NO activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate ( cGMP ), leading to smooth muscle relaxation in blood vessels supplying the corpus cavernosum, resulting in increased blood flow and an erection.

Soluble guanylate cyclase contains a molecule of heme, and is primarily activated by the binding of nitric oxide ( NO ) to that heme ).

Soluble guanylate cyclase ( sGC ) is the intracellular receptor for NO.

The primary receiver for NO produced by eNOS and nNOS is soluble guanylate cyclase, but many secondary targets have been identified.

It is synthesised from arginine and oxygen by the NO synthase and works through activation of soluble guanylyl cyclase, which when activated produces another second messenger, cGMP.

Besides the oxygen ligand, which binds to hemoglobin in a cooperative manner, hemoglobin ligands also include competitive inhibitors such as carbon monoxide ( CO ) and allosteric ligands such as carbon dioxide ( CO < sub > 2 </ sub >) and nitric oxide ( NO ).

Stimulation of the penile shaft by the nervous system leads to the secretion of nitric oxide ( NO ), which causes the relaxation of smooth muscles of corpora cavernosa ( the main erectile tissue of penis ), and subsequently penile erection.

Neptunium, like protactinium, uranium, plutonium, and americium readily forms a linear dioxo neptunyl core ( NpO < sub > 2 </ sub >< sup > n +</ sup >), in its 5 + and 6 + oxidation states, which readily complexes with hard O-donor ligands such as OH < sup >–</ sup >, NO < sub > 2 </ sub >< sup >–</ sup >, NO < sub > 3 </ sub >< sup >–</ sup >, and SO < sub > 4 </ sub >< sup > 2 –</ sup > to form soluble anionic complexes which tend to be readily mobile with low affinities to soil.

NO contacts can also be distinguished as " early-make " or NOEM, which means that the contacts will close before the button or switch is fully engaged.

One of the most active areas of solid propellant research is the development of high-energy, minimum-signature propellant using CL-20 ( China Lake compound # 20 ), C < sub > 6 </ sub > H < sub > 6 </ sub > N < sub > 6 </ sub >( NO < sub > 2 </ sub >)< sub > 6 </ sub >, which has 14 % higher energy per mass and 20 % higher energy density than HMX.

Ozone can be destroyed by a number of free radical catalysts, the most important of which are the hydroxyl radical ( OH ·), the nitric oxide radical ( NO ·), the atomic chlorine ion ( Cl ·) and the atomic bromine ion ( Br ·).

# Combustion of fossil fuels: automobile engines and thermal power plants, which release various nitrogen oxides ( NO < sub > x </ sub >).

In the primary stage of nitrification, the oxidation of ammonium ( NH < sub > 4 </ sub >< sup >+</ sup >) is performed by bacteria such as the Nitrosomonas species, which converts ammonia to nitrites ( NO < sub > 2 </ sub >< sup >-</ sup >).

Another inscription from Vindolanda on Hadrian's Wall reads " DEO NO / NEPTU ", which has been interpreted as " To the god Neptune Nodons ".

The overall increase in calcium triggers a massive release of cyt c, which then acts in the positive feedback loop to maintain ER calcium release through the IP3Rs ( Boehning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH.

A second major effect of isoprene on the atmosphere is that in presence of nitric oxides ( NO < sub > x </ sub >) it contributes to the formation of tropospheric ( lower atmosphere ) ozone, which is one of the leading air pollutants in many countries.

Formation of tropospheric ozone is only possible in presence of high levels of NO < sub > x </ sub >, which comes almost exclusively from industrial activities.

In contrast nitroxylation of 1 with nitric acid gives the apical nitrate 4 as an intermediate which is hydrolyzed to the apical alcohol 5 due to the higher steric demand of the active electrophilic NO < sub > 2 </ sub >-HNO < sub > 3 </ sub >< sup >+</ sup > species.

A 2005 study by Michael F. Hammer reports genetic similarities between the Japanese and several other Asian populations, which shows that the common Y-DNA haplogroups of Japanese are D-P37. 1 ( 34. 7 %), O-P31 ( 31. 7 %), O-M122 ( 20. 1 %), C-M8 ( 5. 4 %), C-M217 ( 3. 1 %), NO ( 2. 3 %) and N ( 1. 5 %).

He has a single hair sticking up on his head, a squint in one eye ( which also occasionally twitches ) and wears a shirt that says " NO.

Peroxy radicals then go on to react with NO to give NO < sub > 2 </ sub > which is photolysed to give atomic oxygen and through reaction with oxygen a molecule of ozone:

The county numbers are from the official numbering system ISO 3166-2: NO, which follows the coastline from the Swedish border in the southeast to the Russian border in the northeast.

