Although oxidation reactions are crucial for life, they can also be damaging ; plants and animals maintain complex systems of multiple types of antioxidants, such as glutathione, vitamin C, and vitamin E as well as enzymes such as catalase, superoxide dismutase and various peroxidases.

Although they did not know the reason at the time, Admiral Edward Vernon's sailors were healthier than the rest of the navy, due to the daily doses of vitamin C the sailors received.

Although these roles in assisting enzyme-substrate reactions are vitamins ' best-known function, the other vitamin functions are equally important.

Although allergic reaction from supplementation is possible, no known toxicity is associated with high doses of the phylloquinone ( vitamin K < sub > 1 </ sub >) or menaquinone ( vitamin K < sub > 2 </ sub >) forms of vitamin K, so no tolerable upper intake level ( UL ) has been set.

Although the two are identical in their vitamin activity, nicotinamide does not have the same pharmacological effects ( lipid modifying effects ) as niacin.

Although the vitamin A was not identified until the 20th century, written observations of conditions created by deficiency of this nutrient appeared much earlier in history.

Although this source of vitamins, in general, provides only a small part of the daily requirement, it makes a significant contribution when dietary vitamin intake is low.

Although it has many additional functions, thioredoxin reductase restores vitamin C and E as well as a number of other important antioxidant molecules back into their reduced forms, enabling them to counteract oxidative damage within body cells.

Although they did not know the reason at the time, Admiral Edward Vernon's sailors were healthier than the rest of the navy, due to the daily doses of vitamin C that prevented disease ( mainly scurvy ).

Although initial treatment of the disease usually involves injections of B < sub > 12 </ sub > to rapidly replace body stores, a number of studies have shown long-term vitamin replacement treatment may be maintained with high-dose oral B < sub > 12 </ sub > supplements, since sufficient B < sub > 12 </ sub > is absorbed from these by a normal intestine, even without any intrinsic factor.

Although subsequent trials and appeals from 1965 to 1973 concluded some of the FTC demands exceeded its authority, Geritol was already well known and continued to be the largest American company selling iron and B vitamin supplement through 1979.

Although a spoonful of caviar supplies the adult daily requirement of vitamin B-12, it is also high in cholesterol and salt.

Although some argue that developing a disease from B12 deficiency by following a sensible diet is extremely rare — less than one chance in a million, there are cases to suggest that vegetarians and vegans who are not taking vitamin B < sub > 12 </ sub > supplements or food fortified with B < sub > 12 </ sub >, do not consume sufficient servings of B < sub > 12 </ sub > and have abnormally low blood concentrations of vitamin B < sub > 12 </ sub >.

It is rich in essential nutrients including vitamin C. Although it is believed to have been cultivated for several thousand years, its history as a domesticated plant is not clear before Greek and Roman times, when it was a well-established garden vegetable.

Although it is not enzymatically active, it is structurally related to several serine proteases of the coagulation cascade: factors VII, IX, X and protein C. The carboxyglutamate residues ( which require vitamin K ) bind protein Z to phospholipid surfaces.

Although often considered a classic finding in multiple sclerosis, it can be caused by a number of conditions, including transverse myelitis, Behçet's disease, trauma, radiation myelopathy, vitamin B12 deficiency ( subacute combined degeneration ), and compression of the spinal cord in the neck from any cause such as cervical spondylosis, disc herniation, tumor, and Arnold-Chiari malformation.

Although these fruits are reputed to contain high amounts of ascorbic acid ( vitamin C ), 445 mg / 100g, the specific contents are disputed, and the overall antioxidant strength of amla may derive instead from its high density of ellagitannins such as emblicanin A ( 37 %), emblicanin B ( 33 %), punigluconin ( 12 %) and pedunculagin ( 14 %).

Although he is perfectly willing to cooperate with Scotland Yard, Holmes has nothing but contempt for the intelligence and mentality of the police.

Although we continue to pay our conversational devotions to `` free private enterprise '', `` individual initiative '', `` the democratic way '', `` government of the people '', `` competition of the marketplace '', etc., we live rather comfortably in a society in which economic competition is diminishing in large areas, bureaucracy is corroding representative government, technology is weakening the citizen's confidence in his own power to make decisions, and the threat of war is driving him economically and physically into the ground ''.

Although it is constantly made to look foolish ( too simple to come in out of the rain, people say, who have found in the innocent an impediment ), it does not mind looking foolish because it is not concerned with how it looks.

Although open to the general public it is not overcrowded ; ;

Although we have no measures of its strength or intensity, the heritage of the doctrine of inalienable rights is retained.

Although because of the important achievements of nineteenth century scholars in the field of textual criticism the advance is not so striking as it was in the case of archaeology and place-names, the editorial principles laid down by Stevenson in his great edition of Asser and in his Crawford Charters were a distinct improvement upon those of his predecessors and remain unimproved upon today.

Although Patchen has given previous evidence of an interest in jazz, the musical group that he works with, the Chamber Jazz Sextet, is often ignored by jazz critics.

