Despite his inelegant appearance — many in the audience thought him awkward and even ugly — Lincoln demonstrated an intellectual leadership that brought him into the front ranks of the party and into contention for the Republican presidential nomination.

Despite their structural simplicity and possession of properties comparable with RNA, the chemically plausible generation of " simpler " nucleic acids under prebiotic conditions has yet to be demonstrated.

Despite a demonstrated appearance of blunted affect, recent findings indicate that many individuals diagnosed with schizophrenia are emotionally responsive, particularly to stressful or negative stimuli, and that such sensitivity may cause vulnerability to symptoms or to the disorder.

Despite the difference in styles, Taft had demonstrated for the most part that the substance of his policies echoed those of Roosevelt.

Despite the team's losing record, the Warriors demonstrated that they could be a tough opponent with a healthy lineup and a strong bench.

Despite these claims, no pheromonal substance has ever been demonstrated to directly influence human behavior in a peer reviewed study.

Despite the village's location in the northern state of Wisconsin, studies demonstrated that it was feasible for new buildings to achieve a majority of their heat from solar energy.

Despite Hirt's statement years later " I'm not a jazz trumpeter and never was a jazz trumpeter ", he made a few recordings where he demonstrated ability to play in that style during the 1950s, with bandleader Monk Hazel and a few other recordings on the local Southland Records label.

Despite these demonstrated abilities, wild Rock Doves are sedentary and rarely leave their local areas.

Despite mild paraparesis, they were able to stand, walk, perform demanding motor test and demonstrated no signs of incontinence.

Despite his youth, he had demonstrated his strength in several general elections when he had been able to get as many as twenty MPs elected to seats he controlled through his family's wealth and political patronage.

Despite the generosity that King Jun had demonstrated, Wiman revolted and destroyed Gojoseon.

Despite these claims, the assignment of the work to Diego Hurtado de Mendoza was generally accepted, until Alfred Paul Victor Morel-Fatio, in 1888, demonstrated the untenability of that candidate.

Despite its illegality due to the Anti-Socialist Laws of 1878, the Social Democratic Party of Germany's use of the limited universal male suffrage were " potent " new methods of struggle which demonstrated their growing strength and forced the dropping of the Anti-Socialist legislation in 1890, Engels argued.

Despite the demonstrated loyalty, IV Scythica was not involved in actual fighting because it was not considered a high quality legion.

Despite their previous band's status as gothic rock icons, Love and Rockets moved towards a slightly brighter and more pop-influenced sound, as demonstrated by their first minor hit being a cover of the Motown classic " Ball of Confusion ".

Despite her own success she supported other performers during the Music Hall War of 1907, when performers demonstrated outside theatres for better pay and conditions.

Despite the success demonstrated by the exercise, it would be the last time that the division mounted something similar the national service scheme was modified to limit the size of each yearly intake of trainees and the size of the CMF was reduced by over 30, 000 men in an effort to free up Regular personnel to raise the 1st Brigade.

Despite this, however, Ramakrishna demonstrated that Bhakti could be practiced as an inner retreat to experience solace in the face of Western-style discipline and often discrimination in the workplace.

Despite possible risks of assassination, Bülow persuaded Wilhelm to make a visit to Tangier in 1905, where he made a speech supporting Morocco's independence, but his presence there simultaneously demonstrated Germany's determination to maintain its own influence.

Despite many plausible sources of involuntary celibacy, none have been clearly demonstrated.

Despite his political affiliation, Astor quickly demonstrated his independence by his support for the so-called " People's Budget " and the National Insurance Act of 1911.

Despite her short career in parliament, she demonstrated that women could successfully seek election, and it was not long before a second woman ( Catherine Stewart in 1938, elected for Wellington West ) entered parliament.

Despite anecdotal reports of improvement, no large, controlled trials have demonstrated significant, persistent improvement, and GH is not a common or standard treatment for either condition.

Despite the efficacy of epilepsy surgery, some patients decide not to undergo surgery owing to fear or the uncertainty of having a brain operation.

" And in a June 2009 article published in the Journal of ECT, Iranian researchers observe that, " Despite the wide consensus over the safety and efficacy of electroconvulsive therapy ( ECT ), it still faces negative publicity and unfavorable attitudes of patients and families.

Despite their well-established efficacy, indications for monoamine oxidase inhibitors are currently very limited, due to their significant potential for adverse effects, many interactions, and the availability of newer and safer ( although not necessarily more efficacious ) antidepressants.

Despite some evidence showing that all the major therapeutic orientations are about of equal effectiveness, there remains much debate about the efficacy of various forms treatment in use in clinical psychology.

