Although single genes have little effect on complex traits and interact heavily both between themselves and with the external factors, research is underway to unravel possible molecular mechanisms underlying anxiety and comorbid conditions.

Although the hardware is limited to four separate sound channels, software such as OctaMED uses software mixing to allow eight or more virtual channels, and it was possible for software to mix two hardware channels to achieve a single 14-bit resolution channel by playing with the volumes of the channels in such a way that one of the source channels contributes the most significant bits and the other the least.

Although " Takes A Little Time " was a moderate hit single, the album failed to sell like the previous two albums, which had both gone multi-platinum.

Although BR was a single entity, it was divided into six ( later five ) regional authorities in accordance with the existing areas of operation.

Although his success lasted only a year and a half before his death in an airplane crash, Holly is described by critic Bruce Eder as " the single most influential creative force in early rock and roll.

Although there is no strong evidence for any single theory, many independent theories exist, some blaming storms, some capsizing, and some suggesting that wartime enemy activity was to blame for the loss.

" Although based on a simplistic analysis of internal strife in Greece and Turkey, it became the single dominating influence over U. S. policy until at least the Vietnam War.

Although some say Judaism is noncreedal in nature, others say it recognizes a single creed, the Shema Yisrael, which begins: " Hear, O Israel: the LORD our God, the LORD is one.

Although the two parts are now normally published as a single work, Don Quixote, Part Two was a sequel published ten years after the original novel.

Although bacteriophages were first described in 1927, it was only in 1959 that Sinshemer working with phage Phi X 174 showed that they could possess single stranded DNA genomes.

Although the track was edited out of the final cut, it would later be re-recorded and released as " Safe " on the B-side of Bowie's 2002 single " Everyone Says ' Hi '".

Although the single sold poorly, the popularity of Jones's appearance on the show resulted in " Girl " becoming his best remembered solo hit, even though it was not included in the album.

Although many of the results in Elements originated with earlier mathematicians, one of Euclid's accomplishments was to present them in a single, logically coherent framework, making it easy to use and easy to reference, including a system of rigorous mathematical proofs that remains the basis of mathematics 23 centuries later.

Although it never uses the term, The Church of Jesus Christ of Latter-day Saints ( The Mormon Church ) is episcopal, rather than presbyterian or congregational, in the sense that it has a strict hierarchy of leadership from the local bishop up to a single prophet / president, believed to be personally authorized and guided by Jesus Christ.

Although there are important differences between them, all of them were materialists who believed that the world was made up of a single substance, matter, the motions and properties of which could be used to explain all phenomena.

Although its file format also allows for multiple such streams to be concatenated ( zipped files are simply decompressed concatenated as if they were originally one file ), gzip is normally used to compress just single files.

Although turret presses operate much like single stage presses, they eliminate much of the setup time required in positioning individual dies correctly.

" Although it was a single sentence in a 461-page book, reviewers focused on it.

Although the school was a single institution, it was divided into two parts: a grammar school called the collège or schola privata and an advanced school called the académie or schola publica.

Although he is often characterized as an " architect " exclusively, as James Beck has observed, " to single out one of Leon Battista's ' fields ' over others as somehow functionally independent and self-sufficient is of no help at all to any effort to characterize Alberti's extensive explorations in the fine arts.

Although they reign under constitutions, the monarchs of Brunei, Oman, Qatar, Saudi Arabia and Swaziland appear to continue to exercise more political influence than any other single source of authority in their nations, either by constitutional mandate or by tradition.

Although the term " metallic bond " is often used in contrast to the term " covalent bond ", it is preferable to use the term metallic bonding, because this type of bonding is collective in nature and a single " metallic bond " does not exist.

Although four songs were released as singles to promote the album ( lead single " Everything I Need ", " Man With Two Hearts ", " Maria ", and " Hard Luck Story "), only the first song charted in the US, and that only at No. 47.

Although they do share commonalities, contemporary Pagan religious movements are diverse and no single set of beliefs, practices, or texts are shared by them all.

Although it was dark as usual I could see that the hall had only recently contained a great many people.

Although New Orleans was not to learn of it for a spell, she also was a sadist, a nymphomaniac and unobtrusively mad -- the perpetrator of some of the worst crimes against humanity ever committed on American soil.

Although Faulkner was the heir in his own family to this tradition, he did not have Stark Young's inclination to romanticize and sentimentalize the planter society.

Although his tender nights were not the ones I dreamed of, nor was it for yachts, sports cars, tall drinks, and swimming pools, nor yet for money or what money buys that I burned, I too was burning and watching myself burn.

Although after much trouble he did manage to get it back, he discovered there was no trade to be had.

Although he did not attend any celebrated schools or universities, he was a master of Greek and Hebrew and could read the Bible in the original.

