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In a three-year-long study of metreleptin in patients with lipodystrophy organized by the National Institute of Diabetes and Digestive and Kidney Diseases ( NIDDK ) at the National Institutes of Health ( NIH ), metreleptin treatment was associated with a significant decrease in blood glucose ( A1c decrease from 9. 4 % at baseline to 7. 0 % at study end ) and triglyceride concentration ( from 500 mg / dL at baseline to 200 mg / dL at study end ).
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three-year-long and with
Bahram V arrived from Hira and captured the throne after defeating the Persian nobles with an Arab army in a three-year-long battle.
Elyot and Amanda, following a volatile three-year-long marriage, have been divorced for the past five years, but they now discover that they are sharing a terrace while on their honeymoons with their new and younger spouses.
" When Fawcett died on June 25, 2009, after her three-year-long battle with anal cancer, Majors issued a statement which read, " She fought a tremendous battle against a terrible disease.
In 2001, Argentina was in the midst of a crisis: heavily indebted, with an economy in complete stagnation ( an almost three-year-long recession ), and the exchange rate was fixed at one U. S. dollar per Argentine peso by law, which made exports uncompetitive and effectively deprived the state of having an independent monetary policy.
three-year-long and by
Network Rail did this, in spite of a three-year-long campaign by the town's people to save the gates, in order to improve performance and safety, and to reduce costs.
Troika Games officially began work on the game in November 2001, but the nearly three-year-long production cycle was plagued by many problems.
In the 18th century, the fort was taken over by the Maratha army under Peshwa Baji Rao's brother Chimaji Appa, and fell in 1739 after a three-year-long campaign.
three-year-long and at
The TMK-1 spacecraft was due to be launched in 1971 and make a three-year-long flight including a Mars flyby, at which time probes would have been dropped.
three-year-long and was
From this point it was a three-year-long struggle to acquire the land needed from forty-five property owners.
three-year-long and .
The three-year-long Azusa Street Revival in Los Angeles, California, resulted in the spread of Pentecostalism throughout the United States and the rest of the world as visitors carried the Pentecostal experience back to their home churches or felt called to the mission field.
It ended the three-year-long Carolingian Civil War.
In 1979 the EPA began a three-year-long feeding operation in order to increase the survival rate of kittens, but these actions have received some criticism.
The first phase of the center's three-year-long expansion and renovation is dedicated.
The tragic example of the three-year-long famine is the most forceful rebuttal of such a view.
: Kei is an 18-year-old who retains a 15-year-old body after a three-year-long " standstill ", which is a coma-like state that occurs during a time of extreme emotional distress.
study and metreleptin
The Juvenile Diabetes Research Foundation ( JDRF ) has also partnered with Amylin Pharmaceuticals and researchers at the University of Texas ( UT ) Southwestern Medical Center to study whether metreleptin can be used to improve the treatment of type 1 diabetes.
However in clinical trials, the study was halted at Phase 2 in 2011 when a problem involving antibody activity that might have neutralized the weight-loss effect of metreleptin in two patients who took the drug in a previously completed clinical study.
The study combined metreleptin, a version of the human hormone leptin, and pramlintide, which is Amylin ’ s diabetes drug Symlin, into a single obesity therapy.
study and patients
The study comprised 16 male patients, ranging in age from 27 to 72.
Whether this abnormal TSH differs chemically from pituitary TSH, or is, alternatively, normal TSH with its period of effectiveness modified by some other blood constituent, cannot be decided without chemical study of the activity in the blood of these patients and a comparison of the substance responsible for the blood activity with pituitary Aj.
Training likely needs to be intense and focused — as indicated by one study performed with stroke patients experiencing limb ataxia who underwent intensive upper limb retraining.
One study on respiratory tract infections found " physicians were more likely to prescribe antibiotics to patients who appeared to expect them ".
The study concluded that one-on-one lessons in the Alexander Technique from registered teachers have long term benefits for patients with chronic back pain, and that six lessons followed by exercise prescription were nearly as effective as 24 lessons.
A 1996 Tel Aviv hospital study of 67 patients with back pain of more than three months duration found patients benefited from a multidisciplinary approach to treatment that included back schooling, psychological intervention, and treatment by acupuncture, chiropractic, the Alexander Technique and a pain specialist.
The same study also found patients treated with SSRIs were 64 % more likely to achieve a 50 % absolute reduction in HRSD than patients given a placebo.
In a large clinical study, one of the agents in the ACE inhibitor class, ramipril ( Altace ), demonstrated an ability to reduce the mortality rates of patients who suffered a myocardial infarction, and to slow the subsequent development of heart failure.
While controlled clinical trials of atypicals reported that extrapyramidal symptoms occurred in 5 – 15 % of patients, a study of bipolar disorder in a real world clinical setting found a rate of 63 %, questioning the generalizability of the trials.
A study found that the patented method called Circulator Boot achieved significant results in prevention of amputation in patients of diabetes and arterioscleorosis.
Another study confirmed the seriousness of the disorder as " the standardized all-cause mortality ratio among patients with bipolar disorder is increased approximately two-fold.
Also, bioethicists may be concerned with the ethical implications of consciousness in medical cases of patients such as Karen Ann Quinlan, while neuroscientists may study patients with impaired consciousness in hopes of gaining information about how the brain works.
