Although histone modifications occur throughout the entire sequence, the unstructured N-termini of histones ( called histone tails ) are particularly highly modified.

Although classified as eukaryotes, the dinoflagellate nuclei are not characteristically eukaryotic, as they lack histones, nucleosomes and maintain continually condensed chromosomes during mitosis.

Although he questions the extent and nature of the alleged revival of religion and the alleged increase in conformity, and thinks that `` hedonistic '' present-time orientation does not have the meaning usually attributed to it, he does conclude that Americans increasingly enjoy leisure without guilt, do not stress achievement so much as formerly, are more accepting of group harmony as a goal, more tolerant of diversity and aware of other cultures.

Although the false glamour surrounding bourbon or other whisky commercials is possibly no more fatuous than the pseudo-sophistication with which TV soft-drinks are downed or toothpaste applied, there is a sad difference between enticing a viewer into sipping Oopsie-Cola and gulling him into downing bourbon.

Although the United States and the U.S.S.R. have been arguing whether there shall be four, five or six top assistants, the most important element in the situation is not the number of deputies but the manner in which these deputies are to do their work.

Although today's trucks are as fast as passenger cars, a truck driver has to be a sensible person and guard against hogging the road.

Although they are forbidden to sit with the customers, the dancers are sometimes proffered drinks, and most of them can bolt one down in mid-shimmy.

Although there are many sound reasons for adopting uniform and coordinated fiscal years in Rhode Island, there are also certain difficulties encountered.

Although the site may not contain the features themselves, there are often opportunities to include them as additional interest to the site.

Although the play does show a certain structural amateurishness ( there are eleven acts varying in length from twenty-five seconds to an hour and a half ), the statement it makes concerning the ceaseless yearning and searching of youth is profound and worthy of our attention.

Although there is no question but that the process of washing fabrics involves a number of phenomena which are related together in an extremely complicated way and that these phenomena and their interrelations are not well understood at the present, this section attempts to present briefly an up-to-date picture of the physical chemistry of washing either fabrics or hard surfaces.

Although the standard deviation values on which spread of the lines is based are relatively larger for those centers which begin to ossify early ( Table 1 ), there are considerable differences in this value between centers having the closely timed Onsets.

Although in both emotions sympathetic symptoms are present, different autonomic-somatic patterns underlie aggression and anxiety, respectively, as indicated by the rate of the excretion of the catecholamines, the state of the muscle tone, and the Mecholyl test.

Although we are still far from a complete understanding of these problems, as a first approximation, it is suggested that alterations in the hypothalamic balance with consequent changes in the hypothalamic-cortical discharges account for major changes in behavior seen in various moods and states of emotions in man and beast under physiological circumstances, in experimental and clinical neurosis, and as the result of psychopharmacological agents.

Although the inner functions of religion are not of direct significance in social organization, they have important indirect consequences.

Although the Brandywine population is still predominantly rural, `` there are indications of a consistent and a statistically significant trend away from the older and relatively isolated rural communities.

Although science has given us more effective materials, preparations from anise, castorbean, colchicum, nux vomica, mustard, fennel, and stramonium are familiar to many for the relief of human ailments.

Although the Administration's program cut crop acreage to the lowest point since 1934, farmers, with the help of extra fertilizer and good weather, are getting such high yields per acre that many are being forced to buy new harvesting machines.

Although progress has been made in America's system of libraries it still falls short of what is required if we are to maintain the standards that are needed for an informed America.

Although the theological forms of the past continue to exist in a way they do not in a more secularized situation, the striking thing is the rapidity with which they are being reduced to a marginal existence.

Although there are landscapes in the show ( one of the strongest is a vista of `` Gloucester Harbor '' in 1915 ), the human element was the compelling factor in Sloan's art.

Although Finnish wages and standard of living could not compete with wealthy Sweden until the 1970s, the Finnish economy rose remarkably from the ashes of World War II, resulting in the buildup of another Nordic-style welfare state.

Although the festival was remarkably peaceful given the number of people and the conditions involved, there were two recorded fatalities: one from what was believed to be a heroin overdose and another caused in an accident when a tractor ran over an attendee sleeping in a nearby hayfield.

Although he has been widely regarded as a dilettante or amateur, his scientific research was of remarkably high quality.

