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1519 and Charles
In 1519, already reigning as Carlos I in Spain, Charles took up the imperial title as Karl V. The balance ( and imbalance ) between these separate inheritances would be defining elements of his reign, and would ensure that personal union between the Spanish and German crowns would be short-lived.
Charles V was the last to be a crowned Emperor ( elected 1519, crowned 1530 ); his successors were all Emperors by election (; ) only.
On the approach of the imperial election of 1519, Joachim's vote was eagerly solicited by the partisans of King Francis I of France, and Charles of Burgundy.
Cabot returned to Spain in 1530 and informed Emperor Charles V ( 1519 – 56 ) about his discoveries.
In 1507 he was appointed tutor to Emperor Maximilian I's ( 1493 – 1519 ) seven year old grandson, Charles, who was later to become Emperor Charles V ( 1519 – 56 ).
He continued to serve in that role throughout the remainder of Paul III's papacy after which he was replaced to placate the Holy Roman Emperor Charles V ( 1519 – 56 ).
He finally accepted Charles V of Spain as inevitable, and the election of Charles ( 28 June 1519 ) revealed Leo's desertion of his French alliance.
Having outlived his father Philip, Charles succeeded Maximilian as Holy Roman Emperor in 1519, and thus ruled both the Holy Roman Empire and the Spanish Empire simultaneously.
At first, this policy seemed successful, and Maximilian managed to secure the votes from Mainz, Cologne, Brandenburg and Bohemia for his grandson Charles V. The death of Maximilian in 1519 seemed to put the succession at risk, but in a few months the election of Charles V was secured.
On taking over the kingdom in 1519, Emperor Charles V granted the lordship of Les Valls, as it was then known, to Germaine of Foix ’ s line in perpetuity.
Mary and Maximilian ’ s grandson Charles became king of Spain as Charles I in 1516 and Holy Roman emperor as Charles V in 1519.
Charles, now backed by France, fought Maximilian's grandson Charles of Habsburg ( who became Holy Roman Emperor, as Charles V, in 1519 ) in the Guelderian Wars and expanded his realm further north, to incorporate what is now the Province of Overijssel.
Charles V (; ; ; ; 24 February 1500 – 21 September 1558 ) was ruler of the Holy Roman Empire from 1519 and, as Charles I, of the Spanish Empire from 1516 until his voluntary retirement and abdication in favor of his younger brother Ferdinand I and his son Philip II in 1556.
In 1519, Charles became Holy Roman Emperor and Archduke of Austria.
The unanimous decision of the electors gave Charles the crown on 28 June 1519.

1519 and married
* Maximilian ( 1459 – 1519 ), Holy Roman Emperor, married
In 1487 he married his elder son Franceschetto Cybo ( d. 1519 ) to Maddalena de ' Medici ( 1473 – 1528 ), the natural daughter of Lorenzo de ' Medici, who in return obtained the cardinal's hat for his thirteen-year-old son Giovanni, later Pope Leo X.
* Dorothea of Brandenburg ( c. 1446 – March, 1519 ), married Duke John V of Saxe-Lauenburg on 12 February 1464.
He married Blanche of Montferrat ( Bianca di Montferrato ) ( 1472 – 1519 ) who after Charles's death was the regent of the Duchy of Savoy from 1490 to 1496.
* Lady Eleanor Brandon ( 1519 – 27 September 1547 ), who married Henry Clifford, 2nd Earl of Cumberland.
Henry married Catherine de ' Medici ( 13 April 1519 – 5 January 1589 ) on 28 October 1533, when they were both fourteen years old.
In 1519 he married Girolama Francesca di Braghetis, also of Correggio, who died in 1529.
# Lady Eleanor Brandon ( 1519 – 27 September 1547 ); she married Henry Clifford, 2nd Earl of Cumberland
On 1 September 1519 he married Kunigunde Creutzer ( 1502-1560 ), who died in 1560.
In order to acquire a safe passage for him and his armies to cross the Yusufzai territory and invade the capital of the Afghan Lodi Empire in Delhi, India, Babur married Mubarika Yusufzai, the daughter of the Yusufzai chief Shah Mansur Yusufzai, on January 20, 1519.
It was about 1535 – 1545, probably at Boulogne that he married the daughter of Christopher Ashton, ( b 1493 ) who was born about 1519 and who bore him a son, Roger Dudley.
He married thirdly, Lady Mary Stafford, daughter of Edward Stafford, 3rd Duke of Buckingham and Lady Eleanor Percy around June 1519 and had issue.
In St. Gall, he was appointed city physician and on August 18, 1519, he married Martha Grebel, the sister of Conrad Grebel who would later become a leading figure of the Anabaptist movement.
On 16 February 1519, Henry married Ursula Pole, the daughter of Margaret Pole, 8th Countess of Salisbury and Sir Richard Pole.

1519 and young
Holbein also painted the occasional portrait in Basel, among them the double portrait of Jakob and Dorothea Meyer, and, in 1519, that of the young academic Boniface Amerbach.
George's earliest biographer suggests that George may have spent time in France as a child when his father was on embassy from January 1519, and suggests this as a reason how George could speak such perfect French from a young age and as an explanation as to how Anne and George remained so close during their formative years.
After the Medici pope Leo X's brief attempt to establish a young Medici as duke, thwarted by the early death of Lorenzo II de ' Medici in 1519, Urbino was ruled by the dynasty of Della Rovere dukes ( see also War of Urbino ).
In 1519, the young King Charles I granted the Germanies ( literally " brotherhoods ") permission to arm themselves to fight off the Muslim raiders.

1519 and b
* 1574 – Cosimo I de ' Medici, Grand Duke of Tuscany ( b. 1519 )
* 1591 – Pope Innocent IX ( b. 1519 )
* 1560 – Imagawa Yoshimoto, Japanese daimyo ( b. 1519 )
* April 21 – Cosimo I de ' Medici, Grand Duke of Tuscany ( b. 1519 )
* September 17 – Pedro Menéndez de Avilés, first Spanish Governor of Florida ( b. 1519 )
* February 23 – Andrea Cesalpino, Italian philosopher, physician, and botanist ( b. 1519 )
* July – Girolamo Mei, Italian historian and humanist ( b. 1519 )
* October 13 – Theodore Beza, French theologian ( b. 1519 )
** Edwin Sandys, English prelate ( b. 1519 )
* June 18 – Henry Fitzroy, 1st Duke of Richmond and Somerset, illegitimate son of Henry VIII of England ( b. 1519 )
* December 30 – Pope Innocent IX ( b. 1519 )
* January 5 – Catherine de ' Medici, queen of Henry II of France ( b. 1519 )
* July 6 – Edmund Grindal, Archbishop of Canterbury ( b. 1519 )
* November 21 – Thomas Gresham, English merchant and financier ( b. 1519 )
* February 24 – Francis, Duke of Guise, French soldier and politician ( shot ) ( b. 1519 )
* June 6 – Ikeda Nagamasa, Japanese military commander ( b. 1519 )
** Nicholas Grimald, English poet and theologian ( b. 1519 )
* July 10 – King Henry II of France ( jousting accident ) ( b. 1519 )
* July 15 – René of Châlon, Prince of the House of Orange ( b. 1519 )
Sir Jacobus van Meteren ( b. 1519, Breda ) was the financier and printer of early English versions of the Bible.
The Great Seal ( charter number 1519, confirmed at Holyroodhouse on 8 April 1588 ), gives James Maitland of Lethington ( b. 1568 ) as " son and heir of William Maitland of Lethington, Royal Secretary ".

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