ISO 3166-2: NO is the entry for Norway in ISO 3166-2, part of the ISO 3166 standard published by the International Organization for Standardization ( ISO ), which defines codes for the names of the principal subdivisions ( e. g., provinces or states ) of all countries coded in ISO 3166-1.

The patents covering this record, and under which it is made, among others, are U. S. patents NO 534, 543, dated Feb. 19, 1895, NO 548, 623 dated Oct 29, 1895 ...

Dilution, binding of histamine and increase in pH ( from pH ~ 5 in salivary gland to pH ~ 7. 4 in the host tissue ) facilitate the release of NO into the tissue where it induces vasodilatation.

This response is mediated by the release of nitric oxide ( NO ) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells.

Arginase II is coexpressed with nitric oxide ( NO ) synthase in smooth muscle tissue, such as the muscle in the genitals of both men and women.

The contraction and relaxation of these muscles has been attributed to NO synthase, which causes rapid relaxation of smooth muscle tissue and facilitates engorgement of tissue necessary for normal sexual response.

However, since NO synthase and arginase compete for the same substrate ( L-arginine ), over-expressed arginase can affect NO synthase activity and NO-dependent smooth muscle relaxation by depleting the substrate pool of L-arginine that would otherwise be available to NO synthase.

R. rosea promotes the release of NO from rat penile corpus cavernosum smooth muscle cell and artery endothelium cell, which was correlated with its effect to resist senility.

Normally endothelial cells release prostacyclin and nitric oxide ( NO ) which induce relaxation of the smooth muscle cells, and reduce aggregation of platelets.

It does not stimulate as much prostacyclin and NO to induce relaxation on smooth muscle cells.

The overall goal of the Acid Rain Program established by the Act is to achieve significant environmental and public health benefits through reductions in emissions of sulfur dioxide ( SO < sub > 2 </ sub >) and nitrogen oxides ( NO < sub > x </ sub >), the primary causes of acid rain.

Hydrochloric acid, sulfuric acid and nitric acid dissolve cadmium by forming cadmium chloride ( CdCl < sub > 2 </ sub >), cadmium sulfate ( CdSO < sub > 4 </ sub >), or cadmium nitrate ( Cd ( NO < sub > 3 </ sub >)< sub > 2 </ sub >).

* Voted NO on paying for AMT relief by closing offshore business loopholes.

* Voted NO on increasing AMTRAK funding by adding $ 214M to $ 900M.

NO: add string for local code followed by copy of its own first byte

NO is not released in the cytoplasm of erythrocytes but transported by an anion exchanger called AE1 out of them.

“ But I will have mercy upon the house of Judah, and will save them by the Lord their God, and will not save them by bow, nor by sword, nor by battle, by horses, nor by horsemen .”- Hosea 1: 7 in his sermon NO.

Solutions of salts such as BeCl < sub > 2 </ sub > or Al ( NO < sub > 3 </ sub >)< sub > 3 </ sub > in water are noticeably acidic ; the hydrolysis can be suppressed by adding an acid such as nitric acid, making the solution more acidic.

Ozone is not emitted directly ; rather, it is a secondary air pollutant, produced in the atmosphere by the reaction of NO < sub >" x "</ sub > and volatile organic compounds in the presence of sunlight.

This is because both YES and NO answers can be verified in polynomial time given the prime factors ( we can verify their primality using the AKS primality test, and that their product is N by multiplication ).

Single ions, such as synaptically released zinc, are also considered neurotransmitters by some, as are some gaseous molecules such as nitric oxide ( NO ), hydrogen sulfide ( H < sub > 2 </ sub > S ), and carbon monoxide ( CO ).

The NO is recycled, and the acid is concentrated to the required strength by distillation.

The ozone layer can be depleted by free radical catalysts, including nitric oxide ( NO ), nitrous oxide ( N < sub > 2 </ sub > O ), hydroxyl ( OH ), atomic chlorine ( Cl ), and atomic bromine ( Br ).

EURENCO Bofors ( of Bofors cannon fame ) by dissolving 65 % ammonium dinitramide, NH < sub > 4 </ sub > N ( NO < sub > 2 </ sub >)< sub > 2 </ sub >, in 35 % water solution of methanol and ammonia produced LMP-103S monopropellant as a 1-to-1 substitute for hydrazine.

The plant also installed low-NO < sub > x </ sub > SOFA burners in 2009-2011, reducing emissions of NO < sub > x </ sub >, a nitrate precursor, by 40 %.

One of Asprin ’ s last projects was NO Quarter, originally co-authored with Eric Del Carlo, and later edited by Teresa Patterson.

NO Quarter was published November 2009 by DarkStar Books.