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Morvan ’ s Syndrome, or Morvan ’ s fibrillary chorea ( MFC ), is a rare autoimmune disease named after nineteenth century French physician Augustin Marie Morvan.
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Morvan and ’
There are only about 14 reported cases of Morvan ’ s Syndrome in the English Literature.
The natural history of Morvan ’ s is highly variable.
Antibodies against voltage-gated potassium channels ( VGKC ), which are detectable in about 40 % of patients with acquired neuromytonia, have been implicated in Morvan ’ s pathophysiology.
Raised serum levels of antibodies to VGKCs have been reported in three patients with Morvan ’ s Syndrome.
Binding of serum from a patient with Morvan ’ s Syndrome to the hippocampus in a similar pattern of antibodies to known VGKC suggest that these antibodies can also cause CNS dysfunction.
It is believed that antibodies to the Shaker-type K + channels ( the Kv1 family ) are the type of potassium channel most strongly associated with acquired neuromyotonia and Morvan ’ s Syndrome.
Plasmapheresis alone or in combination with steroids, sometimes also with thymectomy and azathioprine, have been the most frequently used therapeutic approach in treating Morvan ’ s Syndrome.
Although thymectomy is believed to be a key element in the proposed treatment, there is a reported case of Morvan ’ s Syndrome presenting itself post-thymectomy.
In one case, a patient was diagnosed with both Morvan ’ s Syndrome and Pulmonary Hyalinizing Granulomas ( PHG ).
Thymoma, prostate adenoma, and in situ carcinoma of the sigmoid colon have also been found in patients with Morvan ’ s Syndrome.
The symptoms of Morvan ’ s Syndrome have been noted to bear a striking similarity to limbic encephalitis ( LE ).
Recently, VGKC antibodies were found in patients with LE, strengthening the hypothesis that LE and Morvan ’ s Syndrome may be closely connected.
Amnesia, seizures, and mesial temporal lobe structural abnormalities are features of LE, whereas myokymia, hyperhydrosis, and insomnia favor Morvan ’ s Syndrome.
Morvan and fibrillary
Patients display a remarkable hallucinatory behavior, and peculiar motor disturbances, which Morvan reported under the term “ fibrillary chorea ” but which are best described nowadays as neuromyotonic discharges.
Morvan and ),
* Le Morvan, Pierre ( 2005 ) " A Metaphilosophical Dilemma for Epistemic Externalism ", Metaphilosophy 36 ( 5 ), pp. 688 – 707.
* Le Morvan, Pierre ( 2004 ), " Ramsey on Truth and Truth on Ramsey ", British Journal for the History of Philosophy, 12 ( 4 ) 2004, 705 – 718, PDF.
His most ambitious canvases are Springtime ( 1857 ), in the Louvre ; Borde de la Cure, Morvan ( 1864 ); Villerville sur Mer ( 1864 ); Moonlight ( 1865 ); Auvers-sur-Oise ( 1868 ); and Return of the Flock ( 1878 ).
In 1989, Arista signed a German-based duo named Milli Vanilli, consisting of Rob Pilatus and Fabrice Morvan, and released its wildly successful multi-platinum debut album ( which had been previously released in Europe the year before ), Girl You Know It's True, the same year in the U. S. and Canada.
There is a French comic adaptation in 8 volumes of the books by Li-An ( drawings ) and Jean-David Morvan ( story ), published by Delcourt from 1998 to 2008.
* Le Morvan, Pierre ( 2004 ), " Ramsey on Truth and Truth on Ramsey ", British Journal for the History of Philosophy 12 ( 4 ), 705 – 718.
Morvan and is
Le Morvan advocates a third approach — he dubs it the " Health Approach "-- that explores when skepticism is healthy and when it is not, or when it is virtuous and when it is vicious.
Morvan ( 2004 ) argues that such a shared ontology is fatal for direct realism.
Located in northeast France, the Chablis region is considered the northernmost extension of the Burgundy wine region but it is separated from the Côte d ' Or by the Morvan hills, with the main Burgundian winemaking town of Beaune located more than away.
Its source is in the Nièvre département, in the Morvan hills near Château-Chinon.
The theory is commonly attributed to Frank P. Ramsey, who argued that the use of words like fact and truth was nothing but a roundabout way of asserting a proposition, and that treating these words as separate problems in isolation from judgment was merely a " linguistic muddle ", though there remains some debate as to the correct interpretation of his position ( Le Morvan 2004 ).
