate of increase for those who do ).

The player can also send their ship into hyperspace, causing it to disappear and reappear in a random location on the screen ( with the risk of self-destructing or appearing on top of an asteroid ).

Their use in the first trimester is also associated with a risk of major congenital malformations, particularly affecting the cardiovascular and central nervous systems.

It is believed that there is a greater risk of developing tardive dyskinesia with the older, typical antipsychotic drugs, although the newer antipsychotics are now also known to cause this disorder.

Some critics have also analyzed the use of alleged front organizations and conflicted patient " advocacy " groups funded by pharmaceutical companies that seek to set the mental health agenda, including the use of the law to force people to take antipsychotics against their will, often justified by claims about risk of violence.

Genes that influence the metabolism of alcohol also influence the risk of alcoholism, and may be indicated by a family history of alcoholism.

Severe childhood trauma is also associated with a general increase in the risk of drug dependency.

A good illustration of the risk of DLC arbitrage is the position in Royal Dutch Shell — which had a DLC structure until 2005 — by the hedge fund Long-Term Capital Management ( LTCM, see also the discussion below ).

The trade-credit must not only be known and guaranteed, but also be valued in an amount the media and advertising could have been purchased for had the " client " bought it themselves ( contract to eliminate ambiguity and risk ).

It also increased maneuverability and therefore reduced the risk of coming under raking fire.

To ensure that in the smoke and confusion of a night battle his ships would not accidentally open fire on one another, Nelson ordered that each ship prepare four horizontal lights at the head of their mizenmast and also to hoist an illuminated White Ensign, which was different enough from the French tricolour that it would not be mistaken in poor visibility, reducing the risk that British ships might fire on one another in the darkness.

Tolerance can develop to their effects and there is also a risk of dependence, and upon discontinuation a withdrawal syndrome may occur.

In these groups, impulse control problems are perhaps the most important risk factor for disinhibition ; learning disabilities and neurological disorders are also significant risks.

The grid separates the flame into an array of smaller flames with a common external envelope, and also prevents flashback to the bottom of the tube, which is a risk at high air-to-fuel ratios and limits the maximum rate of air intake in a conventional Bunsen burner.

Central banks usually also have supervisory powers, intended to prevent bank runs and to reduce the risk that commercial banks and other financial institutions engage in reckless or fraudulent behavior.

For this reason, clowning is often considered an important part of training as a physical performance discipline, partly because tricky subject matter can be dealt with, but also because it requires a high level of risk and play in the performer.

of time is also believed to be a risk factor.

It may also be viewed as part of a continuing process begun by the Instrumentality, encompassing the whole cycle, where mankind is constantly at risk of falling back into bad old ways.

The increased use of antineoplastic agents in veterinary oncology also puts these workers at risk for exposure to these drugs.