In contrast, Biopharmaceuticals are large biological molecules such as proteins that are developed to address targets that cannot easily be addressed by small molecules.

Carnivory was a natural transition from insectivory for medium and large tetrapods, requiring minimal adaptation ( in contrast, a complex set of adaptations was necessary for feeding on highly fibrous plant materials ).

In contrast, the United States Navy deployed its large carriers in separate formations, with each carrier assigned its own cruiser and destroyer escorts.

In contrast, though Oslo ( Norway ) and Stockholm ( Sweden ) are quite dominant in terms of speech standards, cities like Bergen, Gothenburg and the Malmö-Lund region are large and influential enough to create secondary regional norms, making the standard language more varied than is the case with Danish.

By contrast, integrated circuits packed a large number — often millions — of tiny electrical components, mainly transistors, into a small chip around the size of a coin.

By contrast, the Gemini capsule's avionics were designed so the cabin could be exposed to the vacuum of space when one of two large hatches was opened, so no airlock was required, and both the spacewalking astronaut and his companion command pilot were in vacuum during the EVA.

In contrast to his own diminutive stature, his personal assistant and secretary Eduard Hedvicek, who later played a significant role in the unsuccessful attempt to save his life was a very large and tall man ( 200 cm

By contrast, wholesale payments are generally for large-dollar amounts and often involve a depository institution's large corporate customers or counterparties, including other financial institutions.

By contrast, incurring large or long-term debts ( though sometimes unavoidable ) is viewed as often resulting from irresponsibility or self-indulgence.

In this report I shall call strongly interacting particles " hadrons ", and the corresponding decays " hadronic " ( the Greek ἁδρός signifies " large ", " massive ", in contrast to λεπτός which means " small ", " light ").

Along the horizon, the setting sun silhouettes the farm with its abundant stacks of grain, in contrast to the large shadowy figures in the foreground.

By contrast, the languages of Tanzania have large numbers of inflectional suffixes.

In any case, there are two large caveats to contrast ratio as a measure of LCD performance.

The teaching is Socratic, typically with small classes, and often boasts a lower student-to-teacher ratio than at large universities ; professors teaching classes are allowed to concentrate more on their teaching responsibilities than primary research professors or graduate student teaching assistants, in contrast to the instruction common in universities.

Despite the large number of philosophical schools and subtle nuances between many, all philosophies are said to fall into one of two primary categories, which are defined in contrast to each other: Idealism, and materialism.

In contrast, even relatively large stony or icy bodies like small comets or asteroids, up to millions of tons, are disrupted in the atmosphere, and do not make impact craters.

In contrast, the Roman army and Persian army at the time both had large numbers of heavy infantry and heavy cavalry ( cataphracts and clibanarii ) that were better equipped, heavily protected, and more experienced and disciplined.

Glyndŵr offered to release Mortimer for a large ransom but, in sharp contrast to his attitude to de Grey, Henry IV refused to pay.

In contrast, a propensitist is able to use the law of large numbers to explain the behaviour of long-run frequencies.

Hindgut fermenters, in contrast to the ruminants, store digested food which has left the stomach in a pouch-like extension of the large intestine called the cecum ( literally " cave "), where the food is digested by bacteria.

In contrast, the more advanced, large pterodactyloid pterosaurs such as Pteranodon grew to adult size within the first year of life.

In contrast, in the QCD they " fluctuate " ( annealing ), and through the large number of gauge degrees of freedom the entropy plays an important role ( see below ).

The contrast between parental and youth culture exemplified by rock and roll was a recurring source of concern for older generations, who worried about juvenile delinquency and social rebellion, particularly as to a large extent rock and roll culture was shared by different racial and social groups.

In contrast to a ball, a sphere may be an empty set, even for a large radius.

Amino acids that prefer to adopt helical conformations in proteins include methionine, alanine, leucine, glutamate and lysine (" MALEK " in amino-acid 1-letter codes ); by contrast, the large aromatic residues ( tryptophan, tyrosine and phenylalanine ) and-branched amino acids ( isoleucine, valine, and threonine ) prefer to adopt β-strand conformations.

As of 1987, he replaced the term " mass comparison " with " multilateral comparison ", to emphasize its contrast with the bilateral comparisons recommended in linguistics textbooks.