Although the false glamour surrounding bourbon or other whisky commercials is possibly no more fatuous than the pseudo-sophistication with which TV soft-drinks are downed or toothpaste applied, there is a sad difference between enticing a viewer into sipping Oopsie-Cola and gulling him into downing bourbon.

Although the United States and the U.S.S.R. have been arguing whether there shall be four, five or six top assistants, the most important element in the situation is not the number of deputies but the manner in which these deputies are to do their work.

`` Although it is not the best of which he is capable '', said Shelley as he closed the book, `` it is still poetry of a high order ''.

Although Sam Rayburn affects a gruff exterior in many instances, nevertheless he is fundamentally a man of warm heart and gentle disposition.

Although a similar situs for tangible property is mentioned in the statute, this is cancelled out by the provision that definite kinds of property `` and all other tangible property '' situated or being in any town is taxable where the property is situated.

Although much of the Industrial Division's promotional effort is devoted to securing new locations and expansions by major industries, small business is also afforded considerable attention.

Although Mr. Brown was not himself its inventor ( it was a French idea ), it is typical that his intuition first conceived the importance of mass producing this basic tool for general use.

Although lacking absolute verisimilitude, they supply the ear and the imagination with all necessary materials for re-creation of the original.

Although the elections were for local officials, it was not necessary to conduct the elections so as to prevent parties from publicly identifying their candidates.

Although they are often considered to be weeds in gardens, this viewpoint is not always necessary, as most of them die when the soil temperature warms up again in early to late spring when other plants are still dormant and have not yet leafed out.

Although Chamberlain survived this, the reputation of his administration was so badly damaged that it was clear that a coalition government was necessary.

Although some authorities see the Torah as commanding Jews to believe in God, Jews see belief in God as a necessary, but not sufficient, condition for a Jewish life.

Trailing zeros after the decimal point are not necessary, although in science, engineering and statistics they can be retained to indicate a required precision or to show a level of confidence in the accuracy of the number: Although 0. 080 and 0. 08 are numerically equal, in engineering 0. 080 suggests a measurement with an error of up to one part in two thousand (± 0. 0005 ), while 0. 08 suggests a measurement with an error of up to one in two hundred ( see significant figures ).

Although the characters ' voices are recorded in a studio, ADR is necessary whenever members of the cast cannot all be present at once.

Although Diophantus made important advances in symbolism, he still lacked the necessary notation to express more general methods.

Although some form of reaction may take place, it is not necessary ; the method may work by attractive charges, for example, if the target particles are positively charged, use a negatively charged substrate.

Although the wine gallon had been used for centuries for import duty purposes there was no legal standard of it in the Exchequer and a smaller gallon was actually in use, so this statute became necessary.

Although the 1984 – 1985 squad was made up of a healthy mix of emerging players and mature stars, at the beginning of the season no one would have regarded the team as having the necessary ingredients to make it to the end.

Although older than both Boulton and Darwin, by 1758 Whitehurst was writing to Boulton telling excitedly of a pyrometer he had built, and looking forward to visiting Birmingham " to spend one day with you in trying all necessary experiments ".

Although longbows were much faster and more accurate than the black powder weapons which replaced them, longbowmen always took a long time to train because of the years of practice necessary before a war longbow could be used effectively ( examples of longbows from the Mary Rose typically had draws greater than ).

Although the Basic Law states that the Macau SAR government may " when necessary " ask the central government to allow the garrison to assist in maintaining public order or disaster relief, Chief Executive Ho has said that, in keeping with the Basic Law the garrison will play no role in internal security.

Although managing the parliament was among the necessary skills of holding high office, they did not depend on a parliamentary majority for their power.

Although the Sovereign was not stripped of the ancient prerogative powers and legally remained the head of government, politically it gradually became necessary for him or her to govern through a Prime Minister who could command a majority in Parliament.

Although input / output devices continued to be mapped into memory addresses, some additional programming was necessary to set up the added bus interfaces.

Although these polymers have other properties of of contemporary protein as well, identity with the latter is not a necessary inference ". Some theories of abiogenesis propose that proteinoids were a precursor to the first living cells.

Although the above equations are the most used form in literature, some comments about the notation are necessary.

Although this sometimes resulted in inefficient command according to some American historians, the Party leadership considered political control over the military absolutely necessary, as the Army relied more and more on officers from the pre-revolutionary Imperial period and understandably feared a military coup.

Although some concerned Mohawk citizens have contested the racially-exclusive membership policy, the Canadian Human Rights Tribunal has ruled that the Mohawk government may adopt policies it deems necessary to ensure the survival of its people.

Although an SSTO rocket might theoretically be built, margins would be likely to be very thin: even comparatively minor problems could mean that the craft may fail to achieve the necessary mass-fraction to reach orbit with useful payload.

Although the proof is necessary to produce a theorem, it is not usually considered part of the theorem.

Although Kambei had judged that seven samurai would be necessary, time is running short.

Although government is formed in the lower house, the House of Representatives, the support of the Senate is necessary in order to govern.