Aachen has a large number of spin-offs from the university's IT-technology department and is a major centre of IT development in Germany.

The second Abbasid caliph, Al Mansur ( 754 – 775 ) founded the city of Baghdad to act as a centre of learning, and included in its design a library-translation centre known as Bayt al-Hikma ‘ Storehouse of Wisdom ’, which continued to receive development from his heirs and was to provide a major impetus for Arabic-Persian translations of Hellenistic astrological texts.

The city started to play a regional role as a major urban centre on the fringes of the newly founded Frankish Duchy of Vasconia.

Besieged several times during its history, Barcelona has a rich cultural heritage and is today an important cultural centre and a major tourist destination.

Indeed, it is a major cultural and economic centre in southwestern Europe ( Iberian Peninsula ), 26th in the world ( after Moscow, before Dubai ) and a growing financial centre ( Diagonal Mar and Gran Via ).

Located in northwest Switzerland on the river Rhine, Basel functions as a major industrial centre for the chemical and pharmaceutical industry.

Copenhagen is a major regional centre of culture, business, media, and science, as indicated by several international surveys and rankings ( see International rankings below ).

Through the reputation of its venerable founder and its position as a major European centre of learning, Columba's Iona became a place of pilgrimage.

During the 1940s and 1950s, Casablanca was a major centre of anti-French rioting.

Dublin Castle, which became the centre of Norman power in Ireland, was founded in 1204 as a major defensive work on the orders of King John of England.

The city played no major role in the Industrial Revolution, but remained the centre of administration and a transport hub for most of the island.

The clearest symbol of the whole effort was the ambitious Canary Wharf project that constructed Britain's tallest building and established a second major financial centre in London.

Over the past 30 years, the population of the Docklands has more than doubled and the area has become both a major business centre and an increasingly desirable area to live.

Damascus was a major trading centre which abounded in wealth and was under normal circumstances a potential threat, but the rulers of Jerusalem had recently entered into a truce with the city, which they then forswore.

Fort William is a major tourist centre with Glen Coe just to the south, Aonach Mòr to the north and Glenfinnan to the west, on the Road to the Isles.

Florence is also an important city in Italian fashion, being ranked within the top fifty fashion capitals of the world ; furthermore, it is also a major national economic centre, being a tourist and industrial hub.

The German army celebrated the victory and demonstrated its might with a major military parade in the centre of Helsinki on 14 April 1918.

At that time Pergamon was a major cultural and intellectual centre, noted for its library ( Eumenes II ), second only to that in Alexandria,

Gosford is considered a major commercial centre of the Sydney Metropolitan Area, and has been designated as an important growth centre under the NSW Metropolitan Strategy.

Since German reunification in 1990, and the accession of some Central European and Baltic States into the European Union in 2004, the Port of Hamburg has restarted ambitions for regaining its position as the region's largest deep-sea port for container shipping and its major commercial and trading centre.

Tripolitania was a major exporter of olive oil ( produced there with the Centenaria farm system, protected by the Limes Tripolitanus ), as well as a centre for the gold and slaves conveyed to the coast by the Garamentes, while Cyrenaica remained an important source of wines, drugs, and horses.

The large number of coaching inns is, in turn, one reason why the City has so many pubs today ( another being that it was, and remains, a major centre for Christian pilgrimage ).

Examples are in public utilities, making military aircraft and accessories, or where the investment and risk for a proprietorship would be too great for a much needed project impossible to achieve by any means other than the corporate form, e.g. constructing major airports or dams.

But the fact remains that even the unconscious acceptance of himself as a man of destiny divinely protected must be censored in any man who evades the responsibility for his major decisions, and thus for imposing his will on the people.

Drifting through a third illness, apparently without any provision for the handling of a major national emergency other than a talk with the vice-president, Eisenhower revealed the singularly static quality of his thinking.

The pamphlets are about law, the corporation, forms of government, the idea of freedom, the defense of liberty, the various lethargies which overtake our major institutions, the gap between traditional social ideals and the working mechanisms that have been set in motion for their realization.

Carl has been married to Paula for fifty-three years, and he has not made a single major decision without careful consideration and thorough discussion with his wife.

Relieved of the major part of his responsibility for the safety of the ship, the pilot's oaths became fewer.

At the same time, a major proportion of these young men and women see religion as a means of personal adjustment, an anchor for family life, a source of emotional security.

What is wrong with advertising is not only that it is an `` outrage, an assault on people's mental privacy '' or that it is a major cause for a wasteful economy of abundance or that it contains a coercive tendency ( which is closer to the point ).

Naturally, the statewide races will provide the major test for the expanding council.

A reporter restricted to the competing propaganda statements of both sides in a major labor dispute, for instance, is unable to tell his readers half of what he knows about the causes of the dispute.

In fact, one of the major reasons for the failure of the ill-starred expedition appears to have been a lack of full information on the extent to which Cuba has been getting this Russian military equipment.

The cost of developing a major weapon system is now so enormous that the greatest care must be exercised in selecting new systems for development, in determining the most satisfactory rate of development, and in deciding the proper time at which either to place a system into production or to abandon it.

Along with J. R. Brown's other major developments, the universal grinding machine was profoundly influential in setting the course of Brown & Sharpe for many years to come.

In addition to its major effort on fuel cells, Patterson Moos Research Division is continuing to carry on research in other fields, both under contract for the Defense Department, other government agencies and for our own account.

In addition to the three major original equipment segments of the electronics business, the steady growth in the market for replacement parts continues year by year.

For this first development the supplier signing the lease is a major oil company but in turn the deal is being transferred for operation to its local fueloil distributor.

The major gets the assured gallonage for the life of the lease and the distributor apparently can do well because delivery cost is low.

Currently, there are some 6000 companies in the field, ranging from small firms with a handful of employees to major concerns having complete facilities for production of metal, electrical, and plastic components.

According to one major producer, materials for a typical plastic sign are approximately 25% less costly than for a comparable neon unit.

A major portion of the credit should also go to flautist Haumd for his rendering of the almost impossible `` Indianapolis '' movement in the Baslot.

In addition, many of the hard-surface cleaners used for walls and woodwork had their genesis in trisodium orthophosphate, which is still the major ingredient of a number of such products.