Hereditary inclusion body myopathies comprise both autosomal recessive and autosomal dominant muscle disorders that have a variable expression ( phenotype ) in individual patients, but all share similar structural features in the muscles.

Hereditary inclusion body myopathy ( IBM ) constitutes a unique group of neuromuscular disorders characterized by adult-onset slowly progressive distal and proximal weakness, and a typical muscle pathology including rimmed vacuoles and filamentous inclusions.

# REDIRECT Hereditary inclusion body myopathy

* Hereditary diseases that cause damage to the liver include hemochromatosis, involving accumulation of iron in the body, and Wilson's disease, which causes the body to retain copper.

Gitxsan Nation is one of Canada's First Nations and is a name used when referring to the Office of the Hereditary Chiefs of the Gitxsan, which is the formal governing body of the Gitxsan people.

* Mindjedef-" King ’ s son of his body ", " Hereditary prince ", " Treasurer of the King of Lower Egypt ", etc.

The Office of the Hereditary Chiefs is the main political body of the Wet ' suwet ' en and is involved in the negotiating process for an eventual treaty with the British Columbia government.

:* The Hereditary spherocytosis ( HS ) syndromes are a group of inherited disorders characterized by the presence of spherical-shaped erythrocytes on the peripheral blood smear.

The male-line descendants of Grand Duchess Charlotte who are the children of a reigning Grand Duke or The Hereditary Grand Duke hold the titles Prince ( ss ) of Luxembourg and Prince ( ss ) of Nassau with the style of His / Her Royal Highness.

Male line descendants of Grand Duchess Charlotte who are not the children of a Grand Duke or Hereditary Grand Duke are Prince ( ss ) of Nassau with the style of His / Her Royal Highness ( coming from their status as male-line descendants of Duke Robert of Parma ).

Of these 92, 1 is the Earl Marshal, a hereditary office always held by the Duke of Norfolk, 1 is the Lord Great Chamberlain, a hereditary office held in gross, currently by the Marquess of Cholmondeley, and the other 90 are elected by other Hereditary Peers.

Hereditary spastic paraplegias are classified based on the symptoms ; on their mode of inheritance ; on the patient ’ s age at onset ; and, ultimately, on the gene associated with the condition.

Hereditary abnormalities of fibrinogen ( the gene is carried on chromosome 4 ) are of both quantitative and qualitative in nature and include afibrinogenaemia, hypofibrinogenaemia, dysfibrinogenaemia, and hypodysfibrinogenaemia.

* Hereditary spastic paraplegia-a group of inherited disorders that are characterized by progressive weakness and stiffness of the legs

Staffordshire Bull Terriers are known to suffer from Hereditary Cataracts ( HC ) and L-2-hydroxyglutaric aciduria ( L2HGA )— a metabolic disorder resulting in behavioural changes and dementia-like symptoms — both of which are detectable via DNA tests.

The various individuals who hold fractions of the Lord Great Chamberlainship are technically each Joint Hereditary Lord Great Chamberlain, and the right to exercise the office for a given reign rotates proportionately to the fraction of the office held.

Horemheb's specific titles are outlined from his Saqqara tomb which was built while he was still only an official: " Hereditary Prince, Fan-bearer on the Right Side of the King, and Chief Commander of the Army "; the " attendant of the King in his footsteps in the foreign countries of the south and the north "; the " King's Messenger in front of his army to the foreign countries to the south and the north "; and the " Sole Companion, he who is by the feet of his lord on the battlefield on that day of killing Asiatics.

When Tutankhamun died while still a teenager, Horemheb had already been officially designated as the rpat or iry-pat ( basically the " Hereditary or Crown Prince ") and idnw (" Deputy of the King " in the entire land ) by the child pharaoh ; these titles are found inscribed in Horemheb's then private Memphite tomb at Saqqara which dates to the reign of Tutankhamun since the child king's ...

The children are, respectively, second, fourth and third in the line of succession to the Monegasque throne, after their mother, HRH the Princess of Hanover, Hereditary Princess of Monaco.

Included are traditional stories about creation and other phenomena told by Aboriginal people such as Mi ' kmaq Hereditary Chief Stephen Augustine who recounts the beginning of the world in the Creation Stories Theatre film.

The Marquesses are also Hereditary Constables of Hillsborough Fort.

