First, is the circulating form of the hormone the same as that found in the gland where it is synthesised and stored??

For example the standard glutamic acid ( glutamate ) and the non-standard gamma-amino acid gamma-amino-butyric acid ( GABA ) are respectively the brain's main excitatory and inhibitory neurotransmitters, hydroxyproline-a major component of the connective tissue collagen-is synthesised from proline, the standard amino acid glycine is used to synthesise porphyrins used in red blood cells, and the non-standard carnitine is used in lipid transport.

This is synthesised intracellularly as tropocollagen and then exported, forming fibrils.

All known DNA replication systems require a free 3 ' OH group before synthesis can be initiated ( Important note: DNA is read in 3 ' to 5 ' direction whereas a new strand is synthesised in the 5 ' to 3 ' direction-this is entirely logical but is often confused ).

Thus Galen summarised and synthesised the work of his predecessors, and it is in Galen's words ( Galenism ) that Greek medicine was handed down to subsequent generations, such that Galenism became the means by which Greek medicine was known to the world.

Farbenindustrie AG at the Farbwerke Hoechst ( it is synthesised from 1, 1-diphenylbutane-2-sulfonic acid and dimethylamino-2-chloropropane ) who were looking for a synthetic opioid that could be created with readily available precursors, to solve Germany's opium shortage problem.

The modern legend that follows below is synthesised from early and late hagiographical sources, omitting the more fantastical episodes, to narrate a purely human military career in closer harmony with modern expectations of reality.

The biogenic silica that the cell wall is composed of is synthesised intracellularly by the polymerisation of silicic acid monomers.

SEC can be used as a measure of both the size and the polydispersity of a synthesised polymer, that is, the ability to be able to find the distribution of the sizes of polymer molecules.

Also unlike DNA replication where DNA is synthesised, transcription does not involve an RNA primer to initiate RNA synthesis.

One major function of chaperones is to prevent both newly synthesised polypeptide chains and assembled subunits from aggregating into nonfunctional structures.

Due to the way that glycogen is synthesised, every glycogen granule has at its core a glycogenin protein.

In 1958, the first beta blocker, dichloroisoproterenol, was synthesised by Eli Lilly Laboratories, but Sir James W. Black in 1962, found the first clinically significant beta blockers-propranolol and pronethalol ; it revolutionized the medical management of angina pectoris and is considered by many to be one of the most important contributions to clinical medicine and pharmacology of the 20th century.

However, it is present in red algae, which seems to suggest that the common ancestor of plants and red algae also synthesised lignin.

Fibrinogen ( factor I ) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation.

Fibrinogen is a 340 kDa glycoprotein synthesised in the liver by hepatocytes.

) An alternate meaning is simply " 13th Room Kata ", being the form synthesised in the 13th room of Shaolin, using individual techniques taught in the previous training rooms.

Even the knowledge that she was losing another boy, as a mother always does when a marriage is made, did not prevent her from having the first carefree, dreamless sleep that she had known since they dropped down the canyon and into Bear Valley, way, way back there when they were crossing those other mountains.

Bryn Mawr Drive is only two or three miles from the Spartan, and it took me less than five minutes to get there.

The true artist is like one of those scientists who, from a single bone can reconstruct an animal's entire body.

This is puzzling to an outsider conscious of the classic tradition of liberalism, because it is clear that these Democrats who are left-of-center are at opposite poles from the liberal Jefferson, who held that the best government was the least government.

But apart from racial problems, the old unreconstructed South -- to use the moderate words favored by Mr. Thomas Griffith -- finds itself unsympathetic to most of what is different about the civilization of the North.

The Bourbon economic philosophy, moreover, is not very different from that of Northern conservatives.

It is noteworthy that the majority of the delegates to the Congress were from the less developed, former colonial nations.

Today, as new nations rise from the former colonial empires, nationalism is one of the hurricane forces loose in the world.

To him, law is the command of the sovereign ( the English monarch ) who personifies the power of the nation, while sovereignty is the power to make law -- i.e., to prevail over internal groups and to be free from the commands of other sovereigns in other nations.

And Bill Wisman, forty-three, a farmer's son from Beallsville, Ohio, is a quiet but impressive man.

In point of fact, this is a beige box with a bright red door, about one and a half feet square and hung from the wall about six feet from the door to Wisman's right.

from downstream, where the water level is much lower, it is a high, elaborately facaded pavilion.

