Recent studies imply that methylphenidate may also act on serotonergic systems ; this may be important in explaining the paradoxical calming effect of stimulants on ADHD patients.

The paradoxical effect is that, the harder policing agencies work to produce security, the greater are feelings of insecurity.

While dealing with serious topics in what are now known as anthropology, sociology and psychology, he introduced a satirical approach, " based on the premise that, however serious the subject under review, it could be made more interesting and thus achieve greater effect, if only one leavened the lump of solemnity by the insertion of a few amusing anecdotes or by the throwing out of some witty or paradoxical observations.

The paradoxical effect of these warnings has been to encourage, rather than discourage, visitors.

Much discussion has occurred regarding the optimum capital gains tax rate, with some advocates calling for tax cuts in the belief that a lower rate ( e. g., under 25 %) will provide an incentive to investors to sell old stocks and invest in new stocks — which supply siders maintain encourages the creation of new jobs, reduces unemployment, and has the paradoxical effect of increasing tax revenues more or less immediately, an idea first proposed by economist Arthur Laffer while an advisor to Ronald Reagan ( See Laffer curve ).

While dealing with serious topics in what are now known as anthropology, sociology and psychology, he introduced a satirical approach, " based on the premise that, however serious the subject under review, it could be made more interesting and thus achieve greater effect, if only one leavened the lump of solemnity by the insertion of a few amusing anecdotes or by the throwing out of some witty or paradoxical observations.

His defenders also argued Rousseau is one of the great prose stylists and because of his penchant for the paradoxical effect obtained by stating something strongly and then going on to qualify or negate it, it is easy to misrepresent his ideas by taking them out of context.

A paradoxical reaction or paradoxical effect is an effect of medical treatment, usually a drug, opposite to the effect which would normally be expected.

The paradoxical effect or Eagle phenomenon ( named after H. Eagle who first described it ) refers to an observation of an increase in survivors, seen when testing the activity of an antimicrobial agent.

** Tianeptine — paradoxical antidepressant ( considered to be a selective serotonin reuptake enhancer ( SSRE ) ( note that no widely known proof of direct SSRE action exists )), improves mood and reduces anxiety ; action on the NMDA and AMPA receptor, a hypothesized mechanism of action, based on tianeptine's effect of promoting stress-associated impaired neuroplasticity ; it enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D < sub > 2 </ sub > and D < sub > 3 </ sub > dopamine receptors, but this effect is modest and almost certainly indirect.

It is possible that this can occasionally lead to a paradoxical situation, where the enzymatic inhibition causes a decrease in the drug's effect: If the metabolism of drug A gives rise to product A < sub > 2 </ sub >, which actually produces the effect of the drug.

As in the previous case it is possible to find paradoxical situations where an active metabolite causes the drug ’ s effect.

While dealing with serious topics in what are now known as anthropology, sociology and psychology, he introduced a satirical approach, " based on the premise that, however serious the subject under review, it could be made more interesting and thus achieve greater effect, if only one leavened the lump of solemnity by the insertion of a few amusing anecdotes or by the throwing out of some witty or paradoxical observations.

The war would be a dark chapter in Argentine history, but would have the paradoxical effect of creating one of the most fortuitous circumstances in the history of any rock genre.

* Rebound effect ( paradoxical negative effect )

A paradoxical worsening of depression has been reported in some individuals in several studies, and reports of suicidal ideation and suicide as a adverse effect have been reported as a rare adverse effect of moclobemide.

In a paradoxical way, Kant supported in the same time enlightened despotism as a way of leading humanity towards its autonomy.

) Where the irony with which Reefer Madness was adopted as a midnight favorite had its roots in a countercultural sensibility, in the latter's place there is now the paradoxical element of nostalgia: the leading revivals currently on the circuit ironically include clearly non-cult films like John Hughes oeuvre — The Breakfast Club ( 1985 ), Pretty in Pink ( 1986 ), and Ferris Bueller's Day Off ( 1986 ), which were major studio productions and popular and financially successful during their original releases, and the teen adventure film The Goonies ( 1985 ).

Even his friend Antoine-Jacques Roustan felt impelled to write a polite rebuttal of the chapter on Civil Religion in the Social Contract, which implied that the concept of a Christian Republic was paradoxical since Christianity taught submission rather than participation in public affairs.

