By 2008, sales in the US reached $ 14. 6 billion, the biggest selling drugs in the US by therapeutic class.

By the end of his sole rule ( AD 14 ), Augustus had expanded the empire to the line of the Danube river, which was to remain its central / eastern European border for its entire history ( except for the occupation of Dacia 105-275 ).

By 14 he had already written a short adventure novel called The Black Diamonds which was lost for years until published in 2002.

By the end of the season, the rookie quarterback had rewritten the record book in Charlotte and many more in the NFL ( including most passing yards by a rookie with 4, 051, previously held by Peyton Manning with 3, 739 ; and most rushing touchdowns by a QB with 14 ).

By 1 July 1933 there were 1, 463 working camps with 250, 000 junior enrollees ( 18 – 25 years of age ), 28, 000 veterans, 14, 000 American Indians, and 25, 000 Locally Enrolled ( or Experienced ) Men ( LEM ).

By 1534 the Spanish crown had determined to split the region in two parallel lines, forming the governorship of " Nueva Castilla " ( from the 1 ° to the 14 ° latitude, close to Pisco ), and that of " Nueva Toledo " ( from the 14 ° to the 25 ° latitude, in Taltal, Chile ), assigning the first to Francisco Pizarro and the second to Diego de Almagro.

By 1990, floorball was recognized in 7 countries, and by the time of the first European Floorball Championships in 1994, that number had risen to 14.

By comparison, recent figures ( as of 14 November 2008 ) estimate Zimbabwe's annual inflation rate at 89. 7 sextillion ( 10 < sup > 21 </ sup >) percent., which corresponds to a monthly rate of 5473 %, and a doubling time of about five days.

By forging Mathieu as an absolute rationalist, analyzing every situation, and functioning entirely on reason, he removed any strands of authentic content from his character and as a result, Mathieu could " recognize no allegiance except to self " ( Sartre 1942: 13 ), though he realized that without " responsibility for my own existence, it would seem utterly absurd to go on existing " ( Sartre 1942: 14 ).

By 1952 a multiracial pattern of quotas allowed for 14 European, 1 Arab, and 6 Asian elected members, together with an additional 6 African and 1 Arab member chosen by the governor.

By the time Lewis and Clark arrived at the mouth of the Columbia, at least 14 maritime fur traders had already visited the river's mouth and estuary.

By the end of the Renaissance the number of courses had grown to ten, and during the Baroque era the number continued to grow until it reached 14 ( and occasionally as many as 19 ).

By 1949 Schaeffer's compositional work was known publicly as musique concrète ( Palombini 1993, 14 ).

By September, Porsche owned a 35. 14 % plurality stake in Volkswagen AG, effectively giving it control over the company.

By one single battle, the Battle of Agnadello on 14 May 1509, the dominion of Venice in Italy was practically lost.

By 1907, over 14, 000 clerks were providing service over of railroad.

By halftime, New England owned a surprising 14 – 3 lead.

Total dead 2, 050, 89-Other estimates of German casualties are as follows: By UK War Office in 1922: Killed 1, 808, 545 exclusive of 14, 000 African conscript deaths during the war By US War Dept in 1924: 1, 773, 700 killed and died.

* By this year, the Portuguese colony of Brazil has between 400 mills producing 57, 000 tons of sugar a year and 230 mills producing 14, 000 tons ( estimates vary ) The wealth the Portuguese acquire from selling sugar in Europe prompts the English and French to follow suit in this century.

By the end of September, 14 women including Bridget Bishop and 5 men had been hanged.

* April 14 – By the Treaty of Krakow, Poland and Hungary recognize the independence of Moldavia.

By the 12th century Italian flutes came in a variety of sizes, and fragments of 12th-century Norman bone whistles have been found in Ireland, and an intact 14 cm Tusculum clay whistle from the 14th century in Scotland.

By 14: 30, General Steinmetz, the commander of the First Army, unilaterally launched his VIII Corps across the Mance Ravine in which the Prussian infantry were soon pinned down by murderous rifle and mitrailleuse fire from the French positions.

By late January, the plague is in full retreat, and the townspeople begin to celebrate the imminent opening of the town gates.

By the 1st century BC, Aediles were elected in July, and took office on the first day in January.

By January 1, 1995, the order of battle of the Belarusian army had changed.

Morton wrote the column until 1975 ; it was revived in January 1996 and continues today, written by William Hartston, though the name " By the Way " has been dropped in favour of simply " Beachcomber ".

By January 2000, the remaining stock was valued in the millions.

By the end of January 1918, the Investigatory Commission of Petrograd Soviet ( probably same as of Revtribunal ) petitioned Sovnarkom to delineate the role of detection and judicial-investigatory organs.

By January 1972, Berg introduced through his letters that he was God's prophet for this time, further establishing his spiritual authority within the group.

By January 1934, the second year of the CCC program, 300, 000 men were enrolled.

By contrast, in January 2001, just three dot-coms bought advertising spots during Super Bowl XXXV.

" By 7 January, that storyline had generated the most complaints in show history: the BBC received about 8, 500 complaints, and media regulator Ofcom received 374.

By the first days of January, Emperor Menelik, accompanied by his Queen Taytu Betul, had led large forces into Tigray, and besieged the Italians for 15 days ( 6 – 21 January 1896 ), trying in vain to storm the fort on several occasions, until the Italians surrendered with permission from the Italian Headquarters.

By January 1937 he was at Alcubierre above sea level, in the depth of winter.

By the end of January 1959 the new army had reached a strength of around 2, 000 officers and soldiers.

By mid-December to early January, the majority are usually found between Monterey and San Diego, often visible from shore.

By late December to early January, eastern grays begin to arrive in the calving lagoons of Baja.

By January 1943, Himmler reported that 629, 000 ethnic Germans had been resettled ; however, most resettled Germans did not live in the envisioned small farms, but in temporary camps or quarters in towns.

By 25 January, Operation North Wind had officially ended.

By late 1824, Monroe approved Calhoun's plans and in a special message to the Senate on January 27, 1825, requested the creation of the Arkansas Territory and Indian Territory.

By January 1944, Germany had diplomatic relations with only a handful of countries: Argentina, Ireland, Vichy France, the Salo Republic in Italy, Occupied Denmark, Sweden, Finland, Slovakia, Hungary, Romania, Croatia, Bulgaria, Switzerland, the Holy See, Spain, Portugal, Turkey, Thailand, Japan, and the Japanese puppet states of Manchukuo and the Wang Jingwei regime in China.

By January 1645 the Parliamentary forces in Coventry had strengthened their hold on the castle and attempts by Royalist forces to dislodge them from Warwickshire failed.

By January 1970, Zambia had acquired majority holding in the Zambian operations of the two major foreign mining interests, the Anglo American Corporation and the Rhodesia Selection Trust ( RST ); the two became the Nchanga Consolidated Copper Mines ( NCCM ) and Roan Consolidated Mines ( RCM ), respectively.

By 1923, the fate of the area had still not been decided, prompting Lithuanian forces to invade in January 1923 and seize the port.

By the time of the January 1983 Winter NAMM Show, Smith was able to demonstrate a MIDI connection between his Prophet 600 analog synthesizer and a Roland JP-6.

By January 1983, Men at Work had the top album and single in both the US and the UK-a feat never achieved previously by an Australian act.