Here, on the hottest day, it is cool beneath the stone and fresh from the water flowing in the sluices at the bottom of the vaults.

Since it is not far from Viareggio, he will visit Puccini's house, as he never fails to do, to pay his respects to the memory of the composer of La Boheme, which he considers one of Puccini's masterpieces.

`` I have just come from viewing a man who had made the fortune of his country, but now is working all night in order to support his family '', he reflected.

It is interesting, however, that despite this strong upsurge in Southern writing, almost none of the writers has forsaken the firmly entrenched concept of the white-suited big-daddy colonel sipping a mint julep as he silently recounts the revenue from the season's cotton and tobacco crops ; ;

A new South is emerging after the post-bellum years of hesitation, uncertainty, and lack of action from the Negro in defining his new role in the amorphously defined socio-political organizations of the white man.

If his dancers are sometimes made to look as if they might be creatures from Mars, this is consistent with his intention of placing them in the orbit of another world, a world in which they are freed of their pedestrian identities.

Though he is also concerned with freeing dance from pedestrian modes of activity, Merce Cunningham has selected a very different method for achieving his aim.

The fact is that the Southern Confederacy differed from the earlier one almost as much as the Federal Constitution did.

For the family is the simplest example of just such a unit, composed of people, which gives us both some immunity from, and a way of dealing with, other people.

The approximate amino acid composition of gelatin is: glycine 21 %, proline 12 %, hydroxyproline 12 %, glutamic acid 10 %, alanine 9 %, arginine 8 %, aspartic acid 6 %, lysine 4 %, serine 4 %, leucine 3 %, valine 2 %, phenylalanine 2 %, threonine 2 %, isoleucine 1 %, hydroxylysine 1 %, methionine and histidine < 1 % and tyrosine < 0. 5 %.

An example of a mutation in P53 is where arginine 248 is altered, sometimes causing a disruption in balance and making the protein unable to bind with the DNA.

Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline.

The aspartate residue ( Asp 189 ) located in the catalytic pocket ( S1 ) of trypsins is responsible for attracting and stabilizing positively charged lysine and / or arginine, and is, thus, responsible for the specificity of the enzyme.

This means that trypsin predominantly cleaves proteins at the carboxyl side ( or " C-terminal side ") of the amino acids lysine and arginine except when either is bound to a N-terminal proline., although large-scale mass spectrometry data suggest cleavage occurs even with proline.

The most common type in humans is central DI, caused by a deficiency of arginine vasopressin ( AVP ), also known as antidiuretic hormone ( ADH ).

* Antidiuretic hormone ( ADH, also known as vasopressin and AVP, arginine vasopressin ), the majority of which is released from the supraoptic nucleus in the hypothalamus

For instance, in Western populations the H1069Q mutation ( replacement of a histidine by a glutamine at position 1069 in the protein ) is present in 37 – 63 % of cases, while in China this mutation is very uncommon and R778L ( arginine to leucine at 778 ) is found more often.

Lysine is a base, as are arginine and histidine.

It is assumed to be an antimetabolite of arginine.

Renin-angiotensin axis is activated and arginine vasopressin ( Anti-diuretic hormone ; ADH ) is released to conserve fluid via the kidneys.

Although the exact mechanism of the event is unknown, key amino acid residues identified include tyrosine at positions 80 and 123, glutamic acid at position 177, and arginine at position 180.

The isoelectric point of a given protein is determined by the relative number of positively ( e. g. lysine and arginine ) and negatively ( e. g. glutamate and aspartate ) charged amino acids, with negatively charged amino acids contributing to a high isoelectric point and positively charged amino acids contributing to a low isoelectric point.

Desmopressin is used to improve platelet function by activating arginine vasopressin receptor 1A.

In plants and microbes, OTC is involved in arginine ( Arg ) biosynthesis, whereas in mammals it is located in the mitochondria and is part of the urea cycle.

The ar / R ( aromatic / arginine ) selectivity filter is a cluster of amino acids that help bind to water molecules and exclude other molecules that may try to enter the pore.

For instance, a hydrophilic residue such as arginine is more likely to be replaced another hydrophilic residue such as glutamine, than it is to be mutated into a hydrophobic residue such as leucine.