Although single genes have little effect on complex traits and interact heavily both between themselves and with the external factors, research is underway to unravel possible molecular mechanisms underlying anxiety and comorbid conditions.

Although Cambria Iron and Steel's facilities were heavily damaged by the flood, they returned to full production within a year .. After the flood, Carnegie built Johnstown a new library to replace the one built by Cambria's chief legal counsel Cyrus Elder, which was destroyed in the flood.

Although both polysaccharide classes share the same galactose-based backbone, agaropectin is heavily modified with acidic side-groups, such as sulfate and pyruvate.

Although Carmilla is a lesser known and far shorter Gothic vampire story than the generally-considered master work of that genre, Dracula, the latter is heavily influenced by Le Fanu's short story.

Although the majority of WADs contain one or several custom levels mostly in the style of the original game, others implement new monsters and other resources, and heavily alter the gameplay ; several popular movies, television series, other video games and other brands from popular culture have been turned into Doom WADs by fans ( without authorization ), including Aliens, Star Wars, The X-Files, The Simpsons, South Park, Sailor Moon, Dragon Ball Z, Red Faction, The Thing, Pokémon and Batman.

Although Jews were heavily taxed, no contemporary authors mention trials or executions based on religious offenses other than those within the Roman religion.

Although filmed, and covered heavily by the press, pressure from Disney ( which owns parts of the concept ) prevented further distribution.

Although heavily outnumbered by Portuguese troops ( approximately 30, 000 Portuguese to some 10, 000 guerrillas ), the PAIGe had the great advantage of safe havens over the border in Senegal and Guinea, both recently independent of French rule.

Although the First Battle of Independence in August 1862 resulted in a Confederate victory, the Southerners were unable to follow up their win in any significant fashion, as the City of Kansas was occupied by Union troops and proved too heavily fortified for them to assault.

Although she lived before left communism became a distinct tendency, Rosa Luxemburg has heavily influenced most left communists, both politically and theoretically.

Although the membership of the Assembly was heavily weighted towards the presbyterians, Oliver Cromwell was a Congregationalist separatist who imposed his views.

Although encountering the flaw was extremely rare in practice ( Byte magazine estimated that 1 in 9 billion floating point divides with random parameters would produce inaccurate results ),< ref > both the flaw and Intel's initial handling of the matter were heavily criticized.

Although Will Smith and Idris Elba were heavily rumored to be up for the title role, Jamie Foxx has since been confirmed to play Django.

Although there is little doubt that the writers of the Second Amendment were heavily influenced by the English Bill of Rights, it is a matter of interpretation as to whether they were intent on preserving the power to regulate arms to the states over the federal government ( as the English Parliament had reserved for itself against the monarch ) or whether it was intent on creating a new right akin to the right of others written into the Constitution ( as the Supreme Court recently decided ).

Although he never graduated, during his time at the university he was heavily involved in the Virginia Glee Club and the Jefferson Literary and Debating Society, serving as the society's president.

Although Yeats ' early works drew heavily on Shelley, Edmund Spenser, and on the diction and colouring of pre-Raphaelite verse, he soon turned to Irish mythology and folklore and the writings of William Blake.

Although winning the Democratic primary is normally tantamount to election in heavily Democratic Chicago, after his primary victory Washington found that his Republican opponent, former state legislator Bernard Epton ( earlier considered a nominal stand-in ), was supported by many white Democrats and ward organizations, including the chairman of the Cook County Democratic Party, Alderman Edward " Fast Eddie " Vrdolyak.

Although fantasy, particularly the sub-genre of fairytale fantasy, draws heavily on fairy tale motifs, the genres are now regarded as distinct.

Although it draws heavily on symbiosis ideas first put forward by mid-19th century scientists and by Merezhkovsky ( 1905 ) and Ivan Wallin ( 1920 ) in the early-20th century, Margulis's endosymbiotic theory formulation is the first to rely on direct microbiological observations ( as opposed to paleontological or zoological observations which were previously the norm for new works in evolutionary biology ).

Although the report was embarrassing to the Reagan administration, who was heavily aiding the right-wing junta at the time, skeletons unearthed a decade later confirmed the original story's veracity.

Although heavily outnumbered, the Greek Allies were persuaded by the Athenian general Themistocles to bring the Persian fleet to battle again, in the hope that a victory would prevent naval operations against the Peloponessus.

Although he is something of a hero in his native Scandinavia, reliable accounts of his life are very sketchy and heavily based on ancient Viking sagas.

Although inexperienced in sea battles, the Romans, led by consul Gaius Duilius Nepos, heavily defeat the Carthaginian fleet, mainly due to the innovative use of land tactics in naval warfare ( including the use of the grappling irons and the corvus boarding bridge ).

Although the Republicans heavily outnumbered their opponents and managed to push 12 kilometres inland, superior Nationalist air power mainly provided by Fascist Italy forced the Republicans to retreat and to leave the island completely by September 12.

Although Wiggum can often antagonize others as well, it is heavily implied that it is not out of malice but merely because he is doing his job or because he is ignorant of the situation.

Although nearly 40 percent of Panama is still wooded, deforestation is a continuing threat to the rain-drenched woodlands.

Although the area is generally flat and open with less than a variation in altitude, Horrocks, commander of XXX Corps recalled that " The country was wooded and rather marshy which made any outflanking operation impossible.

