Lorazepam is the only benzodiazepine with predictable intramuscular absorption and it is the most effective in preventing and controlling acute seizures.

Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect.

Lorazepam is most commonly used but clonazepam is sometimes prescribed for acute psychosis or mania ; their long-term use is not recommended due to risks of dependence.

Lorazepam ( Ativan ) is often used and is a sedative which has no effect on the disease process rather helps patients cope with the sensation.

Lorazepam ( initially marketed under the brand names Ativan and Temesta ) is a high-potency, short-to intermediate-acting, 3-hydroxy benzodiazepine drug that has all six intrinsic benzodiazepine effects: anxiolytic, amnesic, sedative / hypnotic, anticonvulsant, antiemetic and muscle relaxant.

Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus and sedation of hospitalized patients, as well as sedation of aggressive patients.

Lorazepam is considered to be a short-acting drug which, similar to other benzodiazepines, exerts its therapeutic, as well as adverse, effects via its interaction at benzodiazepine binding sites, which are located on GABA < sub > A </ sub > receptors in the central nervous system.

Lorazepam impairs body balance and standing steadiness and is associated with falls and hip fractures in the elderly.

Lorazepam has relatively potent anxiolytic effects and its best-known indication is the short-term management of severe anxiety ; the FDA advises against use of benzodiazepines such as lorazepam for longer than two to four weeks.

Lorazepam is sometimes used for individuals receiving mechanical ventilation.

Lorazepam is sometimes used as an alternative to midazolam in palliative sedation.

Lorazepam is more effective than diazepam in the treatment of status epilepticus.

Lorazepam is sometimes used as an alternative to haloperidol when there is the need for rapid sedation of violent or agitated individuals, but haloperidol plus promethazine is preferred due to better effectiveness and due to lorazepam's adverse effects on respiratory function.

Lorazepam is absorbed relatively slowly if given intramuscularly, a common route in restraint situations.

Lorazepam is also used to treat acute symptoms of vertigo and dizziness for people with Ménière's disease.

Lorazepam injectable solution is administered either by deep intramuscular injection or by intravenous injection.

* Pregnancy and breast feeding – Lorazepam belongs to the Food and Drug Administration ( FDA ) pregnancy category D, which means it is likely to cause harm to the developing baby, if taken during the first trimester of pregnancy.

Lorazepam is not usually fatal in overdose, but may cause fatal respiratory depression if taken in overdose with alcohol.

** Lorazepam said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine or Zofran.

Lorazepam should, therefore, not be prescribed in high doses or as the sole treatment in depression, but only with an appropriate antidepressant.

Lorazepam should be avoided in people with:

Lorazepam may also be slower to clear in the elderly, leading potentially to accumulation and enhanced effects.

* Liver or kidney failure – Lorazepam may be safer than most benzodiazepines in patients with impaired liver function.

Lorazepam may be quantitated in blood or plasma to confirm a diagnosis of poisoning in hospitalized patients, provide evidence in an impaired driving arrest or to assist in a medicolegal death investigation.

If treatment has to be stopped at once due to medical reasons, the use of a benzodiazepine ( e. g. Lorazepam, Clonazepam, or Alprazolam ) for a maximum of 4 weeks as needed will usually suppress withdrawal symptoms.

Recent excavation of garbage dumps adjacent to the brothels has revealed opium bottles, prescription tranquilizers similar to Lorazepam, champagne bottles, and pickle jars.

Lorazepam also has abuse potential ; the main types of misuse are for recreational purposes or continued use against medical advice.

Lorazepam has strong sedative / hypnotic effects, and the duration of clinical effects from a single dose makes it an appropriate choice for the short-term treatment of insomnia, in particular in the presence of severe anxiety.

Lorazepam tablets and syrups are administered by mouth only.

Lorazepam appears to have more profound adverse effects on memory than other benzodiazepines ; it impairs both explicit and implicit memory.

* Acute intoxication – Lorazepam may interact synergistically with the effects of alcohol, narcotics, or other psychoactive substances.

* Acute narrow-angle glaucoma – Lorazepam has pupil-dilating effects, which may further interfere with the drainage of aqueous humour from the anterior chamber of the eye, thus worsening narrow-angle glaucoma.

The enormous changes in world politics have, however, thrown it into confusion, so much so that it is safe to say that all international law is now in need of reexamination and clarification in light of the social conditions of the present era.

While sovereignty has roots in antiquity, in its present usage it is essentially modern.

Everyone is ready to grant the Persians their history, but almost no one is willing to acknowledge their present.

It is said that, even at the present stage of Southern urbanization, such a city as Atlanta is not distinctly unlike Columbus or Trenton.

This almost trivial example is nevertheless suggestive, for there are some elements in common between the antique fear that the days would get shorter and shorter and our present fear of war.

Harold Clurman is right to say that `` Waiting For Godot '' is a reflection ( he calls it a distorted reflection ) `` of the impasse and disarray of Europe's present politics, ethic, and common way of life ''.

The beatnik, seceding from a society that is fatally afflicted with a deathward drive, is concerned with his personal salvation in the living present.

For the present it is enough to note that in the grotesque figure of Jacoby, at the moment of his collapse, all these elements come together in prophetic parody.

So it is that we relive his opening statement in the first television address with the dramatic immediacy of the present.

The problem is rather to find out what is actually happening, and this is especially difficult for the reason that `` we are busily being defended from a knowledge of the present, sometimes by the very agencies -- our educational system, our mass media, our statesmen -- on which we have had to rely most heavily for understanding of ourselves ''.

Going back over this ground and analyzing the composition of forces which have created the present scene is one of the tasks undertaken by the Center for the Study of Democratic Institutions, in Santa Barbara.

But however we come, finally, to explain and account for the present, the truth we are trying to expose, right now, is that the makers of constitutions and the designers of institutions find it difficult if not impossible to anticipate the behavior of the host of all their enterprises.

and the laughter and the happiness are even more pronounced when no company is present.

I am assured by experts that the thrust of our present missiles is fully adequate for defense requirements.

Steele's purpose is to present a general defense of his political writing and a resume of the themes which had occupied him in the Englishman ; ;

Undoubtedly one merit of the vast panorama of Gentile conceptions of the Jew unfolded in the present anthology is that it provides a formidable body of material that invites critical examination in terms of reality.

Properly used, the present book is an excellent instrument of enlightenment.

The continuities, contrasts, and similarities discernible when past and present are surveyed together are inexhaustible and the one is often understood through the other.