Human diseases where dysmyelination has been implicated include leukodystrophies ( Pelizaeus – Merzbacher disease, Canavan disease, phenylketonuria ) and schizophrenia.

Normal looking at birth and for the first few years, hypotonic ( floppy ), in particular difficulty to hold the head, possibly difficulty to thrive, possibly with delayed myelination ( if so, some cases are reported with an MRI pattern similar to Pelizaeus – Merzbacher disease, known as PMD ,) possibly with decreased mitochondrial enzyme activities, possibly with fluctuating lactate level.

The onset of Pelizaeus – Merzbacher disease is usually in early infancy.

The prognosis for those with Pelizaeus – Merzbacher disease is highly variable, with children with the most severe form ( so-called connatal ) usually not surviving to adolescence, but survival into the sixth or even seventh decades is possible, especially with attentive care.

# REDIRECT Pelizaeus – Merzbacher disease

* Eugen Merzbacher – 1992

* Aortic aneurysm – myotic, bacterial ( e. g. syphilis ), senile, genetic, associated with valvular heart disease

* 1906 – Auguste Deter, the first person to be diagnosed with Alzheimer's disease, dies.

* 1990 – Gruinard Island, Scotland, is officially declared free of the anthrax disease after 48 years of quarantine.

Unconnected with inter-human wars, humans have deliberately introduced the rabbit disease Myxomatosis, originating in South America, to Australia and Europe, with the intention of reducing the rabbit population – which had devastating but temporary results, with wild rabbit populations reduced to a fraction of their former size but survivors developing immunity and increasing again.

There is some controversy over the identity of the disease, but in its virulent form, after the Great Plague of Marseille in 1720 – 1722, the Great Plague of 1738 ( which hit Eastern Europe ), and the Russian plague of 1770-1772, it seems to have gradually disappeared from Europe.

# REDIRECT Creutzfeldt – Jakob disease

Creutzfeldt – Jakob disease ( ) or CJD is a degenerative neurological disorder ( brain disease ) that is incurable and invariably fatal.

CJD is at times called a human form of mad cow disease ( bovine spongiform encephalopathy or BSE ) even though classic CJD is not related to BSE ; however, given that BSE is believed to be the cause of variant Creutzfeldt – Jakob ( vCJD ) disease in humans, the two are often confused.

Other prion diseases include Gerstmann – Sträussler – Scheinker syndrome ( GSS ), fatal familial insomnia ( FFI ) and kuru in humans, as well as bovine spongiform encephalopathy ( BSE, commonly known as mad cow disease ) in cattle, chronic wasting disease ( CWD ) in elk and deer, and scrapie in sheep.

The disease has also been shown to result from use of Human Growth Hormone obtained from the pituitary glands of persons who died from Creutzfeldt – Jakob Disease, though the known incidence of this cause is ( as of April 2004 ) quite small.

In the U. S., the FDA has banned import of any donor sperm, motivated by a risk of Creutzfeldt – Jakob disease, inhibiting the once popular import of, for example, Scandinavian sperm.

For example, the foot-and-mouth disease virus capsid has faces consisting of three proteins named VP1 – 3.

This teaching is the foundation of the Christian Science principle that disease – and any other adversity – can be cured through prayerful efforts, made possible only by God's grace, to fully understand this spiritual relationship.

After 4 – 8 weeks, individuals with active infections enter the chronic phase of Chagas disease that is asymptomatic for 60 – 80 % of chronically infected individuals through their lifetime.

The antiparasitic treatments also appear to delay or prevent the development of disease symptoms during the chronic phase of the disease, but 20 – 40 % of chronically infected individuals will still eventually develop life-threatening heart and digestive system disorders.

Of individuals with chronic Chagas disease, 60 – 80 % will never develop symptoms ( called indeterminate chronic Chagas disease ), while the remaining 20 – 40 % will develop life-threatening heart and / or digestive disorders during their lifetime ( called determinate chronic Chagas disease ).

