* 1642 – Cosimo III de ' Medici, Grand Duke of Tuscany ( d. 1723 )

Thus while among his own colleagues he seemed merely a hypocritical and arrogant priest, in his relations with his brother humanists, such as Cosimo de ' Medici, he appeared as the student of classical antiquities and especially of Greek theological authors ".

* 1574 – Cosimo I de ' Medici, Grand Duke of Tuscany ( b. 1519 )

In 1716 Cosimo III de ' Medici, Grand Duke of Tuscany issued an edict legislating that the three villages of the Lega del Chianti as well as the village of Greve and a 2 mile ( 3 km ) hillside north of Greve near Spedaluzza as the only officially recognized producers of Chianti.

The original zone dictated by the edict of Cosimo III de ' Medici would eventually be considered the heart of the Chianti Classico region.

In 1716 Cosimo III de ' Medici, Grand Duke of Tuscany issued an edict legislating that the three villages of the Lega del Chianti ( Castellina in Chianti, Gaiole in Chianti, and Radda in Chianti ) as well as the village of Greve and a 2-mile ( 3-km ) stretch of hillside north of Greve near Spedaluzzo as the only officially recognized producers of Chianti.

They had two children: Cosimo III, Tuscany's longest reigning monarch, and Francesco Maria de ' Medici, a prince of the Church.

* 1469 – Piero di Cosimo de ' Medici of Florence ( b. 1416 )

The Medici reigned Grand Dukes of Tuscany starting with Cosimo I de ' Medici in 1569, until the death of Gian Gastone de ' Medici in 1737.

Cosimo de ' Medici was the first Medici family member to essentially control the city from behind the scenes.

During Sforza's reign, Florence was under the command of Cosimo de ' Medici and the two rulers became close friends.

In 1605, Galileo had been employed as a mathematics tutor for Cosimo de ' Medici.

Galileo initially called his discovery the Cosmica Sidera (" Cosimo's stars "), in honour of Cosimo II de ' Medici ( 1590 – 1621 ).

Cosmipharus ( after Cosimo de ' Medici ) and IV.

* 1519 – Cosimo I de ' Medici, Grand Duke of Tuscany ( d. 1574 )

After the death of Cosimo II de ' Medici in 1621, he returned to Nancy where he lived for the rest of his life, visiting Paris and the Netherlands later in the decade.

Maybe also that this hilltop dwelling, commissioned by Giovanni de ' Medici, Cosimo il Vecchio's second son, with its view over the city, is the very first example of a Renaissance villa: that is to say it follows the Albertian criteria for rendering a country dwelling a " villa suburbana ".

Lorenzo's grandfather, Cosimo de ' Medici, was the first member of the Medici family to combine running the Medici bank with leading the Republic.

* 1590 – Cosimo II de ' Medici, Grand Duke of Tuscany ( d. 1621 )

It was commissioned by Duke Ranuccio I for the visit of Cosimo I de ' Medici.

Pope Innocent VII ( probably1339 – 6 November 1406 ), born Cosimo de ' Migliorati, was briefly Pope at Rome between 1404 and 1406 during the period of the Western Schism ( 1378 – 1417 ) while there was a rival Pope, Antipope Benedict XIII, at Avignon.

****** son Cosimo I de ' Medici, Grand Duke of Tuscany married Eleanor of Toledo

* 1389 – Cosimo de ' Medici, Italian ruler ( d. 1464 )

Galileo asked whether he should name the moons the " Cosmian Stars ," after Cosimo alone, or the " Medician Stars ," which would honor all four brothers in the Medici clan.

At Cosimo's suggestion, Galileo changed the name to Medicea Sidera (" the Medician stars "), honouring all four Medici brothers ( Cosimo, Francesco, Carlo, and Lorenzo ).

He was also named Console of the prestigious Accademia delle Arti del Disegno of Florence, founded by the Duke Cosimo I, at 13 January 1563, under the influence of Vasari.

As a 12-year old boy, he became a pupil of Cosimo Rosselli, and a fellow-pupil with Fra Bartolomeo with whom he formed such an intimate brotherly rapport that in 1494 the two started their own studio in Florence.

* September 27 – Cosimo de ' Medici, ruler of Florence ( d. 1464 )

* December 2 – Piero di Cosimo de ' Medici, ruler of Florence ( b. 1416 )

** Cosimo de ' Medici, ruler of Florence ( d. 1464 )

The political alliance between Francesco Sforza and the Florence of Cosimo de ' Medici bore architectural fruit, as Milanese building came under the influence of Brunelleschian models of Renaissance architecture.

In the Renaissance the philosopher Marsilio Ficino set up an Academy under the patronage of Cosimo de Medici in Florence, mirroring that of Plato.

* August 26 – A conspiracy against Piero di Cosimo de ' Medici, led by Luca Pitti and Borso d ' Este, is discovered and put down in Florence.

* August 1 – Cosimo de ' Medici, ruler of Florence ( b. 1389 )

** Piero di Cosimo de ' Medici, ruler of Florence ( d. 1469 )

* September – Cosimo de ' Medici, later the de facto ruler of Florence and patron of Marsilio Ficino, is exiled by the Albizzi / Strozzi faction.

* September – Cosimo de ' Medici returns to Florence one year, to the day, following his exile by the Alberti and Strozzi faction.

The House of Medici or Famiglia de ' Medici ( ; ) was a political dynasty, banking family and later royal house that first began to gather prominence under Cosimo de ' Medici in the Republic of Florence during the late 14th century.

Cosimo, Piero, and Lorenzo, three successive generations of the Medici, ruled over Florence through the greater part of the 15th century, without altogether abolishing representative government, yet while clearly dominating it.

This exile lasted only until 1512, however, and the " senior " branch of the family — those descended from Cosimo the Elder — were able to rule on and off until the assassination of Alessandro de ' Medici, first Duke of Florence, in 1537.

The Castration of Uranus ( mythology ) | Uranus: fresco by Vasari & Cristofano Gherardi ( c. 1560, Sala di Cosimo I, Palazzo Vecchio, Florence ).

When Cosimo was exiled from Florence, Donatello went to Rome, remaining until 1433.

Donatello died in Florence in 1466 and was buried in the Basilica of San Lorenzo, next to Cosimo de ' Medici the Elder.

Carnesecchi was in Venice when the news reached him, and betook himself to Florence, where, thinking himself safe, he was betrayed by Duke Cosimo I de ' Medici, who wished to curry favour with the pope.

Many of his pictures still exist, the most important being the wall and ceiling paintings in the great Sala di Cosimo I of the Palazzo Vecchio in Florence, where he and his assistants were at work from 1555, and the frescoes he started inside the vast cupola of the Duomo, completed by Federico Zuccari and with the help of Giovanni Balducci.

The Castration of Uranus: fresco by Vasari & Cristofano Gherardi ( c. 1560, Sala di Cosimo I, Palazzo Vecchio, Florence ).

* Eleanor of Toledo ( 1522 – 1562 ), Duchess of Florence, wife of Cosimo I