This was 1935, but in 1964 it was shown by John Bell ( see Bell inequality ) that-although Einstein was correct in identifying seemingly paradoxical implications of quantum mechanical nonlocality-these implications could be experimentally tested.

" Cohen therefore considers it paradoxical " that the rise of early modern science was due at least in part to developments in Christian thought — in particular, to certain aspects of Protestantism " ( a thesis first developed as what is now sometimes called the Merton thesis ).

More recently, sociologist and historian of science Steven Shapin opened his book, The Scientific Revolution, with the paradoxical statement: " There was no such thing as the Scientific Revolution, and this is a book about it.

) The reason for his restriction was that languages that contain their own truth predicate will contain paradoxical sentences like the Liar: This sentence is not true.

Historian Norman F. Cantor has made the paradoxical statement that he was " the most effective king in Anglo-Saxon history ", despite his not being Anglo-Saxon.

It was applied to issues such as cutting-plane, with the paradoxical examples of connected components.

This proved paradoxical, as Caine was to become notable for using a regional accent, rather than the Received Pronunciation hitherto considered proper for film actors.

His youthful imagination was unbridled, and his ideas ran easily into a kind of paradoxical subtlety, redolent of the divinity school.

Both helminthic therapy and fecal bacteriotherapy induce a characteristic Th2 white cell response in the diseased areas, which is somewhat paradoxical given that ulcerative colitis immunology was thought to classically involve Th2 overproduction.

Richard claimed that the flaw in the paradoxical construction was that the expression for the construction of the real number r does not actually unambiguously define a real number, because the statement refers to the construction of an infinite set of real numbers, of which r itself is a part.

It has been argued that Sombart's formulation of the concept was influenced by Eastern mysticism, specifically the image of the Hindu god Shiva, who is presented in the paradoxical aspect of simultaneous destroyer and creator.

On the tactical side, the battle was paradoxical.

By contrast, the origin in post-War Britain, while employing irony and parody, was more academic with a focus on the dynamic and paradoxical imagery of American popular culture as powerful, manipulative symbolic devices that were affecting whole patterns of life, while improving prosperity of a society.

In many mythologies, the lost mythical age was a Paradise, " a paradoxical state in which the contraries exist side by side without conflict, and the multiplications form aspects of a mysterious Unity ".

Sfumato is where there are no harsh outlines, and it is painted with full strokes that enhance color and light. The areas blend together Hence the term " Sfumato " was used by Michael J. Gelb on his book How to Think Like Leonardo da Vinci to describe one of da Vinci's mental abilities, namely the ability to hold three paradoxical ideas in one's mind without difficulty.

" A sceptical work that debunks a number of legends circulating at the time in a paradoxical and witty manner ; it displays the Baconian side of Browne — the side that was unafraid of what at the time was still called " the new learning ".

The study was based on the paradoxical observation that despite improved technology, productivity was falling, and that despite better pay and amenities, absenteeism was increasing.

In response, another physicist named Joseph Polchinski sent them a letter in which he argued that one could avoid questions of free will by considering a potentially paradoxical situation involving a billiard ball sent through a wormhole which sends it back in time.

The possibility remained that, with respect to our actual configuration of knowledge, which is very different from Good's example, Nicod's criterion might still be true and so we could still reach the paradoxical conclusion.

Funny animals have been a staple of comics, and while they have traditionally been thought of as being for children, the underground had long made use of them for adult stories, notably in Robert Crumb's work ( such as Fritz the Cat ) which showed that the genre could " open up the way to a paradoxical narrative realism " that Maus would exploit.

In 1990, commenting on the Novikov self-consistency principle ( in relation to sending objects or people through a traversable wormhole into the past, and the time paradoxes that could result ), Polchinski raised a potentially paradoxical situation involving a billiard ball sent through a wormhole which sends it back in time.

Initially it was thought that agonists could be used as potent and prolonged stimulators of pituitary gonadotropin release, but it was soon recognized that agonists, after their initial stimulating action – termed a “ flare ” effect-eventually caused a paradoxical and sustained drop in gonadotropin secretion.

However, this also resulted in a paradoxical future in which he never existed ; thus, he has no home to which he could ever conceivably return.