Despite its relative technical simplicity, the injection ( grafting ) technique for breast augmentation is accompanied by post-procedure complications — fat necrosis, calcification, and sclerotic nodules — which directly influence the technical efficacy of the procedure, and of achieving a successful outcome.

Despite literature on Dance Therapy dating back to the 1940s, there remains no scientific evidence what so ever for the therapeutic efficacy of DMT.

Despite its excellence in vitro efficacy, the frequently reported inability of penicillin to eradicate GABHS from patients with acute and relapsing tonsillitis is a cause for concern.

Despite an extensive amount of research in the USSR, ( by 1984, more than 1, 500 pharmacological and clinical published studies ), the concept is not generally recognized in Western countries as it seemed to be in contrast to some of the key concepts of modern pharmacology: potency, selectivity and with efficacy balanced by an accepted level of toxicity.

Despite a number of studies funded by the Cuban government, which produces and markets the drug, One independent clinical trial has found no evidence of the efficacy of policosanol.

Despite the loss, Cleveland players took home a number of awards.

Despite the drop on popularity of the romantic dramas, some of them have enjoyed big box office and critical success, as the controversial, groundbreaking Brokeback Mountain ( 2005 ) for example, that won several awards and Slumdog Millionaire ( 2008 ), a critically acclaimed romantic-drama that has been nominated for ten Academy Awards, and went on to win eight of them, including Best Picture.

Despite ZZ Top's popularity and success in the 1970s, it wasn't until the 1980s that they started winning major awards and honors.

Despite some controversy, the movie received critical acclaim and the award at the movie festival in Sochi, a Special Jury Award and the FIPRESCI Award at an international festival in Turin, the awards in Cottbus, and the Grand Prix in Trieste.

Despite retiring, Moore couldn't escape the limelight, and received numerous awards and dedications.

Despite mixed critical reaction to the film, O ' Toole's performance was universally praised and garnered numerous prestigious awards and prizes, including an Academy Award nomination for Best Actor.

Despite its limited run, it is regarded as one of the most groundbreaking and influential commercials of the 2000s, and received more awards from the television and advertising industries than any commercial in history.

Despite the company's small size, FTL products were consistently number-one sellers and received the highest critical acclaim and industry awards.

Despite its mixed critical and poor commercial response, Fire Walk with Me gained attention at awards time.

Despite its numerous awards for performance excellence, PAFB was closed on September 29, 1995 in a round of national base closures in the early 1990s as the Air Force began to pare down its post-Cold War missions.

Despite performing poorly at the box office, the film was nominated for several awards, including Golden Globes for Best Director and Best Picture ( Drama ) and Oscars for best Best Art Direction ( Richard Sylbert, George Gaines ) and Film Editing.

Despite Birmingham's mediocre 2004 – 05 season, Heskey was named as the club's Player's Player of the Season, Fan's Player of the Season, finished as top goalscorer with 11 goals and won most Man of the match awards.

Despite the criticism, Bloom won two awards for his performance.

Despite its poor commercial performance, Videodrome won a number of awards upon its release.

Despite only receiving modest ratings and never winning major television awards, The Wire has been described by many critics as the greatest television series ever made and one of the most accomplished works of fiction of the 2000s.

Despite its censorship, " Hurricane " was praised by critics and was nominated for several awards, including the MTV Video Music Award for Best Direction.

Despite the difficulties in keeping the four mellophoniums ( which formed their own separate section ) in tune, this particular Kenton orchestra had its exciting moments ; the albums " Adventures in Jazz " and " West Side Story " ( arrangements by Johnny Richards ) each won Grammy awards in 1962 and 1963.

Despite this, Owen was the most popular member of the group, on account of his boyish good looks and sweet demeanour, regularly earning awards such as Smash Hit's " Most Fanciable Male in the World " and " Best Haircut ".

Despite critical acclaim and a number of awards, initially no renewal was made after the second season ( 2003 ).

Despite his numerous career-related awards, Hanna was most proud of this Distinguished Eagle Scout Award.

Despite receiving awards when built, the Tricorn Centre was voted the third ugliest building in Britain and was demolished in 2004 to mixed reactions and protests from an unrepentant Luder.

Despite multiple awards, appeals from multiple U. S. Senators, and despite having maintained his integrity by not backing down, Secretary Rusk removed Otepka from his position and ultimately fired him.

Despite multiple awards, appeals from multiple U. S. Senators, and not backing down, Secretary Rusk removed Otepka from his position and ultimately unceremoniously fired him.

Despite only receiving modest ratings and never winning major television awards, The Wire has been described by many critics as the greatest TV drama of all time.