The massif Centale is represented locally by its northern extension, the Morvan, which lies between Nevers and the Côte d ' Or.
The entire cote is located along a fault line situated between the plains of the Saône and the Morvan hills to the west.
Morvan and named
It was named after the colours of the flag of Brittany, designed by Morvan Marchal in 1925.
Morvan and after
Months after the scandal, Pilatus and Morvan appeared in a commercial for Carefree sugarless chewing gum.
Morvan and French
* Northeast Caucasian languages, such as Chechen, are seen by the French linguist Michel Morvan as more likely candidates for a very distant connection.
* Wake ( comics ) comics, a French comic in book collection format created by Morvan and Buchet
Morvan and .
Pierre Le Morvan ( 2011 ) has distinguished between three broad philosophical approaches to skepticism.
* Le Morvan, P., " Healthy Skepticism and Practical Wisdom ," Logos & Episteme II, 1 ( 2011 ): 87-102.
“ La chorée fibrillaire ” was first coined by Morvan in 1890 when describing patients with multiple, irregular contractions of the long muscles, cramping, weakness, pruritus, hyperhidrosis, insomnia, and delirium.
In 1890, Morvan described a patient with myokymia ( muscle twitching ) associated with muscle pain, excessive sweating, and disordered sleep.
Other fatalities without remission have been described by, amongst others, Morvan himself.
’ and s
The AMPAS was originally conceived by Metro-Goldwyn-Mayer studio boss Louis B. Mayer as a professional honorary organization to help improve the film industry ’ s image and help mediate labor disputes.
The International Encyclopedia of the Social Sciences defines psychological altruism as " a motivational state with the goal of increasing another ’ s welfare ".
Psychological altruism is contrasted with psychological egoism, which refers to the motivation to increase one ’ s own welfare.
One way is a sincere expression of Christian love, " motivated by a powerful feeling of security, strength, and inner salvation, of the invincible fullness of one ’ s own life and existence ".
Another way is merely " one of the many modern substitutes for love, ... nothing but the urge to turn away from oneself and to lose oneself in other people ’ s business.
* David Firestone-When Romney ’ s Reach Exceeds His Grasp-Mitt Romney quotes the song
" Swift extends the metaphor to get in a few jibes at England ’ s mistreatment of Ireland, noting that " For this kind of commodity will not bear exportation, and flesh being of too tender a consistence, to admit a long continuance in salt, although perhaps I could name a country, which would be glad to eat up our whole nation without it.
George Wittkowsky argued that Swift ’ s main target in A Modest Proposal was not the conditions in Ireland, but rather the can-do spirit of the times that led people to devise a number of illogical schemes that would purportedly solve social and economic ills.
In response, Swift ’ s Modest Proposal was " a burlesque of projects concerning the poor ", that were in vogue during the early 18th century.
Critics differ about Swift ’ s intentions in using this faux-mathematical philosophy.
Charles K. Smith argues that Swift ’ s rhetorical style persuades the reader to detest the speaker and pity the Irish.
Swift ’ s specific strategy is twofold, using a " trap " to create sympathy for the Irish and a dislike of the narrator who, in the span of one sentence, " details vividly and with rhetorical emphasis the grinding poverty " but feels emotion solely for members of his own class.
Swift ’ s use of gripping details of poverty and his narrator ’ s cool approach towards them create " two opposing points of view " that " alienate the reader, perhaps unconsciously, from a narrator who can view with ' melancholy ' detachment a subject that Swift has directed us, rhetorically, to see in a much less detached way.
Once the children have been commodified, Swift ’ s rhetoric can easily turn " people into animals, then meat, and from meat, logically, into tonnage worth a price per pound ".
Swift uses the proposer ’ s serious tone to highlight the absurdity of his proposal.
In making his argument, the speaker uses the conventional, text book approved order of argument from Swift ’ s time ( which was derived from the Latin rhetorician Quintilian ).
James Johnson argued that A Modest Proposal was largely influenced and inspired by Tertullian ’ s Apology: a satirical attack against early Roman persecution of Christianity.
Johnson notes Swift ’ s obvious affinity for Tertullian and the bold stylistic and structural similarities between the works A Modest Proposal and Apology.
He reminds readers that " there is a gap between the narrator ’ s meaning and the text ’ s, and that a moral-political argument is being carried out by means of parody ".
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