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If a receptor tyrosine kinase ( RTK ) is involved in activating the pathway, the isozyme PLC-γ has tyrosine residues that can become phosphorylated upon activation of an RTK, and this will activate PLC-γ and allow it to cleave PIP < sub > 2 </ sub > into DAG and IP < sub > 3 </ sub >.
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If and receptor
If the change in electrical potential is large enough, it evokes an action potential, which is transmitted along the axon of the receptor cell, into the spinal cord.
If the receptor for growth hormone is itself affected, the condition may prove harder to treat.
If D1 receptors were a critical component of the mechanism of AAP blocking just the D1 receptor would improve the psychiatric symptoms that are exhibited.
If D1 receptor binding was a critical component of the action of antipsychotics they would need to be present in maintenance dosages.
If the compression forces were closer to the fovea the resulting compression would cause a greater amount of macropsia at lower field angles with little effect at higher field angles where the receptor distribution is not as compressed.
If a neurotransmitter binds to a receptor with a reversal potential that is higher than the threshold potential for the postsynaptic neuron, the postsynaptic cell will be more likely to generate an action potential and an excitatory postsynaptic potential will occur ( EPSP ).
If receptor activation takes place in a lipid raft, the signalling complex is protected from non-raft enzymes such as membrane phosphatases.
If the target cell has a known specific pinocytotic receptor, drugs can be attached and will be internalized.
If a ligand for an orphan receptor is later discovered, the receptor is referred to as an " adopted orphan ".
If an endogenous ligand is found, the orphan receptor is " adopted ".
If the protein is a receptor, ligand binding may result in agonism or antagonism.
If we were only to look at the eye-optic channel at the instant that light hit the receptor surface, we would know nothing of depth of field, focus, or perspective.
If and tyrosine
If tyrosine and a system generating hydrogen peroxide are added to a cell-free homogenate of the thyroid, large quantities of free mono-iodotyrosine can be formed ( Alexander, 1959 ).
If this reaction does not take place, phenylalanine accumulates and tyrosine is deficient.
If the homodimer fails to form, efficient tyrosine phosphorylation of DAB1 in vitro fails.
If an investigation involves a protein that requires tyrosine phosphorylation, the kinase must be supplied in the form of a tyrosine kinase gene.
If and kinase
If not, it is an inactive kinase.
If rhabdomyolysis is suspected, serum myoglobin, creatine kinase, lactate dehydrogenase, electrolytes and renal function will be checked.
If and is
If the circumstances are faced frankly it is not reasonable to expect this to be true.
If his dancers are sometimes made to look as if they might be creatures from Mars, this is consistent with his intention of placing them in the orbit of another world, a world in which they are freed of their pedestrian identities.
If a work is divided into several large segments, a last-minute drawing of random numbers may determine the order of the segments for any particular performance.
If they avoid the use of the pungent, outlawed four-letter word it is because it is taboo ; ;
If Wilhelm Reich is the Moses who has led them out of the Egypt of sexual slavery, Dylan Thomas is the poet who offers them the Dionysian dialectic of justification for their indulgence in liquor, marijuana, sex, and jazz.
If he is the child of nothingness, if he is the predestined victim of an age of atomic wars, then he will consult only his own organic needs and go beyond good and evil.
If it is an honest feeling, then why should she not yield to it??
If he thus achieves a lyrical, dreamlike, drugged intensity, he pays the price for his indulgence by producing work -- Allen Ginsberg's `` Howl '' is a striking example of this tendency -- that is disoriented, Dionysian but without depth and without Apollonian control.
If love reflects the nature of man, as Ortega Y Gasset believes, if the person in love betrays decisively what he is by his behavior in love, then the writers of the beat generation are creating a new literary genre.
If he is good, he may not be legal ; ;
If the man on the sidewalk is surprised at this question, it has served as an exclamation.
If the existent form is to be retained new factors that reinforce it must be introduced into the situation.
If we remove ourselves for a moment from our time and our infatuation with mental disease, isn't there something absurd about a hero in a novel who is defeated by his infantile neurosis??
If many of the characters in contemporary novels appear to be the bloodless relations of characters in a case history it is because the novelist is often forgetful today that those things that we call character manifest themselves in surface behavior, that the ego is still the executive agency of personality, and that all we know of personality must be discerned through the ego.
If he is a traditionalist, he is an eclectic traditionalist.
If our sincerity is granted, and it is granted, the discrepancy can only be explained by the fact that we have come to believe hearsay and legend about ourselves in preference to an understanding gained by earnest self-examination.
If to be innocent is to be helpless, then I had been -- as are we all -- helpless at the start.
If and involved
If Arthur Williams was involved in the fraud or the murder, then he too had another identity.
If possible, he should make an appointment in order that all persons involved may be present.
If, after that, they breach the order, proceedings can be started and in theory the person involved can be sent to prison.
If instrumentation is involved, the researcher is expected to calibrate his / her instrument by applying it to known standard objects and documenting the results before applying it to unknown objects.
If very small amounts of solution are involved, most of the solution may be soaked up by the filter medium.
If sexual passion is also involved, this condition is called paraphilia.
# If A is a disjoint union of countably many disjoint Lebesgue measurable sets, then A is itself Lebesgue measurable and λ ( A ) is equal to the sum ( or infinite series ) of the measures of the involved measurable sets.
If there is a side pot, players involved in the side pot should show their hands before anyone who is all-in for only the main pot.
If all functions involved in the expression are pure functions, then the expression is referentially transparent.
If Gold Silver Copper Standard is involved, expect gold to be even more powerful, while silver still has its own powers.
" If the claimant is involved in wrongdoing at the time the alleged negligence occurred, this may extinguish or reduce the defendant's liability.
* If the upper cervical cord is involved, all four limbs may be involved and there is risk of respiratory paralysis ( segments C3, 4, 5 to diaphragm ).
If a purchaser of car insurance policy is involved in an accident wherein the liability for the accident is undisputedly of their insured driver, then the insurance carrier has the duty to indemnify their insured driver in very specific ways to make them " whole " again.
If the check in operation succeeds, then the version numbers of all files involved automatically increment, and the CVS-server writes a user-supplied description line, the date and the author's name to its log files.
* If all clubs involved have played each other twice:
* If two legged games between all clubs involved have not been played, or the tie is not broken by the rules above, it is broken using:
If a state can preserve the fiction that migrations are the result of innumerable " personal " decisions, then the state may be able to justify its stand that it has not been culpably involved.
If or when it is involved, it is an initiating mechanism.
" If similar trade goods were involved in the Manhattan arrangement ", Burrows and Wallace surmise, " then the Dutch were engaged in high-end technology transfer, handing over equipment of enormous usefulness in tasks ranging from clearing land to drilling wampum.
If there exists no route back to the source address, the packet is assumed to be malformed or involved in a network attack, and is dropped.
If the person requested to testify ( deponent ) is a party to the lawsuit or someone who works for an involved party, notice of time and place of the examination before trial can be given to the other side's attorney, but if the witness is an independent third party, a subpoena must be served on him / her if he / she is recalcitrant.
If the indirect work of employees involved in producing chemicals and machinery are taken into account, the ratio of labor to output is higher.
As an example of the federal bureaucracy involved, Georgia Rep. Jack Kingston said, " If you move a polling place from the Baptist church to the Methodist church, you've got to go through the Justice Department.
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