Placebo-controlled studies have found that AZT as a single agent produces modest and short-lived improvements in survival and delays the development of opportunistic infections ; it certainly did not cause AIDS, which develops in both treated and untreated study patients.
A negative study may reflect a lack of benefit, or simply a lack of sufficient quantities of patients to detect a difference.
Interestingly, these patients are often first diagnosed when they have their first generalized tonic-clonic seizure later in life, when they experience sleep deprivation ( e. g., freshman year in college after staying up late to study for exams ).
A study of patients with previously untreated epilepsy demonstrated that 47 % achieved control of seizures with the use of their first single drug.
In addition, there may be a link between ET and Parkinson's disease, with one study showing ET patients having an approximately 4 times greater likelihood of developing Parkinson's disease.
The study found that 36 percent of the cancer patients had HPV compared to only 1 percent of the healthy control group.
However another study, had observed that pusher syndrome is also present in patients with left hemisphere lesions, leading to aphasia, providing a stark contrast to what was previously believed regarding hemispatial neglect, which mostly occurs with a right hemisphere lesion.
Results from a study on patients with severe hemiparesis concluded that MT was successful in improving motor and sensory function of the distal hemiparetic upper limb.
Recent study confirm the fact that HDL has a buffering role in balancing the effects of hypercoagulable state in type 2 diabetics and decreases high risk of cardiovascular complications in these patients.
Public authorities should oppose laws which undermine natural law ; scientists should further study effective methods of natural birth control ; doctors should further familiarize themselves with this teaching, in order to be able to give advice to their patients, priests must spell out clearly and completely the Church's teaching on marriage.
study and with
Dr. Isaacs was so pleased with the quality of her biographical study of Sara Sullam that he considered submitting it to the Century Magazine or Harper's but he decided that its Jewish subject probably would not interest them and published it in The Messenger, `` so our readers will be benefited instead ''.
With her son evidencing so strong a musical bent his mother could do little else but get him started on the study of music -- though she waited until he was ten -- beginning with the piano and following that with the trumpet.
Arlen is one of the few ( possibly the only ) composer Mercer has been able to work with so closely, for they held their meetings in Arlen's study.
In much the same way, we recognize the importance of Shakespeare's familarity with Plutarch and Montaigne, of Shelley's study of Plato's dialogues, and of Coleridge's enthusiastic plundering of the writings of many philosophers and theologians from Plato to Schelling and William Godwin, through which so many abstract ideas were brought to the attention of English men of letters.
Criticism is as old as literary art and we can set the stage for our study of three moderns if we see how certain critics in the past have dealt with the ethical aspects of literature.
Michelangelo found the rabbi in the room of study, a gentle old man with a white beard and luminous grey eyes, robed in black gabardine with a skullcap on his head.
During the period from 1 July 1960 through 31 January 1961, additional research affiliations were effected with the U. S. Army Medical Research and Development Command to conduct research in procedures for quantitative electron microscopy, and for the study of biophysical and biological studies of the structure and function of ocular tissue.
Distribution costs are almost bound to increase in the sixties -- and you will never know what you can do to control them unless you study each element and experiment with alternative ways of doing the job.
The study of the radio emission of the moon and planets began with the detection of the thermal radiation of the moon at 1.25-cm wave length by Dicke and Beringer ( 1946 ).
Af appeared to be well suited for the study of these matters, since it is a normal paramagnet, with three unpaired electrons on the chromium, its crystal structure is very simple, and the unknown position of the hydrogen in the strong Af bond provides structural interest.
A study of their activity on thyroglobulin has shown that thyroxine is not preferentially released and that the degradation proceeds stepwise with the formation of macromolecular intermediates ( Alpers, Petermann and Rall, 1956 ).
If we try to study T using characteristic values, we are confronted with two problems.
For example, the level of improvement noted in a recent experiment with a short course of immediate treatment for parent-child relationship problems compared favorably with the results reported by typical child guidance clinics where the hours spent in purely diagnostic study may equal or exceed the number of hours devoted to actual treatment interviews in the experimental project.
The study of odd-lot indices is somehow akin to the spectacle of a man trying to outfox his own shadow, what with all observers trying to get on the side of the `` few '' at the same time.
There were two methods that could have been used for conducting the study within the resources available: ( 1 ) interviews in depth with a few selected companies, and ( 2 ) the more limited interrogation of a large number of companies by means of a mail questionnaire.
The second step in processing was to compare the responses from companies on the AIA list with those from companies on the TR list in order to determine whether it would be appropriate to merge the responses for the purposes of the study.
For example, he cites the following data from two studies on job satisfaction: in the first study, 85 per cent of professionals and executives, 64 per cent of white collar people, and 41 per cent of factory workers expressed satisfaction with their jobs ; ;
In another study chromium-substituted aluminum oxyhydroxides and related species, prepared homogeneously by high-temperature hydrolysis, are being characterized and investigated spectrally in the ultraviolet region with a view to identification and semiquantitative estimation of the phases formed under varying preparative conditions.
Yet, in spite of this, intensive study of the taped interviews by teams of psychotherapists and linguists laid bare the surprising fact that, in the first five minutes of an initial interview, the patient often reveals as many as a dozen times just what's wrong with him ; ;
New ideas for improving nutrition came with the study of soil treatment.
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