Hereditary spherocytosis is a genetically-transmitted ( autosomal dominant ) form of spherocytosis, an auto-hemolytic anemia characterized by the production of red blood cells that are sphere-shaped rather than bi-concave disk shaped ( Donut-Shaped ), and therefore more prone to hemolysis.

Hereditary spherocytosis is an autosomal dominant or recessive trait, most commonly ( though not exclusively ) found in Northern European and Japanese families, although an estimated 25 % of cases are due to spontaneous mutations.

Hereditary supporters are normally limited to hereditary peers, certain members of the Royal Family, chiefs of Scottish Clans, Scottish feudal barons whose baronies predate 1587.

Hereditary genetic disorders such as neurofibromatoses ( type 1 and type 2 ) and tuberous sclerosis complex are known to predispose to their development.

Among his 29 titles are: Master of the Royal Household of Scotland and Hereditary Keeper of the Great Seal of Scotland ( ranking 25th in the Scottish Order of Precedence ), Admiral of the Western Coasts and Isles, and the Chief of Clan Campbell.

The Hereditary Chiefs who are leading Tla-o-qui-aht through this process are:

There is currently a standing agreement that decisions regarding resource use are done through consensus of the six Hereditary Chiefs.

Currently, regionally focused appointments are made by the Hereditary Chiefs.

Charcot-Marie-Tooth disease ( CMT ), also known as Hereditary Motor and Sensory Neuropathy ( HMSN ), Hereditary Sensorimotor Neuropathy ( HMSN ), or Peroneal Muscular Atrophy, is a heterogeneous inherited disorder of nerves ( neuropathy ) that is characterized by loss of muscle tissue and touch sensation, predominantly in the feet and legs but also in the hands and arms in the advanced stages of disease.

Also known as Hereditary Motor and Sensory Neuropathy ( HMSN ), it is genetically heterogeneous and usually presents in the first decade of life with delayed motor milestones, distal muscle weakness, clumsiness and frequent falls.

Hereditary Spastic Paraplegia ( HSP ), also called Familial Spastic Paraplegias or Strumpell-Lorrain disease, is a group of inherited diseases whose main feature is progressive stiffness and contraction ( spasticity ) in the lower limbs, as a result of damage to dysfunction of the nerves.

* Hereditary Spastic Paraplegia-a group of clinically and genetically diverse disorders that share a primary feature, which is the causation of progressive and generally severe lower extremity weakness and spasticity.

On 24 June 1928, a group of 12 Russian Hereditary Commanders met in Paris to re-establish the activities of the Russian Grand Priory.

Reasoning that eminence is caused by genetic traits, he did a study of their heritability, publishing it in 1869 as Hereditary Genius.

The genetic basis of HD was discovered in 1993 by an international collaborative effort spearheaded by the Hereditary Disease Foundation.

Samoyeds can be affected by a genetic disease known as " Samoyed Hereditary Glomerulopathy ", a renal disease.

As yet there is no genetic screening test available for Samoyed Hereditary Glomerulopathy.

* Hereditary spherocytosis, a genetic disorder marked by hemolytic anemia

Due to the heavy influx of American Quarter Horse breeding, some Paints may also carry genetic disorders such as Hyperkalemic Periodic Paralysis ( HYPP ), Hereditary Equine Regional Dermal Asthenia ( HERDA ), Equine polysaccharide storage myopathy ( called PSSM-polysaccharide storage myopathy-in Paints, Quarter Horses and Appaloosas ), Malignant hyperthermia ( MH ) and Glycogen Branching Enzyme Deficiency ( GBED ).

Examples of genetic tendencies include Protein C deficiency, Protein S deficiency, the Factor V Leiden mutation, Hereditary anti-thrombin deficiency and Prothrombin Mutation G20210A.

Hereditary hemorrhagic telangiectasia ( HHT ), also known as Osler-Weber-Rendu disease and Osler-Weber-Rendu syndrome, is a genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver and brain.

Hereditary angioedema ( HAE ) exists in three forms, all of which are caused by a genetic mutation that is inherited in an autosomal dominant form.

Lynch syndrome ( HNPCC or Hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin.

* inherited or genetic diseases ( Familial Dysautonomia, Hereditary Sensory Autonomic Neuropathy )

** Sub-specialties: Hereditary and genetic eye diseases