Although the fort was evacuated in the face of the force of Cornwallis, Morgan and his men did have a chance to take another swing at the redcoats.

Although because of the important achievements of nineteenth century scholars in the field of textual criticism the advance is not so striking as it was in the case of archaeology and place-names, the editorial principles laid down by Stevenson in his great edition of Asser and in his Crawford Charters were a distinct improvement upon those of his predecessors and remain unimproved upon today.

Although Mr. Brown was not himself its inventor ( it was a French idea ), it is typical that his intuition first conceived the importance of mass producing this basic tool for general use.

Although it was a mere fragment of the victim's remains, it was enough.

Although there were only four fluids tested, it was apparent that there were two distinct types.

Although the tape was run for over 1 hr., a steady state was not reached, and it was concluded that the reason for this was that the back pressure of the manometer was built up from the material fed from between the blocks and this was available at a very slow rate.

-- Although there was some variation in results which must be attributed either to trace impurities or to variation in wall effects, the photochemical exchange in the gas phase was sufficiently reproducible so that it seemed meaningful to compare the reaction rates in different series of reaction tubes for the purpose of obtaining information on the effect of chlorine concentration and of carbon tetrachloride concentration on the reaction rate.

Although the Taylor Scale was designed as a group testing device, in this study it was individually administered by psychologically trained workers who established rapport and assisted the children in reading the items.

Although the primary mathematical properties of the middle number at the center of the Lo Shu, and the interrelation of all the other numbers to it, might seem enough to account for the deep fascination which the Lo Shu held for the Old Chinese philosophers, this was actually only a beginning of wonders.

Although Dirac did not himself use the term antimatter, its use follows on naturally enough from antielectrons, antiprotons, etc.

Although he was aware that the Bastarnae were hardly likely to achieve the same success as Hannibal some 40 years earlier, and would most likely end up cut to pieces by the Romans, Philip hoped that the Romans would be distracted long enough to allow him to reoccupy his former possessions in Greece.

Although he now had enough ships to challenge the French fleet, Nelson suffered two great disadvantages: he had no intelligence regarding the destination of the French, and no frigates to scout ahead of his force.

Although Japan eventually recognized the People's Republic in 1972, shortly after Kakuei Tanaka succeeded Sato as Prime Minister of Japan, the memory of this relationship was strong enough to be reported by The New York Times ( April 15, 1978 ) as a significant factor inhibiting trade between Japan and the mainland.

Although perestroika was considered bold in the context of Soviet history, Gorbachev's attempts at economic reform were not radical enough to restart the country's chronically sluggish economy in the late 1980s.

Although the words written in it are close enough to Italian and Latin for the non-Corsican speaker with a language background to follow, the pronunciation of those letters in English, French or Italian is not a guide to the pronunciation of Corsican, which follows complex rules.

Although he lacks superhuman strength, Captain America is one of the few mortal beings who has been deemed worthy enough to wield Thor's hammer.

Although little information survives of the battles fought, enough early victories were apparently achieved for Domitian to be back in Rome by the end of 83, where he celebrated an elaborate triumph and conferred upon himself the title of Germanicus.

" Although not expressed as strongly, Glyn Jones believed that he and Thomas ' friendship cooled in the later years as he had not ' rejected enough ' of the elements that Thomas disliked – " Welsh nationalism and a sort of hill farm morality ".

Although humans exist and operate within ecosystems, their cumulative effects are large enough to influence external factors like climate.

Although humans exist and operate within ecosystems, their cumulative effects are large enough to influence external factors like climate.

Although not as popular as other programming systems, Forth has enough support to keep several language vendors and contractors in business.

Although the statement of the theory in terms of graphs may imply perturbation theory, use of graphical methods in the many-body problem shows that this formalism is flexible enough to deal with phenomena of nonperturbative characters ...

Although he considered himself close to, but not a member of, al-Qa ' ida, he knew enough about the senior members, organization and operations to claim to be a member.

Although animal products & numbers of livestock are increasing, this isn't enough for local requirements for a growing population.

Although it says and or by the law of the land, this in no manner can be interpreted as if it were enough to have a positive law, made by the king, to be able to proceed legally against a citizen.

Although winters are generally cold and clear, there are occasional blizzards that do not deposit much snow but cover the grasses with enough snow and ice to make grazing impossible, killing off tens of thousands of sheep or cattle.

Although the scale statement is nominal it is usually accurate enough for all but the most precise of measurements.

Although this made control crude the models were large and robust enough that grabbing the controls was practical.

Although he is romantically terrified of her at first, he later summons up enough courage to ask her out and they fall in love.

Although those ‘ cold ’ emotions might be enough to show effects, they are qualitatively different from the ‘ hot ’ emotions often experienced during negotiations.

Although himself a German nationalist, Spengler viewed the Nazis as too narrowly German, and not occidental enough to lead the fight against other peoples.