Although at the same latitude as Montreal in Canada or the Kuril islands in Russia, the area is quite mild throughout the year due to the influence of the Gulf Stream waters, and insolation is remarkably high, though far below the French Riviera on the Mediterranean Southern coast of France.

Although it encountered some maintenance difficulties, the F-100D proved remarkably adaptable to rough-field operations in the tropical heat and rain of Southeast Asia.

Although it is often dismissed as inaccurate, it is hard to pinpoint a passage where he is categorically in error ... his account of events has stood up remarkably well ... His interpretation of the Glorious Revolution also remains the essential starting point for any discussion of that episode ... What has not survived, or has become subdued, is Macaulay's confident belief in progress.

Although it was not strictly a folk song, " I'll Never Find Another You " was heavily influenced by Peter, Paul and Mary and featured a cyclical, 12-string guitar part that sounded remarkably similar to the guitar style that Jim McGuinn of The Byrds would popularize later that same year.

Although a date of 600 BC would put it well outside of the dates traditionally ascribed to Tullus Hostilius ' reign, this is hardly a problem ; the absurdly long reigns of the Roman kings have never been taken seriously by scholars ( with an average length of 34 years per king, the traditional chronology would be without historical parallel-even the remarkably stable and healthy English monarchy has an average reign of only 21 years ).

Although these side effects disappear quickly and remarkably when the medication is stopped, tardive, or late-persisting akathisia may go on long after the offending drug is discontinued, sometimes for a period of years — unlike the related tardive dyskinesia, which can be permanent.

Although critics have contended that the quality of its contents declined after Beardsley left and that The Yellow Book became a vehicle for promoting the work of Lane's authors, a remarkably high standard in both art and literature was maintained until the periodical ceased publication in the spring of 1897.

Although Foxe had written Norfolk " a remarkably frank letter " about the injudiciousness of his course, after Norfolk's condemnation, he and Alexander Nowell ministered to the prisoner until his execution, which Foxe attended, on 2 June 1572.

Although the public image of Ballymun has changed somewhat since the beginning of the Ballymun regeneration project in 1997, continuing social problems in Ballymun ensure it remains a remarkably different world to, for example, neighbouring Glasnevin.

Although coccoliths are remarkably elaborate structures whose formation is a complex product of cellular processes, their function is unclear.

Although most speakers are not exposed to these formations until after childhood, they can form new examples readily once introduced to the process, and their judgments of which formations are acceptable are remarkably consistent.

Although an understanding of reproduction and modern medicine is widespread in Trobriand Society, their traditional beliefs have been remarkably resilient.

Although it had been remarkably well-run for most of its life as a state-owned company, by the 1980s VASP was being plagued by inefficiency, losses covered by state capital injections, and a bloated payroll for political reasons.

Although Dawson's repertoire embraced a great deal of now dated popular songs and light music, he possessed a remarkably fluent and technically adroit vocal technique which enabled him to excel in highly demanding classical pieces.

Although at the same latitude as Montreal in Canada and the Kuril islands in Russia, the area is quite warm throughout the year, due to the influence of the Gulf Stream waters, and the number of sunny days per year is remarkably high, on a par with the French Riviera on the Mediterranean coast of France.

Although steam-pasteurization is remarkably complex, it has the advantages of inhibiting the growth of bacteria that facilitate the formation of tobacco-specific nitrosamines, while preserving the desired texture and mouthfeel of the snus.

Although Warner's early publications herald Craig's potion as a revelation, references to Craig soon disappeared from Warner's advertising, and ultimately the two ended up in court when Craig attempted to reenter the patent medicine business with a cure remarkably similar to the one he had sold to Warner.

Although it is disputed among historians as to whether King Charles did this in the hope that Baldwin would be killed in the ensuing battles with the Vikings, Baldwin managed the situation remarkably well.

Although not reclining, the front seats were remarkably versatile and could be easily adjusted for height and rake.

Although the changes originated in the Rootes styling department, they reinforced the link to the Loewy-designed Studebakers ; the Series II looked remarkably like a shortened Studebaker Golden Hawk.

Although the presence and strength of any given effect depends on the Wnt ligand, cell type, and organism, some components of the signaling pathway are remarkably conserved in a wide variety of organisms, from Caenorhabditis elegans to humans.