In order to keep the cytotoxic cells from killing cells just for presenting self-proteins, self-reactive T cells are deleted from the repertoire as a result of tolerance ( also known as negative selection ).

As the loads are usually fixed, an acceptable design will result from combination of a material selection procedure and geometry modifications, if possible.

Critics of the SAP argue in favor of a weak anthropic principle ( WAP ) similar to the one defined by Brandon Carter, which states that the universe's ostensible fine tuning is the result of selection bias: i. e., only in a universe capable of eventually supporting life will there be living beings capable of observing any such fine tuning, while a universe less compatible with life will go unbeheld.

Mutations and natural selection result in a species acquiring new traits and eventually evolving into one or more new species.

Cooking technique, known as culinary art, generally requires the selection, measurement, and combining of ingredients in an ordered procedure in an effort to achieve the desired result.

Because early humans that were quick to fear dangerous situations were more likely to survive and reproduce, preparedness is theorized to be a genetic effect that is the result of natural selection.

Both height and skull size increases probably result from a combination of phenotypic plasticity and genetic selection over this period .< ref >

It may require the selection, measurement and combining of ingredients in an ordered procedure in an effort to achieve the desired result.

These inherited traits are usually the result of a combination of natural crosses and artificial selection methods aimed at producing horses for specific tasks.

However, under Abdullah II Al-Sabah, Kuwait pursued a general pro-Ottoman foreign policy, formally taking the title of Ottoman provincial governor, however this relationship with the Ottoman Empire did result in Ottoman interference with Kuwaiti laws or selection or rulers.

As a result, the selection of one or both secondaries should be changed so that the TD lines of the new combination are closer to right angles.

Market forces that result in a biased presentation include the ownership of the news source, concentration of media ownership, the selection of staff, the preferences of an intended audience, and pressure from advertisers.

The abundance of some genetic changes within the gene pool can be reduced by natural selection, while other " more favorable " mutations may accumulate and result in adaptive changes.

However, natural selection is " blind " in the sense that changes in phenotype ( physical and behavioral characteristics ) can give a reproductive advantage regardless of whether or not the trait is heritable ( non heritable traits can be the result of environmental factors or the life experience of the organism ).

Selection for a trait may also result in the selection of other correlated traits that do not themselves directly influence reproductive advantage.

The viability of produced gametes can differ, while intragenomic conflicts such as meiotic drive between the haploid gametes can result in gametic or " genic selection ".

Ecological selection covers any mechanism of selection as a result of the environment ( including relatives, e. g. kin selection, competition, and infanticide ), while " sexual selection " refers specifically to competition for mates.

The end result of natural selection is two populations that are both optimally adapted to their specific environment, while both perform substandard in the other environment.

A prerequisite for natural selection to result in adaptive evolution, novel traits and speciation, is the presence of heritable genetic variation that results in fitness differences.

The exuberant tail of the peacock is thought to be the result of sexual selection by females.

When such mutations result in a higher fitness, natural selection will favor these phenotypes and the novel trait will spread in the population.

As a result of the relatively simple and easy-to-understand circumstances of the adaptation, the peppered moth has become a common example used in explaining or demonstrating natural selection to laypeople and classroom students.

Similarly, the language spread to numerous other parts of the world as a result of British trade and colonization elsewhere and the spread of the former British Empire, which, by 1921, held sway over a population of 470 – 570 million people, approximately a quarter of the world's population at that time.

The 8051 microcontroller has two, a primary accumulator and a secondary accumulator, where the second is used by instructions only when multiplying ( MUL AB ) or dividing ( DIV AB ); the former splits the 16-bit result between the two 8-bit accumulators, whereas the latter stores the quotient on the primary accumulator A and the remainder in the secondary accumulator B.

Failure to abide by the former may result in a foul or wallet slap.

As a result, Switzer resigned as head coach in January 1998 and former Steelers offensive coordinator Chan Gailey was hired to take his place.

