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Benzodiazepines share a similar chemical structure, and their effects in humans are mainly produced by the allosteric modification of a specific kind of neurotransmitter receptor, the GABA < sub > A </ sub > receptor, which increases the conductance of this inhibitory channel ; this results in the various therapeutic effects as well as adverse effects of benzodiazepines.
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Benzodiazepines and similar
** Benzodiazepines, particularly alprazolam, flunitrazepam, triazolam, temazepam, and nimetazepam Z-drugs like Zimovane have a similar effect in the body to Benzodiazepines.
Benzodiazepines and their
Benzodiazepines exert their anxiolytic properties at moderate dosage.
* Benzodiazepines are well known for their strong muscle-relaxing properties and can be useful in the treatment of muscle spasms, although tolerance often develops to their muscle relaxant effects.
Benzodiazepines are the most well-known and most frequently-prescribed hypnotic medications, although their use in recent years is being increasingly replaced by newer nonbenzodiazepine hypnotic drugs and the hormone melatonin.
Benzodiazepines are effective in the short term but tolerance to their hypnotic effects develops after 1 or 2 weeks, thus making them ineffective for long-term use.
Benzodiazepines tend to exert their hypnotic effects at high dosage compared to the more moderate dosage needed for anxiolytic effects to be felt.
Benzodiazepines may be useful in acute treatment of severe symptoms but the risk benefit ratio is against their long-term use in phobic disorders.
Benzodiazepines gained widespread use in the 1970s for anxiety and depression, until dependency problems curtailed their popularity.
Benzodiazepines may influence neurosteroid metabolism by virtue of their actions on translocator protein ( TSPO ; " peripheral benzodiazepine receptor ").
Benzodiazepines and effects
Prescription hypnotics ( Benzodiazepines and Nonbenzodiazepines included ) should therefore be taken for the shortest duration of time with the least frequency possible, so as to avoid tolerance, drug dependence, and the adverse effects of long term use.
Benzodiazepines, such as lorazepam, enhance the effects of GABA at the GABA < sub > A </ sub > receptor via increasing the frequency of opening of the chloride ion channel on the GABA < sub > A </ sub > receptors ; which results in the therapeutic actions of benzodiazepines.
Benzodiazepines, a class of psychoactive drugs called the " minor " tranquilizers, have varying hypnotic, sedative, anxiolytic, anticonvulsant, and muscle relaxing properties, but they may create the exact opposite effects.
Benzodiazepines are prescribed for generalized anxiety disorder and show beneficial effects in the short term.
Benzodiazepines including nitrazepam may inhibit the glucuronidation of morphine leading to increased levels of and prolongation of the effects of morphine in rat experiments.
Benzodiazepines and are
Benzodiazepines are prescribed for short-term relief of severe and disabling anxiety.
Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid ( GABA-A ), resulting in sedative, hypnotic ( sleep-inducing ), anxiolytic ( anti-anxiety ), anticonvulsant, and muscle relaxant properties ; also seen in the applied pharmacology of high doses of many shorter-acting benzodiazepines are amnesic-dissociative actions.
Benzodiazepines are categorized as either short -, intermediate-or long-acting.
Benzodiazepines are commonly misused and taken in combination with other drugs of abuse.
Benzodiazepines possess sedative, hypnotic, anxiolytic, anticonvulsant, muscle relaxant, and amnesic actions, which are useful in a variety of indications such as alcohol dependence, seizures, anxiety, panic, agitation and insomnia.
Benzodiazepines are usually administered orally ; however, very occasionally lorazepam or diazepam may be given intravenously for the treatment of panic attacks.
Benzodiazepines are the preferred choice in the management of alcohol withdrawal syndrome, in particular, for the prevention and treatment of the dangerous complication of seizures and in subduing severe delirium.
Benzodiazepines are sometimes used in the treatment of acute anxiety, as they bring about rapid and marked or moderate relief of symptoms in most individuals ; however, they are not recommended beyond 2 – 4 weeks of use due to risks of tolerance and dependence and a lack of long-term effectiveness.
Benzodiazepines are often prescribed for a wide range of conditions:
* Benzodiazepines are effective as medication given a couple of hours before surgery to relieve anxiety.
* Benzodiazepines are also used to treat the acute panic caused by hallucinogen intoxication.
Benzodiazepines are also used to calm the acutely agitated individual and can, if required, be given via an intramuscular injection.
* Benzodiazepines are sometimes used for obsessive compulsive disorder, although they are generally believed to be ineffective for this indication ; effectiveness was, however, found in one small study.
Benzodiazepines are sometimes prescribed to treat behavioral symptoms of dementia.
Benzodiazepines are the first line of treatment, and high doses are often required.
Benzodiazepines, such as lorazepam, are the drugs of choice to control agitation and seizures ( when present ).
Benzodiazepines are often used to reduce anxiety symptoms, muscle tension, seizure disorders, insomnia, symptoms of alcohol withdrawal, and panic attack symptoms.
Benzodiazepines are still among the most widely prescribed sedative-hypnotics in the United States today.
Benzodiazepines and by
Benzodiazepines were implicated in 39 % of suicides by drug poisoning in Sweden, with nitrazepam and flunitrazepam accounting for 90 % of benzodiazepine implicated suicides, in the elderly over a period of 2 decades.
Benzodiazepines such as midazolam are more commonly used due largely to a lack of a marketing effort by the pharmaceutical companies.
Benzodiazepines are not known to reduce dissociative symptoms ; however, they do target the often comorbid anxiety and stress experienced by those with DPD and, thus, lead to global improvement.
Benzodiazepines and receptor
Benzodiazepines all bind unselectively to the GABA < sub > A </ sub > receptor.
Benzodiazepines and GABA
Benzodiazepines are given to control seizures ; as they also modulate GABA receptors they may potentially increase the effect of pyridoxine.
Benzodiazepines ( Valium ) bind to the α and δ subunits of GABA receptors in order to improve GABAergic signaling.
Benzodiazepines are given to control seizures ; as they also modulate GABA receptors they may potentially increase the effect of pyridoxine.
Benzodiazepines and which
# Benzodiazepines, such as diazepam, which often in addition to symptom relief assist in staying asleep and reducing awakenings from the movements
Benzodiazepines and ;
Benzodiazepines have a reputation with patients and doctors for causing a severe and traumatic withdrawal ; however, this is in large part due to the withdrawal process's being poorly managed.
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