* 1968 – PMD, American rapper ( EPMD

The Copy / Paste Detector ( CPD ) is an add-on to PMD that uses the Rabin – Karp string search algorithm to find duplicated code.

However implausible this is, it is certainly the case that Aristotle's rigid separation of action from production, and his justification of the subservience of slaves and others to the virtue – or arete – of a few justified the ideal of aristocracy.

Reference to them is made according to the organization of Immanuel Bekker's Royal Prussian Academy edition ( Aristotelis Opera edidit Academia Regia Borussica, Berlin, 1831 – 1870 ), which in turn is based on ancient classifications of these works.

In 2009, the American Anthropological Association's Commission on the Engagement of Anthropology with the US Security and Intelligence Communities released its final report concluding, in part, that, " When ethnographic investigation is determined by military missions, not subject to external review, where data collection occurs in the context of war, integrated into the goals of counterinsurgency, and in a potentially coercive environment – all characteristic factors of the HTS concept and its application – it can no longer be considered a legitimate professional exercise of anthropology.

Apollo ( Attic, Ionic, and Homeric Greek:, Apollōn ( gen .: ); Doric:, Apellōn ; Arcadocypriot:, Apeilōn ; Aeolic:, Aploun ; ) is one of the most important and complex of the Olympian deities in ancient Greek and Roman religion, Greek and Roman mythology, and Greco – Roman Neopaganism.

The last stage in the development of the Kouros type is the late archaic period ( 520 – 485 BC ), in which the Greek sculpture attained a full knowledge of human anatomy and used to create a relative harmonious whole.

These form thirteen established families ( plus perhaps Shompen, which is poorly attested, as a fourteenth ), which have traditionally been grouped into two, as Mon – Khmer and Munda.

However, Ancient Egyptian is highly divergent from Proto-Afroasiatic ( Trombetti 1905: 1 – 2 ), and considerable time must have elapsed in between them.

* Independence of observations – this is an assumption of the model that simplifies the statistical analysis.

The ANOVA F – test ( of the null-hypothesis that all treatments have exactly the same effect ) is recommended as a practical test, because of its robustness against many alternative distributions.

Under Parthian and Sassanian Iranian empires, scholars concentrated on exchanging knowledge and inventions by the countries around them – India, China, and the Roman Empire, when it is thought to be expanded over the other countries.

In the famous long scroll Along the River During the Qingming Festival painted by Zhang Zeduan ( 1085 – 1145 AD ) during the Song Dynasty ( 960 – 1297 AD ), a suanpan is clearly seen lying beside an account book and doctor's prescriptions on the counter of an apothecary's ( Feibao ).

Alphabets often come to be associated with a standard ordering of their letters, which can then be used for purposes of collation – namely for the listing of words and other items in what is called alphabetical order.

A distinction is sometimes made between the smaller adobes, which are about the size of ordinary baked bricks, and the larger adobines, some of which may be one to two yards ( 1 – 2 m ) long.

On average, the Atlantic is the saltiest major ocean ; surface water salinity in the open ocean ranges from 33 to 37 parts per thousand ( 3. 3 – 3. 7 %) by mass and varies with latitude and season.

It is named after André-Marie Ampère ( 1775 – 1836 ), French mathematician and physicist, considered the father of electrodynamics.

As the ship moves, momentum is not conserved – the ship eventually comes to a stop again when not thrusting.

The Asterales order probably originated in the Cretaceous ( 145 – 65 Mya ) on the supercontinent Gondwana which broke up from 184 – 80 Mya, forming the area that is now Australia, South America, Africa, India and Antarctica.

An Oligocene ( 34 – 23 Mya ) pollen is known for Asteraceae and Goodeniaceae, and seeds from Oligocene and Miocene ( 23 – 5. 3 Mya ) are known for Menyanthaceae and Campanulaceae respectively.