Although Varna receives about two thirds of the average rainfall for Bulgaria, abundant groundwater keeps its wooded hills lush throughout summer.

Although 18th century documents report that it was once densely wooded, humans and the animals they brought have destroyed the trees on the island, which is now largely grassland.

Although the town itself is heavily industrial it is surrounded by fertile farmland and wooded areas.

Although the royal forest of Selwood no longer exists, the nearby countryside is still richly wooded, for example on the Longleat, Maiden Bradley and Stourhead estates.

Although they usually only breed in forests, Hermit Thrushes will sometimes winter in parks and wooded suburban neighbourhoods.

Although the land is mostly flat and about half of the area is used for grazing cattle, and wildlife is threatened by introduced species and weeds, the relatively undisturbed eucalyptus wooded savannahs, tropical rainforests and other types of habitat are now recognized for their global environmental significance.

" Although it was widely reported the Air France plane landed in a heavily wooded area, the area is in fact is fairly wide open, due to airport maintenance of both sides of the ravine.

Although the area was in part heavily wooded, many Anglo Saxon finds have been made indicating thriving communities around Brockley Hill and Harrow Weald Common.

Although unused the building still exists, in wooded land to the west of the town, on the site of the former Worsley New Hall.

Although this second royal residence was to be built in what were then outlying areas of Madrid, it was actually not far from the existing Alcázar or fortress residence, and the location in a cool, wooded area proved to be ideal.

Although it was dark as usual I could see that the hall had only recently contained a great many people.

Although Sam Rayburn affects a gruff exterior in many instances, nevertheless he is fundamentally a man of warm heart and gentle disposition.

Although there are many sound reasons for adopting uniform and coordinated fiscal years in Rhode Island, there are also certain difficulties encountered.

Although science has given us more effective materials, preparations from anise, castorbean, colchicum, nux vomica, mustard, fennel, and stramonium are familiar to many for the relief of human ailments.

Although economic and personal circumstances vary widely among those now choosing apartments, Leo J. Pantas, vice president of a hardware manufacturing company, pointed out recently that many apartment seekers seem to have one characteristic in common: a desire for greater convenience and freedom from the problems involved in maintaining a house.

Although the Administration's program cut crop acreage to the lowest point since 1934, farmers, with the help of extra fertilizer and good weather, are getting such high yields per acre that many are being forced to buy new harvesting machines.

Although modern scholars have expressed surprise that `` the simple magic square of three '', a mere `` mathematical puzzle '', was able to exert a considerable influence on the minds and imaginations of the cultured Chinese for so many centuries, they could have found most of the answers right within the square itself.

Although in many frog species, females are larger than males, this is not the case in most species where males are actively involved in territorial defence.

Although it had at first been somewhat established in many colonies, in 1861 it was ruled that, except where specifically established, the Church of England had just the same legal position as any other church.

Although ataxia is not present with all cerebellar lesions, many conditions affecting the cerebellum do produce ataxia.

Although Doubleday achieved minor fame as a competent combat general with experience in many important Civil War battles, he is more widely remembered as the supposed inventor of the game of baseball, in Elihu Phinney's cow pasture in Cooperstown, New York, in 1839.

Although an explanation for the phenomenon was not provided until 1919, duralumin was one of the first " age hardening " alloys to be used, and was soon followed by many others.

Although Romanticism and Neoclassicism were philosophically opposed, they were the dominant European styles for generations, and many artists were affected to a greater or lesser degree by both.

Although not as accurate by themselves as STOs, combinations of many Gaussians can attain the accuracy of hydrogen-like orbitals.

Although he was not an innovator, he would not follow the absolute letter of the law ; rather he was driven by concerns over humanity and equality, and introduced into Roman law many important new principles based upon this notion.

Although the authenticity of this epigram was accepted for many centuries, it was probably not composed for Agathon the tragedian, nor was it composed by Plato.

Although metics had no direct political influence many were wealthy business owners who could, and sometimes did, influence policy by not allowing their citizen employees time off to attend the assembly, as well as having the simple expedient of wealth.

Although many other chemists have repeated this advice, IUPAC and most chemistry texts still favour the usage of allotrope and allotropy for elements only.

" Although heterogeneous, the major CAM systems have many common characteristics, including a focus on individualizing treatments, treating the whole person, promoting self-care and self-healing, and recognizing the spiritual nature of each individual.

Although game reports and social reactions are common parts of many A & E contributions, it has also, over the years, become a testing ground for new ideas on the development of the RPG as a genre and an art form.

Although still actively involved in running his many businesses, Carnegie had become a regular contributor to numerous magazines, most notably the Nineteenth Century, under the editorship of James Knowles, and the influential North American Review, led by editor Lloyd Bryce.

Although there are many other acropoleis in Greece, the significance of the Acropolis of Athens is such that it is commonly known as " The Acropolis " without qualification.

Although the Falcons selected many good players in those drafts, they still were not able to win right away.

Although most cultural systems of astrology share common roots in ancient philosophies that influenced each other, many have unique methodologies which differ from those developed in the West.

Although modern analytical chemistry is dominated by sophisticated instrumentation, the roots of analytical chemistry and some of the principles used in modern instruments are from traditional techniques many of which are still used today.