Before the actual process of cell death is precipitated by enzymes, apoptotic signals must cause regulatory proteins to initiate the apoptosis pathway.

Before the development of silicon power rectifier diodes, cuprous oxide and later selenium was used ; its low efficiency gave it a much higher forward voltage drop ( typically 1. 4 to 1. 7 V per " cell ", with multiple cells stacked to increase the peak inverse voltage rating in high voltage rectifiers ), and required a large heat sink ( often an extension of the diode ’ s metal substrate ), much larger than a silicon diode of the same current ratings would require.

Before a cell divides, the DNA is copied, so that each of the resulting two cells will inherit the DNA sequence.

Before leaving, Dillinger ran the wooden pistol along the bars of the cell in which the people were held and cracked that he had broken their escape proof jail with nothing but a wooden gun.

Before the trial concluded, Meinhof was found hanged in her cell in 1976.

Before the 1980s, it was often speculated that cannabinoids produced their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors.

Before he can escape in this manner, Dworkin Barimen, the keeper of the Pattern, appears out of nowhere, having seemingly walked through the dungeon wall from a neighboring cell.

Brain manages to snatch the keys away from Dr. Claw and open the cell where Gadget has been interrogating " the fake Santa " using lines of The Night Before Christmas for reference.

Before the local protein synthesis hypothesis gained significant support, there was general agreement that the protein synthesis underlying L-LTP occurred in the cell body.

Before leaving the cell, she murders the interrogator who was torturing her for info.

Before his seminal research all cultured cell lines were immortal and aneuploid.

Before cell division begins, the interphase MTOC replicates to form two distinct MTOCs ( now typically referred to as centrosomes ).

Before they reach her, however, Mona breaks out of her cell and manages to escape the station.

Before differential centrifugation can be carried out to separate different portions of a cell from one another, the tissue sample must first be homogenised.

Before its identification, its function has been hypothesized for as much as 30 years as being linked to the cell surface receptor c-Mpl, and in older publications thrombopoietin is described as c-Mpl ligand ( the agent that binds to the c-Mpl molecule ).

Before the introduction of number portability, 314 was used for all cell phones originating in the 636 area code.

Before I knew it, I was in the middle of my cell floor on my knees.

Before the documentary aired, he gave Madonna a cell phone number ; he claimed that at any point during the airing Madonna could call Leach and argue any point.

Before Ethan can do anything, Ryan uses his cell phone's memory to contact Ethan and makes a deal directly over the phone: the videotape in exchange for the Martin family.

Before the game, an arsonist named Unger ( Charles Tyner ), schemes to kill Crewe by setting off an incendiary device in his cell.

Before his sentence could be carried out, he hanged himself in his cell.

Before it begins to develop, the morphological characteristics of a MSC are: a small cell body with a few cell processes that are long and thin ; a large, round nucleus with a prominent nucleolus that is surrounded by finely dispersed chromatin particles, giving the nucleus a clear appearance ; a small amount of Golgi apparatus, rough endoplasmic reticulum, mitochondria, and polyribosomes ; and the cells are widely dispersed within an extracellular matrix that is devoid of every type of collagen except for a few reticular fibrils.

Before merging them into a common profile it is well to remember that their separate careers were extraordinary.

His first book, Before The Brave ( 1936 ), is a collection of poems that are almost all Communistic, but after publication of this book he rejected Communism, and advocated a pacifistic anarchy, though retaining his revolutionary idiom.

Before deciding where it is going, however, a college or university must know where it is.

Before it cycles on again, humidity can build up and make you uncomfortable even though the temperature is still low.

Before adjournment Monday afternoon, the Senate is expected to approve a study of the number of legislators allotted to rural and urban areas to determine what adjustments should be made.

Before dropping the anchor, the fishing process is reversed, and the anchor is dropped from the end of the cathead.

Before the mention of Alemanni in the time of Caracalla, you would search in vain for Alemanni in the moderately detailed geography of southern Germany in Claudius Ptolemy, written in Greek in the mid-2nd century ; it is likely that at that time, the people who later used that name were known by other designations.

Before the 16th century, harvest was the term usually used to refer to the season, as it is common in other West Germanic languages to this day ( cf.

Before the end of this World Cup Glenn McGrath stated that Lara is the greatest batsman that he has ever bowled to.

Before the formation of Malaysian Federation, the Philippines claimed that the Malaysian state of Sabah in north Borneo is within their territorial rights based on historical facts of the Sultanate of Sulu's leasing agreement with the North Borneo Company, is presently an unresolved claim against Malaysia.

Before this discovery, it is widely believed that bricks appeared about 3000 years ago in the Western Zhou dynasty since the earliest bricks were found in Western Zhou ruins.

In Earnest J. Gaines ' novel, " A Lesson Before Dying " Bayonne, Louisiana is the name of a Cajun town central to the book.

Before the renovations the entire building was all male, but now every house is co-ed.

Before 1873, England had two parallel court systems: courts of " law " that could only award money damages and recognized only the legal owner of property, and courts of " equity " ( courts of chancery ) that could issue injunctive relief ( that is, a court order to a party to do something, give something to someone, or stop doing something ) and recognized trusts of property.

Before the Norman conquest in 1066, justice was administered primarily by what is today known as the county courts ( the modern " counties " were referred to as " Shires " in pre-Norman times ), presided by the diocesan bishop and the sheriff, exercising both ecclesiastical and civil jurisdiction.

Before 1938, the federal courts, like almost all other common law courts, decided the law on any issue where the relevant legislature ( either the U. S. Congress or state legislature, depending on the issue ), had not acted, by looking to courts in the same system, that is, other federal courts, even on issues of state law, and even where there was no express grant of authority from Congress or the Constitution.

Before the 1970s, community colleges in the United States were more commonly referred to as junior colleges, and that term is still used at some institutions.

This act is commonly criticized by modern cartoonists including Watterson and Pearls Before Swines Stephan Pastis.

Before there was an official standard for C, many users and implementors relied on an informal specification contained in a book by Ritchie and Brian Kernighan ; that version is generally referred to as " K & R " C. In 1989 the American National Standards Institute published a standard for C ( generally called " ANSI C " or " C89 ").

BCE is the abbreviation for Before the Common / Current / Christian Era ( an alternative to Before Christ, abbreviated BC ).