In contrast, objects with a very small mass, such as the electron, have wavelike characteristics which permit such an event, referred to as tunneling.

In contrast to the tonne as a mass unit, the tonne-force or metric ton-force is not acceptable for use with SI, partly because it is not an exact multiple of the SI unit of force, the newton.

In contrast to cargo-only chemical space gun concepts, a mass driver could be any length affordable, with relatively smooth acceleration throughout, optionally even lengthy enough to reach target velocity without excessive g forces for passengers.

World War II saw the beginning of a mass Māori migration to the cities, and by the 1980s 80 % of the Māori population was urban, in contrast to only 20 % before the war.

In contrast to this approximation, as particles approach the speed of light, their relativistic mass increases, requiring either modifications to the frequency, leading to the synchrocyclotron, or modifications to the magnetic field during the acceleration, which leads to the isochronous cyclotron.

A star like Deneb, for instance, has a radius that is 203, yielding a mass of 19 and luminosity of 196, 000, which means that this blue-white supergiant radiates one hundred and ninety-six thousand times as much energy as the Sun .< ref name =" SCHILLER1 "> By contrast, the much cooler Betelgeuse has a luminosity of approximately 120, 000, a figure which is only possible because it is considerably larger than Deneb ; with a radius of about 995, Betelgeuse is about 15 times its size.

Detection is here done by mass spectrometry, but in contrast to MALDI-MS with an electrospray ionisation ( ESI ) interface ( PGC-LC-ESI-MS or PGCC-MS )

In contrast, the cells of the inner cell mass restrict mtDNA replication until they receive the signals to differentiate to specific cell types.

By contrast, the laws of physics dictate that the operating mechanism of a semi-automatic weapon must increase in mass and weight as the cartridge it fires increases in power.

By contrast, American artists being bombarded daily with the diversity of mass produced imagery, produced work that was generally more bold and aggressive.

A 10 gigatesla field, by contrast, has an energy density of 4. 0 × 10 < sup > 25 </ sup > J / m < sup > 3 </ sup >, with an E / c < sup > 2 </ sup > mass density > 10 < sup > 4 </ sup > times that of lead.

For middle-weight nuclides this value is negative in contrast to the mass change which is never negative for any nuclide.

According to a Pew Research Center study, media coverage mostly emanated from the United States in 2002, when a Boston Globe series began a critical mass of news reports ; by contrast, in 2010 much of the reporting focused on child abuse in Europe.

In contrast to small rock falls, mass movements are less common.

In contrast to the Sun where convection only occurs in the outer layers, a red dwarf with a mass this low will be entirely convective.

In contrast to incompressible flows, which can usually be solved by considering only the equations from conservation of mass and conservation of momentum.

During this period, in contrast to the near-universal marketing technique of introducing innovations on the expensive side of the marketplace and relying on consumer demand to emulate early adopters along with economy of scale to bring them into the mass market, Shimano and SunTour ( to a lesser extent ) introduced new technologies at the lowest end of the bicycle market, using lower cost and often heavier and less durable materials and techniques, only moving them further upmarket if they established themselves in the lower market segments.

In contrast, as a submarine expels water from its buoyancy tanks, it rises because its volume is constant ( the volume of water it displaces if it is fully submerged ) while its mass is decreased.

By contrast, there is a widespread belief that violent crime is on the rise, due largely to a mass media which disproportionately reports violent crime.

A decree of Economic Stabilisation was introduced in 1959, opening the way for massive foreign investment-" a watershed in post-war economic, social and ideological normalisation leading to extraordinarily rapid economic growth ", that marked Spain's " participation in the Europe-wide post-war economic normality centred on mass consumption and consensus, in contrast to the concurrent reality of the Soviet bloc.

In contrast to Cepheids, RR Lyraes are old, relatively low mass, metal-poor " Population II " stars.

Through the mass distribution of particular shanty forms through recordings and clubs, the Folk Revival has had the effect of creating an impression of rather consistent forms of texts and tunes — a sharp contrast to the highly variable and often improvised nature of work-based shanty singing.

In contrast to most Western programmes of the time, much consideration was given to active, besides passive protection, to limit the overall mass of the vehicle.