As a result, former mayor Phil Yerington publicly expressed the view that if they " let Mother Nature take her course, we'll all be better off ".

As a result, former party chairpersons Fritz Kuhn and Claudia Roth ( who had been elected to parliament that year ) were no longer able to continue in their executive function and were replaced by former party secretary general Reinhard Bütikofer and former Bundestag member Angelika Beer.

Australia's ties with the UK dwindled rapidly as Britain closed foreign bases, disengaged from its former territories East of Suez and began courting the EEC, as a result of which American investment in Australia increased dramatically and Australia's onetime enemy Japan replaced the UK as Australia's major trading partner.

As a result, much territories of former Vijaynagar Empire were captured by Deccan Sultanates and the remaining got divided into many states ruled by Hindu rulers.

The former result opened the door for " working mathematicians " to assume the axiom of choice in their proofs.

Kutia was also part of a common Eastern Orthodox tradition in the Russian Empire, which had waned in popularity as a result of the official atheism of the former Soviet Union, but has had a subsequent resurgence in Ukraine, Belarus and other former Soviet Republics.

However, in the following years, slums called musseques-which had existed for decades-began to grow out of proportion and stretched for miles beyond Luanda's former city limits, as a result of the decades-long civil war, and because of the rise of deep social inequalities due to large-scale migration of civil war refugees from other Angolan regions.

This is the result of the unification of the opposition: Vice-President Doy Laurel was elected as the president of the Nacionalista Party, with former Labor Secretary and Assemblyman Blas Ople emerged as the Executive Vice-President and former Defense Minister Juan Ponce Enrile as the Secretary-General

Although the Republican Party and Democratic Party chapters in Puerto Rico have selected voting delegates to the national nominating conventions since the early 1900s, public interest in these processes heightened as a result of the efforts of a group of Democratic statehooders led by Franklin Delano López in 1976 to elect delegates supporting former Georgia Gov.

Subsequently both the statehood faction and the commonwealth shared control on a 50-50 basis from 1984 to 1988 and lost control that year as a result of their defeat in an internal primary that year between PDP forces led by then Senate president Miguel Hernández Agosto and NPP forces led by former Gov.

Columbushaus was the result of a plan by the French retail company Les Galeries Lafayette, whose flagship store was the legendary Galeries Lafayette in Paris, to open a counterpart in Berlin, on the Grand Hotel Belle Vue's former site, but financial worries made them pull out.

The migration of many former slaves and their descendants to major urban centers like Memphis and north to New York City, Detroit, Chicago, Cleveland and Buffalo ( See: Second Great Migration ( African American )) meant that black and white residents were living in close proximity in larger numbers than ever before, and as a result heard each other's music and even began to emulate each other's fashions.

The latter was a result of the Pythagorean theorem and the former the assumption that a + b ≤ c. The contradiction means that it is impossible for both to be true and it is known that the Pythagorean theorem holds.

The Pontifical Commission Ecclesia Dei is a commission of the Roman Catholic Church established by Pope John Paul II's motu proprio Ecclesia Dei of 2 July 1988 for the care of those former followers of Archbishop Marcel Lefebvre who broke with him as a result of his consecration of four priests of his Society of St. Pius X as bishops on 30 June 1988, an act the Holy See deemed illicit and schismatic.

In May 1987, Senegal extradited Captain Moulaye Asham Ould Ashen, a former black member of the Haidalla government accused of corruption, but only after veiled threats from Nouakchott that failure to do so would result in Mauritania's allowing Senegalese dissidents a platform from which to speak out against the government of President Abdou Diouf.

The former ten-year moratorium on the construction of new nuclear power plants was the result of a citizens ' initiative voted on in 1990 which had passed with 54. 5 % Yes vs. 45. 5 % No votes ( see Nuclear power in Switzerland for details ).

As a result, Johnson eventually left the team after their XXVIII win and was replaced by former University of Oklahoma head coach Barry Switzer, who had one of the highest winning percentages of any college football coach in history with a mark of. 837.