During the Han dynasty, Zhang Zhongjing, who was mayor of Changsha near the end of the 2nd century AD, wrote a Treatise on Cold Damage, which contains the earliest known reference to the Neijing Suwen.

The earliest original writings in Coptic language were the letters by St. Anthony of Egypt, first of the “ Desert Fathers .” During the 3rd and 4th centuries many ecclesiastics and monks wrote in Coptic, among them, St. Pachomius, whose monastic rule ( the first cenobitic rule, for solitary monks gathered in communities ) survives only in Coptic.

During 1893 the juvenile quality of his earliest work falls away, and by 1894 his career as a painter can be said to have begun.

The earliest spring-driven timepiece with a second hand which marked seconds is an unsigned clock depicting Orpheus in the Fremersdorf collection, dated between 1560 and During the 3rd quarter of the 16th century, Taqi al-Din built a clock with marks every 1 / 5 minute.

During the 1230s, a city wall was built, enclosing 38 hectares, when the earliest stone houses on the Rennweg were built as well.

During the Archaic ( please see Archaic Greece ) and early Classical periods ( about the 6th and early 5th centuries BCE ), the architectural forms of the earliest temples had solidified and the Doric ( see Classical order ) emerged as the predominant element.

During the island's earliest history it became the domain of Jean Lafitte, the famed pirate and American hero of the War of 1812.

During the Register's earliest years in the late 1960s and early 1970s, organization was lax and SHPOs were small, understaffed, and underfunded.

" During shooting, Bogart was already suffering from the earliest symptoms of the throat cancer that would eventually kill him.

During the earliest years of the reign of Menes, according to Manetho, the seat of power was further to the south, at Thinis.

During its earliest years, the station was affiliated with NBC, ABC, DuMont, and the CMQ Television Network.

During its earliest years, the location was usually spelled as " Cranberry ".

During the British colonial period, the earliest settlers of European descent arrived in this portion of the colony of New Jersey.

During this time, seeds began to be offered for sale in Europe, the earliest known dating from 1813, with John Fraser offering four species in London, followed by Flanagan & Nutting offering nine species in their 1835 catalog.

During the earliest Chinese dynasties, the area in what is now Jiangsu was far removed from the center of Chinese civilization, which was in the northwest Henan ; it was home of the Huai Yi ( 淮夷 ), an ancient ethnic group.

During this time, Bradfield had tried writing lyrics, but this later changed and Wire wrote all their earliest lyrics, leaving Bradfield, alongside the classically-trained Sean Moore when he joined, to write the music.

During this era the earliest global-scale continent-continent collisional belts developed.

During the earliest Paleozoic Era, the continent that would later become North America straddled the equator.

During a visit to Sicily in 1816, Meyerbeer noted down a number of folksongs, and these in fact constitute the earliest collection of folk music of the region.

During this time, papers on the Apollo program missions and some of the earliest reports on AIDS were published.

During the earliest era of air combat in World War I, a small number of frontline German fighter pilots serving with what would become known as the Luftstreitkräfte wore hard bridge pince-nez frames for their corrective lenses, including the very first pilot to defeat an opposing aircraft ( on July 1, 1915 ) using a synchronized machine-gun armed aircraft, Leutnant Kurt Wintgens.

During this time, St. Paul's College and St. Joseph's College competed in the earliest inter-school football matches ever played in the colony.

During its earliest stages, it is sometimes known as Bowen's disease.

During this time, and in spite of the attacks, the city of Vigo developed its earliest commerce, and was given several privileges by the kings of Spain.

During the first half of October the Blue Ridge and other parts of the Appalachians provide a spectacle stretching from Maryland and West Virginia to Georgia.

During the Vietnam War, between 1962 and 1971, the United States military sprayed nearly of material containing chemical herbicides and defoliants mixed with jet fuel in Vietnam, eastern Laos and parts of Cambodia, as part of Operation Ranch Hand.

During the Vietnam War, between 1962 and 1971, the United States military sprayed nearly of chemical herbicides and defoliants in Vietnam, eastern Laos and parts of Cambodia, as part of the aerial defoliation program known as Operation Ranch Hand.

During World War II, large parts of Berlin were destroyed in the 1943 – 45 air raids and during the Battle of Berlin.

During the Civil war, soldiers from different parts of the United States played baseball together, leading to a more unified national version of the sport.

During the Middle Ages, most of the remainder of Europe was Christianized, with Christians also being a sometimes large religious minority in the Middle East, North Africa, Ethiopia and parts of India.

During Lent, capybara meat is especially popular in parts of South America, especially in Venezuela, as the Catholic Church, in a special dispensation, is claimed to have allowed eating capybara meat when meat consumption was otherwise not allowed.

During the late Middle Ages, Flanders ' trading towns ( notably Ghent, Bruges and Ypres ) made it one of the richest and most urbanized parts of Europe, weaving the wool of neighbouring lands into cloth for both domestic use and export.

During the Cold War, the northern parts of Asia were communist controlled with the Soviet Union and People's Republic of China, while western allies formed pacts such as CENTO and SEATO.

During its lifetime, information may pass through many different information processing systems and through many different parts of information processing systems.

During printing, water adhered to the gum arabic surfaces and avoided the oily parts, while the oily ink used for printing did the opposite.

During the three years a number of battles took place in different parts of Afghanistan.

During this transition period, which gradually eased the performance of more demanding " natural " brass writing, many composers ( notably Wagner and Berlioz ) still notated brass parts for the older " natural " instruments.

During the " pan and scan " process, an editor selects the parts of the original filmed composition that seem to be the focus of the shot and makes sure that these are copied ( i. e. " scanned ").

During his pontificate vigorous measures were taken against the heresies which had broken out in Germany, England, and other parts of Europe ; a sincere effort was also made to cause a reformation in the various monastic orders.

During the years 550 to 330 BC, coinciding with the sovereignty of the first Persian Empire over the Middle East area, especially the whole part of the Persian Gulf and some parts of the Arabian Peninsula, the name of " Pars Sea " is widely found in the compiled written texts.

During this time, substantial glaciers advanced and retreated over much of North America and Europe, parts of South America and Asia, and all of Antarctica.

During his long reign, Ivan the Terrible nearly doubled the already large Russian territory by annexing the three Tatar khanates ( parts of disintegrated Golden Horde ): Kazan and Astrakhan along the Volga River, and Sibirean Khanate in South Western Siberia.

During partial eclipses most sunlight is blocked by the Moon passing in front of the Sun, but the uncovered parts of the photosphere have the same surface brightness as during a normal day.

During the same period, the UN International Monitoring Group ( IMG ) published a report claiming that the Somali government's security forces were ineffective and corrupt, and that up to half of the food aid that was destined for the conflict-stricken parts of the country was being misdirected.

During this season, periodic squalls occur and sometimes tropical cyclones bring overcast skies and rains to the southwest, northeast, and eastern parts of the island.

During this time, German cultural and ethnic influence increased as a result of immigration from German-speaking parts of the Holy Roman Empire.

During his brief stay in Nagoya Castle in what is today Saga prefecture, on Kyūshū, Hideyoshi memorized the shite ( lead roles ) parts of ten Noh plays, which he then performed, forcing various daimyō to accompany him onstage as the waki ( secondary, accompanying role ).

During the Livonian War in the 16th century, southern parts of the Livonian Confederation and Tartu fell under rule of the Grand Duchy of Lithuania,